4Z9D
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![BU of 4z9d by Molmil](/molmil-images/mine/4z9d) | EcPltA | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pertussis toxin-like subunit ArtA, SODIUM ION | 著者 | Littler, D.R, Johnson, M.D, Summers, R.J, Schembri, M.A, Rossjohn, J, Beddoe, T. | 登録日 | 2015-04-10 | 公開日 | 2016-10-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G proteins. J. Biol. Chem., 2017
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1K4R
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![BU of 1k4r by Molmil](/molmil-images/mine/1k4r) | Structure of Dengue Virus | 分子名称: | MAJOR ENVELOPE PROTEIN E | 著者 | Kuhn, R.J, Zhang, W, Rossmann, M.G, Pletnev, S.V, Corver, J, Lenches, E, Jones, C.T, Mukhopadhyay, S, Chipman, P.R, Strauss, E.G, Baker, T.S, Strauss, J.H. | 登録日 | 2001-10-08 | 公開日 | 2002-03-13 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (24 Å) | 主引用文献 | Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell(Cambridge,Mass.), 108, 2002
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1EWL
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4HBP
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![BU of 4hbp by Molmil](/molmil-images/mine/4hbp) | Crystal Structure of FAAH in complex with inhibitor | 分子名称: | 4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyridin-3-yl)piperazine-1-carboxamide, Fatty-acid amide hydrolase 1 | 著者 | Behnke, C, Skene, R.J. | 登録日 | 2012-09-28 | 公開日 | 2013-02-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Synthesis, SAR study, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase (FAAH) inhibitors. Bioorg.Med.Chem., 21, 2013
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7S6E
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![BU of 7s6e by Molmil](/molmil-images/mine/7s6e) | Crystal structure of UrtA from Synechococcus CC9311 in complex with urea and calcium | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Shah, B.S, Mikolajek, H, Mykhaylyk, V, Orr, C.M, Owens, R.J, Paulsen, I.T. | 登録日 | 2021-09-14 | 公開日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.973 Å) | 主引用文献 | Crystal structure of UrtA from Synechococcus CC9311 in complex with urea and calcium To Be Published
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7S6F
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![BU of 7s6f by Molmil](/molmil-images/mine/7s6f) | Crystal structure of UrtA1 from Synechococcus WH8102 in complex with urea and calcium | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Putative urea ABC transporter, ... | 著者 | Shah, B.S, Mikolajek, H, Orr, C.M, Mykhaylyk, V, Owens, R.J, Paulsen, I.T. | 登録日 | 2021-09-14 | 公開日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of UrtA1 from Synechococcus WH8102 in complex with urea and calcium To Be Published
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5FOG
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![BU of 5fog by Molmil](/molmil-images/mine/5fog) | Crystal structure of hte Cryptosporidium muris cytosolic leucyl-tRNA synthetase editing domain complex with a post-transfer editing analogue of norvaline (Nv2AA) | 分子名称: | 1,2-ETHANEDIOL, 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, LEUCYL-TRNA SYNTHETASE, ... | 著者 | Palencia, A, Liu, R.J, Lukarska, M, Gut, J, Bougdour, A, Touquet, B, Wang, E.D, Alley, M.R.K, Rosenthal, P.J, Hakimi, M.A, Cusack, S. | 登録日 | 2015-11-20 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cryptosporidium and Toxoplasma Parasites are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase. Antimicrob.Agents Chemother., 60, 2016
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6GXD
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![BU of 6gxd by Molmil](/molmil-images/mine/6gxd) | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography: FAcD752MS after reaction initiation | 分子名称: | CHLORIDE ION, fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Mueller-Werkmeister, H, Tellkamp, F, Stuart, W, Persch, E, De Gasparo, R, Diederich, F, Pai, E.F, Miller, R.J.D. | 登録日 | 2018-06-27 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography. Nat. Methods, 15, 2018
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4J53
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![BU of 4j53 by Molmil](/molmil-images/mine/4j53) | Crystal structure of PLK1 in complex with TAK-960 | 分子名称: | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide, ACETATE ION, Serine/threonine-protein kinase PLK1, ... | 著者 | Hosfield, D.J, Skene, R.J. | 登録日 | 2013-02-07 | 公開日 | 2013-05-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1). Bioorg.Med.Chem.Lett., 23, 2013
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4HDI
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![BU of 4hdi by Molmil](/molmil-images/mine/4hdi) | Crystal Structure of 3E5 IgG3 FAB from mus musculus | 分子名称: | Ig heavy chain V region RF, Ig gamma-3 chain C region, Kappa light chain variable region, ... | 著者 | Janda, A, Eryilmaz, E, Kim, J, Cordero, R.J.B, Cowburn, D, Casadevall, A. | 登録日 | 2012-10-02 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.449 Å) | 主引用文献 | Global structures of IgG isotypes expressing identical variable regions. Mol.Immunol., 56, 2013
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1FAI
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![BU of 1fai by Molmil](/molmil-images/mine/1fai) | THREE-DIMENSIONAL STRUCTURE OF TWO CRYSTAL FORMS OF FAB R19.9, FROM A MONOCLONAL ANTI-ARSONATE ANTIBODY | 分子名称: | IGG2B-KAPPA R19.9 FAB (HEAVY CHAIN), IGG2B-KAPPA R19.9 FAB (LIGHT CHAIN) | 著者 | Lascombe, M.B, Alzari, P.M, Poljak, R.J, Nisonoff, A. | 登録日 | 1992-05-27 | 公開日 | 1992-10-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Three-dimensional structure of two crystal forms of FabR19.9 from a monoclonal anti-arsonate antibody. Proc.Natl.Acad.Sci.USA, 89, 1992
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4ISF
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![BU of 4isf by Molmil](/molmil-images/mine/4isf) | Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-(6-fluoro-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-N-(1,3-thiazol-2-yl)propanamide | 分子名称: | (2S)-3-cyclohexyl-2-(6-fluoro-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-N-(1,3-thiazol-2-yl)propanamide, Glucokinase, IODIDE ION, ... | 著者 | Hosfield, D, Skene, R.J. | 登録日 | 2013-01-16 | 公開日 | 2013-03-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Design, synthesis and SAR of novel glucokinase activators. Bioorg.Med.Chem.Lett., 23, 2013
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1FC3
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4E8F
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![BU of 4e8f by Molmil](/molmil-images/mine/4e8f) | Structural Basis for the Activity of a Cytoplasmic RNA Terminal U-transferase | 分子名称: | ACETATE ION, GLYCEROL, Poly(A) RNA polymerase protein cid1 | 著者 | Yates, L.A, Fleurdepine, S, Rissland, O.S, DeColibus, L, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | 登録日 | 2012-03-20 | 公開日 | 2012-07-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase. Nat.Struct.Mol.Biol., 19, 2012
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4ISG
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![BU of 4isg by Molmil](/molmil-images/mine/4isg) | Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-[4-(methylsulfonyl)-2-oxopiperazin-1-yl]-N-(1,3-thiazol-2-yl)propanamide | 分子名称: | (2S)-3-cyclohexyl-2-[4-(methylsulfonyl)-2-oxopiperazin-1-yl]-N-(1,3-thiazol-2-yl)propanamide, Glucokinase, IODIDE ION, ... | 著者 | Hosfield, D, Skene, R.J. | 登録日 | 2013-01-16 | 公開日 | 2013-03-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.645 Å) | 主引用文献 | Design, synthesis and SAR of novel glucokinase activators. Bioorg.Med.Chem.Lett., 23, 2013
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1HR0
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![BU of 1hr0 by Molmil](/molmil-images/mine/1hr0) | CRYSTAL STRUCTURE OF INITIATION FACTOR IF1 BOUND TO THE 30S RIBOSOMAL SUBUNIT | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Morgan-Warren, R.J, Wimberly, B.T, Ramakrishnan, V. | 登録日 | 2000-12-20 | 公開日 | 2001-01-24 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of an initiation factor bound to the 30S ribosomal subunit. Science, 291, 2001
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4LT5
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![BU of 4lt5 by Molmil](/molmil-images/mine/4lt5) | Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA | 分子名称: | 1,2-ETHANEDIOL, DNA, MANGANESE (II) ION, ... | 著者 | Hashimoto, H, Pais, J.E, Zhang, X, Saleh, L, Fu, Z.Q, Dai, N, Correa, I.R, Roberts, R.J, Zheng, Y, Cheng, X. | 登録日 | 2013-07-23 | 公開日 | 2013-12-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.893 Å) | 主引用文献 | Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA. Nature, 506, 2014
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4E7X
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![BU of 4e7x by Molmil](/molmil-images/mine/4e7x) | Structural Basis for the Activity of a Cytoplasmic RNA Terminal U-transferase | 分子名称: | ACETATE ION, Poly(A) RNA polymerase protein cid1 | 著者 | Yates, L.A, Fleurdepine, S, Rissland, O.S, DeColibus, L, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | 登録日 | 2012-03-19 | 公開日 | 2012-07-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase. Nat.Struct.Mol.Biol., 19, 2012
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1GM2
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3O3T
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![BU of 3o3t by Molmil](/molmil-images/mine/3o3t) | Crystal Structure Analysis of M32A mutant of human CLIC1 | 分子名称: | Chloride intracellular channel protein 1 | 著者 | Fanucchi, S, Achilonu, I.A, Adamson, R.J, Fernandes, M.A, Stoychev, S, Dirr, H.W. | 登録日 | 2010-07-26 | 公開日 | 2010-08-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure Analysis of M32A mutant of human CLIC1 To be Published
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5U7R
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![BU of 5u7r by Molmil](/molmil-images/mine/5u7r) | Identification of A New Class of Potent Cdc7 Inhibitors Designed by Putative Pharmacophore Model: Synthesis and Biological Evaluation of 2,3-Dihydrothieno[3,2-d]pyrimidin-4(1H)-ones | 分子名称: | (1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1H-pyrazol-4-yl)-1'H-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'H)-one, Rho-associated protein kinase 2 | 著者 | Hoffman, I.D, Skene, R.J. | 登録日 | 2016-12-12 | 公開日 | 2017-03-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones. Bioorg. Med. Chem., 25, 2017
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5V18
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![BU of 5v18 by Molmil](/molmil-images/mine/5v18) | Structure of PHD2 in complex with 1,2,4-Triazolo-[1,5-a]pyridine | 分子名称: | 4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile, Egl nine homolog 1, FE (II) ION, ... | 著者 | Skene, R.J. | 登録日 | 2017-03-01 | 公開日 | 2017-06-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | 1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction. J. Med. Chem., 60, 2017
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5V1B
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![BU of 5v1b by Molmil](/molmil-images/mine/5v1b) | Structure of PHD1 in complex with 1,2,4-Triazolo-[1,5-a]pyridine | 分子名称: | 4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile, Egl nine homolog 2, FE (III) ION, ... | 著者 | Skene, R.J. | 登録日 | 2017-03-01 | 公開日 | 2017-06-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | 1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction. J. Med. Chem., 60, 2017
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1B34
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![BU of 1b34 by Molmil](/molmil-images/mine/1b34) | CRYSTAL STRUCTURE OF THE D1D2 SUB-COMPLEX FROM THE HUMAN SNRNP CORE DOMAIN | 分子名称: | PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1), PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2) | 著者 | Walke, S, Young, R.J, Kambach, C, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K. | 登録日 | 1998-12-17 | 公開日 | 2000-01-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell(Cambridge,Mass.), 96, 1999
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5VAD
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![BU of 5vad by Molmil](/molmil-images/mine/5vad) | Crystal structure of human Prolyl-tRNA synthetase (PRS) in complex with inhibitor | 分子名称: | 3-[(cyclohexanecarbonyl)amino]-N-(2,3-dihydro-1H-inden-2-yl)pyrazine-2-carboxamide, Bifunctional glutamate/proline--tRNA ligase, PROLINE, ... | 著者 | Okada, K, Skene, R.J. | 登録日 | 2017-03-24 | 公開日 | 2017-05-31 | 最終更新日 | 2017-06-07 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Discovery of a novel prolyl-tRNA synthetase inhibitor and elucidation of its binding mode to the ATP site in complex with l-proline. Biochem. Biophys. Res. Commun., 488, 2017
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