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PDB: 2308 件

1T7T
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Crystal structure of the androgen receptor ligand binding domain in complex with 5-alpha dihydrotestosterone
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor
著者Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
登録日2004-05-10
公開日2004-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T8E
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T7 DNA Polymerase Ternary Complex with dCTP at the Insertion Site.
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 25-MER, ...
著者Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T.
登録日2004-05-12
公開日2004-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.
Embo J., 23, 2004
1T9J
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I-CreI(Q47E)/DNA complex
分子名称: 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', DNA endonuclease I-CreI
著者Chevalier, B, Sussman, D, Otis, C, Boudreau, D, Turmel, M, Lemieux, C, Stephens, K, Monnat Jr, R.J, Stoddard, B.L.
登録日2004-05-17
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Metal-Dependent DNA Cleavage Mechanism of the I-CreI LAGLIDADG Homing Endonuclease.
Biochemistry, 43, 2004
1TKD
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T7 DNA polymerase ternary complex with 8 oxo guanosine and dCMP at the elongation site
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*CP*CP*CP*AP*(8OG)P*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3'), ...
著者Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T.
登録日2004-06-08
公開日2004-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.
Embo J., 23, 2004
1UOU
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Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor
分子名称: 5-CHLORO-6-(1-(2-IMINOPYRROLIDINYL) METHYL) URACIL, THYMIDINE PHOSPHORYLASE
著者Norman, R.A, Barry, S.T, Bate, M, Breed, J, Colls, J.G, Ernill, R.J, Luke, R.W.A, Minshull, C.A, McAlister, M.S.B, McCall, E.J, McMiken, H.H.J, Paterson, D.S, Timms, D, Tucker, J.A, Pauptit, R.A.
登録日2003-09-23
公開日2004-01-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal Structure of Human Thymidine Phosphorylase in Complex with a Small Molecule Inhibitor
Structure, 12, 2004
1UWA
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L290F mutant rubisco from chlamydomonas
分子名称: 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ...
著者Karkehabadi, S, Taylor, T.C, Spreitzer, R.J, Andersson, I.
登録日2004-02-03
公開日2005-01-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Altered Intersubunit Interactions in Crystal Structures of Catalytically Compromised Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase
Biochemistry, 44, 2005
1T5Z
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Crystal Structure of the Androgen Receptor Ligand Binding Domain (LBD) with DHT and a peptide derived from its physiological coactivator ARA70
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 4
著者Estebanez-Perpina, E, Moore, J.M.R, Mar, E, Nguyen, P, Delgado-Rodrigues, E, Baxter, J.D, Webb, P, Fletterick, R.J, Guy, R.K.
登録日2004-05-05
公開日2005-01-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor.
J.Biol.Chem., 280, 2005
1T63
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Crystal Structure of the Androgen Receptor Ligand Binding Domain with DHT and a peptide derived from its physiological coactivator GRIP1 NR box3
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 2
著者Estebanez-Perpina, E, Moore, J.M.R, Mar, E, Nguyen, P, Delgado-Rodrigues, E, Baxter, J.D, Webb, P, Fletterick, R.J, Guy, R.K.
登録日2004-05-05
公開日2005-01-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor.
J.Biol.Chem., 280, 2005
1T76
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Crystal structure of the androgen receptor ligand binding domain in complex with a WxxVW motif
分子名称: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ...
著者Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
登録日2004-05-08
公開日2004-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T7R
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Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLF motif
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, FxxLF motif peptide
著者Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
登録日2004-05-10
公開日2004-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T73
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Crystal structure of the androgen receptor ligand binding domain in complex with a FxxFF motif
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, FxxFF motif peptide, ...
著者Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
登録日2004-05-07
公開日2004-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1TRM
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THE THREE-DIMENSIONAL STRUCTURE OF ASN102 MUTANT OF TRYPSIN. ROLE OF ASP102 IN SERINE PROTEASE CATALYSIS
分子名称: BENZAMIDINE, CALCIUM ION, TRYPSIN
著者Sprang, S, Standing, T, Fletterick, R.J.
登録日1987-10-21
公開日1988-07-16
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis.
Science, 237, 1987
1TZN
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Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore bound to the VWA domain of CMG2, an anthrax toxin receptor
分子名称: Anthrax toxin receptor 2, CALCIUM ION, MAGNESIUM ION, ...
著者Lacy, D.B, Wigelsworth, D.J, Melnyk, R.A, Collier, R.J.
登録日2004-07-10
公開日2004-08-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation
Proc.Natl.Acad.Sci.USA, 101, 2004
1TZO
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Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
分子名称: CALCIUM ION, Protective antigen
著者Lacy, D.B, Wigelsworth, D.J, Melnyk, R.A, Collier, R.J.
