5F1U
biomimetic design results in a potent allosteric inhibitor of dihydrodipicolinate synthase from Campylobacter jejuni
Summary for 5F1U
Entry DOI | 10.2210/pdb5f1u/pdb |
Related | 5F1V |
Descriptor | 4-hydroxy-tetrahydrodipicolinate synthase, (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, TETRAETHYLENE GLYCOL, ... (7 entities in total) |
Functional Keywords | schiff-base, aldolase, tim barrel, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Campylobacter jejuni |
Cellular location | Cytoplasm : Q9PPB4 |
Total number of polymer chains | 4 |
Total formula weight | 131891.37 |
Authors | Conly, C.J.T.,Palmer, D.R.J.,Sanders, D.A.R. (deposition date: 2015-11-30, release date: 2016-02-17, Last modification date: 2023-09-27) |
Primary citation | Skovpen, Y.V.,Conly, C.J.,Sanders, D.A.,Palmer, D.R. Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni. J.Am.Chem.Soc., 138:2014-2020, 2016 Cited by PubMed: 26836694DOI: 10.1021/jacs.5b12695 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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