4CT2
Human PDK1-PKCzeta Kinase Chimera
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 | polymer | 311 | 35370.6 | 1 | UniProt (O15530) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | HPDK1 |
2 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
3 | A | DITHIANE DIOL | non-polymer | 152.2 | 1 | Chemie (DTD) | |||
4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
5 | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A: 50 - 359 (UniProt: O15530)
PDB | External Database | Details |
---|---|---|
Gly 49 | - | expression tag |
Val 113 | Leu 113 | engineered mutation |
Val 118 | Ile 118 | engineered mutation |
His 119 | Ile 119 | engineered mutation |
Ile 124 | Val 124 | engineered mutation |
Gln 128 | Thr 128 | engineered mutation |
Lys 131 | Arg 131 | engineered mutation |
Cys 148 | Thr 148 | engineered mutation |
Leu 157 | Phe 157 | engineered mutation |
Gly 288 | Tyr 288 | engineered mutation |
Ala 292 | Gln 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35370.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 682.4 | |
All* | Total formula weight | 36053.0 |