1EWO

THE CYSTEINE PROTEASE CRUZAIN BOUND TO WRR-204

Summary for 1EWO

• Entry DOI: 10.2210/pdb1ewo/pdb
• Related: 1aim 1ewl 1ewm 1ewp 2aim
• Descriptor: CRUZAIN, N-[N'-BENZYLOXYCARBONYL-PHENYLALANINYL]-3-AMINO-5-PHENYL-PENTANE-1-SULFONIC ACID PHENYL ESTER (3 entities in total)
• Functional Keywords: cysteine protease, drug design, covalent inhibitor, cruzipain, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Trypanosoma cruzi
• Total number of polymer chains: 1
• Total formula weight: 23315.86

Authors

Brinen, L.S.,Gillmor, S.A.,Fletterick, R.J. (deposition date: 2000-04-26, release date: 2003-06-10, Last modification date: 2011-07-13)

• Primary citation: Brinen, L.S.,Gillmor, S.A.,Fletterick, R.J.; Crystal Structure of Cruzain bound to WRR-204; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)