登録日2004-07-10
公開日2004-08-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation
Proc.Natl.Acad.Sci.USA, 101, 2004
1T65
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Crystal structure of the androgen receptor ligand binding domain with DHT and a peptide derived form its physiological coactivator GRIP1 NR box 2 bound in a non-helical conformation
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 2
著者Estebanez-Perpina, E, Moore, J.M.R, Mar, E, Nguyen, P, Delgado-Rodrigues, E, Baxter, J.D, Webb, P, Fletterick, R.J, Guy, R.K.
登録日2004-05-05
公開日2005-01-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor.
J.Biol.Chem., 280, 2005
1TGE
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The structure of immature Dengue virus at 12.5 angstrom
分子名称: envelope glycoprotein
著者Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G.
登録日2004-05-28
公開日2004-09-28
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (12.5 Å)
主引用文献Conformational changes of the flavivirus e glycoprotein.
Structure, 12, 2004
1T43
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Crystal Structure Analysis of E.coli Protein (N5)-Glutamine Methyltransferase (HemK)
分子名称: Protein methyltransferase hemK, S-ADENOSYL-L-HOMOCYSTEINE
著者Yang, Z, Shipman, L, Zhang, M, Anton, B.P, Roberts, R.J, Cheng, X.
登録日2004-04-28
公開日2004-06-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural characterization and comparative phylogenetic analysis of Escherichia coli HemK, a protein (N5)-glutamine methyltransferase.
J.Mol.Biol., 340, 2004
1VKJ
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Crystal structure of heparan sulfate 3-O-sulfotransferase isoform 1 in the presence of PAP
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, SULFATE ION, heparan sulfate (glucosamine) 3-O-sulfotransferase 1
著者Thorp, S, Lee, K.A, Negishi, M, Linhardt, R.J, Liu, J, Pedersen, L.C.
登録日2004-05-25
公開日2004-06-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1
J.Biol.Chem., 279, 2004
1VYX
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Solution structure of the KSHV K3 N-terminal domain
分子名称: ORF K3, ZINC ION
著者Dodd, R.B, Allen, M.D, Brown, S.E, Sanderson, C.M, Duncan, L.M, lehner, P.J, Bycroft, M, Read, R.J.
登録日2004-05-07
公開日2004-10-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of the Kaposi'S Sarcoma-Associated Herpesvirus K3 N-Terminal Domain Reveals a Novel E2-Binding C4Hc3-Type Ring Domain
J.Biol.Chem., 279, 2004
1W53
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Kinase recruitment domain of the stress phosphatase RsbU
分子名称: GLYCEROL, PHOSPHOSERINE PHOSPHATASE RSBU, XENON
著者Delumeau, O, Dutta, S, Brigulla, M, Kuhnke, G, Hardwick, S.W, Voelker, U, Yudkin, M.D, Lewis, R.J.
登録日2004-08-05
公開日2004-08-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Functional and Structural Characterization of Rsbu, a Stress Signaling Protein Phosphatase 2C
J.Biol.Chem., 279, 2004
1VKG
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Crystal Structure of Human HDAC8 complexed with CRA-19156
分子名称: 5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE, Histone deacetylase 8, SODIUM ION, ...
著者Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W.
登録日2004-05-13
公開日2004-07-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases
Structure, 12, 2004
5F1U
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biomimetic design results in a potent allosteric inhibitor of dihydrodipicolinate synthase from Campylobacter jejuni
分子名称: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ...
著者Conly, C.J.T, Palmer, D.R.J, Sanders, D.A.R.
登録日2015-11-30
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni.
J.Am.Chem.Soc., 138, 2016
5F20
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Structure of TYK2 with inhibitor 4: 3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one
分子名称: 3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one, Non-receptor tyrosine-protein kinase TYK2
著者Skene, R.J.
登録日2015-12-01
公開日2016-01-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors.
J.Med.Chem., 59, 2016
7P4A
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Non-canonical Staphylococcus aureus pathogenicity island repression.
分子名称: Sri, Stl
著者Miguel-Romero, L, Alqasmi, M, Bacarizo, J, Tan, J.A, Cogdell, R.J, Chen, J, Byron, O, Christie, G.E, Marina, A, Penades, J.R.
登録日2021-07-10
公開日2022-07-27
最終更新日2022-11-16
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Non-canonical Staphylococcus aureus pathogenicity island repression.
Nucleic Acids Res., 50, 2022
5EYV
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Crystal Structure of Adenylosuccinate lyase from Schistosoma mansoni in APO form.
分子名称: Adenylosuccinate lyase
著者Romanello, L, Torini, J.R, Bird, L.E, Nettleship, J.E, Owens, R.J, Reddivari, Y, Brandao-Neto, J, Pereira, H.M.
登録日2015-11-25
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
Mol. Biochem. Parasitol., 214, 2017

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