4CT2

Human PDK1-PKCzeta Kinase Chimera

Summary for 4CT2

Entry DOI	10.2210/pdb4ct2/pdb
Related	4CT1
Descriptor	3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1, ADENOSINE-5'-TRIPHOSPHATE, DITHIANE DIOL, ... (5 entities in total)
Functional Keywords	transferase, allosteric regulation, allosteric site, phosphorylation, agc protein kinase, chimeric protein
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: O15530
Total number of polymer chains	1
Total formula weight	36052.96
Authors	Schulze, J.O.,Zhang, H.,Lopez-Garcia, L.A.,Biondi, R.M. (deposition date: 2014-03-11, release date: 2014-05-28, Last modification date: 2023-12-20)
Primary citation	Zhang, H.,Neimanis, S.,Lopez-Garcia, L.A.,Arencibia, J.M.,Amon, S.,Stroba, A.,Zeuzem, S.,Proschak, E.,Stark, H.,Bauer, A.F.,Busschots, K.,Jorgensen, T.J.,Engel, M.,Schulze, J.O.,Biondi, R.M. Molecular Mechanism of Regulation of the Atypical Protein Kinase C by N-Terminal Domains and an Allosteric Small Compound. Chem.Biol., 21:754-, 2014 Cited by PubMed: 24836908 DOI: 10.1016/J.CHEMBIOL.2014.04.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation