1EWL

CRYSTAL STRUCTURE OF CRUZAIN BOUND TO WRR-99

Summary for 1EWL

• Entry DOI: 10.2210/pdb1ewl/pdb
• Related: 1aim 1ewm 1ewo 1ewp 2aim
• Descriptor: CRUZAIN, N-[3-CARBOXY-2-HYDROXY-PROPIONYL]-D-HOMOPHENYLALANYL-AMINO-2-METHYLBUTANE (3 entities in total)
• Functional Keywords: papain-like cysteine protease, drug design, covalent inhibitor, cruzipain, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Trypanosoma cruzi
• Total number of polymer chains: 1
• Total formula weight: 23079.57

Authors

Brinen, L.S.,Gillmor, S.A.,Fletterick, R.J. (deposition date: 2000-04-26, release date: 2003-06-10, Last modification date: 2024-11-20)

• Primary citation: Brinen, L.S.,Gillmor, S.A.,Fletterick, R.J.; Crystal Structure of Cruzain bound to WRR-99; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)