3QQZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qqz by Molmil](/molmil-images/mine/3qqz) | Crystal structure of the C-terminal domain of the yjiK protein from Escherichia coli CFT073 | 分子名称: | CALCIUM ION, Putative uncharacterized protein yjiK | 著者 | Stein, A, Chhor, G, Nocek, B, Fenske, R.J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-02-16 | 公開日 | 2011-03-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of the C-terminal domain of the yjiK protein from Escherichia coli CFT073 TO BE PUBLISHED
|
|
4MDO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mdo by Molmil](/molmil-images/mine/4mdo) | Crystal structure of a GH1 beta-glucosidase from the fungus Humicola insolens | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Giuseppe, P.O, Souza, T.A.C.B, Souza, F.H.M, Zanphorlin, L.M, Machado, C.B, Ward, R.J, Jorge, J.A, Furriel, R.P.M, Murakami, M.T. | 登録日 | 2013-08-23 | 公開日 | 2014-06-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for glucose tolerance in GH1 beta-glucosidases. Acta Crystallogr.,Sect.D, 70, 2014
|
|
8CKP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ckp by Molmil](/molmil-images/mine/8ckp) | X-ray structure of the crystallization-prone form of subfamily III haloalkane dehalogenase DhmeA from Haloferax mediterranei | 分子名称: | Alpha/beta fold hydrolase, CHLORIDE ION | 著者 | Marek, M, Chmelova, K, Schenkmayerova, A, Croll, T, Read, R.J, Diederichs, K. | 登録日 | 2023-02-16 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography. Protein Sci., 32, 2023
|
|
5BTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5btg by Molmil](/molmil-images/mine/5btg) | Crystal structure of a topoisomerase II complex | 分子名称: | (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, DNA gyrase subunit A, DNA gyrase subunit B, ... | 著者 | Blower, T.R, Williamson, B.H, Kerns, R.J, Berger, J.M. | 登録日 | 2015-06-03 | 公開日 | 2016-03-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
3RKG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rkg by Molmil](/molmil-images/mine/3rkg) | Structural and Functional Characterization of the Yeast Mg2+ Channel Mrs2 | 分子名称: | 1,2-ETHANEDIOL, Magnesium transporter MRS2, mitochondrial | 著者 | Khan, M.B, Sponder, G, Sjoeblom, B, Svidova, S, Schweyen, R.J, Carugo, O, Djinovic-Carugo, K. | 登録日 | 2011-04-18 | 公開日 | 2012-04-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Structural and functional characterization of the N-terminal domain of the yeast Mg(2+) channel Mrs2. Acta Crystallogr.,Sect.D, 69, 2013
|
|
3O3F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o3f by Molmil](/molmil-images/mine/3o3f) | T. maritima RNase H2 D107N in complex with nucleic acid substrate and magnesium ions | 分子名称: | DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), MAGNESIUM ION, ... | 著者 | Rychlik, M.P, Chon, H, Cerritelli, S.M, Klimek, P, Crouch, R.J, Nowotny, M. | 登録日 | 2010-07-24 | 公開日 | 2010-12-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage. Mol.Cell, 40, 2010
|
|
3PZ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pz0 by Molmil](/molmil-images/mine/3pz0) | The crystal structure of AaLeuRS-CP1 | 分子名称: | CALCIUM ION, Leucyl-tRNA synthetase subunit alpha | 著者 | Liu, R.J, Wang, E.D. | 登録日 | 2010-12-13 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase Biochem.J., 440, 2011
|
|
3PZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pzt by Molmil](/molmil-images/mine/3pzt) | Structure of the endo-1,4-beta-glucanase from Bacillus subtilis 168 with manganese(II) ion | 分子名称: | Endoglucanase, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Santos, C.R, Paiva, J.H, Akao, P.K, Meza, A.N, Silva, J.C, Squina, F.M, Ward, R.J, Ruller, R, Murakami, M.T. | 登録日 | 2010-12-14 | 公開日 | 2011-09-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Dissecting structure-function-stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168. Biochem.J., 441, 2012
|
|
3NWF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nwf by Molmil](/molmil-images/mine/3nwf) | Glycoprotein B from Herpes simplex virus type 1, low-pH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B, MESO-ERYTHRITOL, ... | 著者 | Stampfer, S.D, Lou, H, Cohen, G.H, Eisenberg, R.J, Heldwein, E.E. | 登録日 | 2010-07-09 | 公開日 | 2010-12-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. J.Virol., 84, 2010
|
|
3O3L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o3l by Molmil](/molmil-images/mine/3o3l) | Structure of the PTP-like phytase from Selenomonas ruminantium in complex with myo-inositol (1,3,4,5)tetrakisphosphate | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Gruninger, R.J, Selinger, L.B, Mosimann, S.C. | 登録日 | 2010-07-25 | 公開日 | 2011-12-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural analysis of substrate binding in PTPLPs To be Published
|
|
5BTC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5btc by Molmil](/molmil-images/mine/5btc) | Crystal structure of a topoisomerase II complex | 分子名称: | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, DNA gyrase subunit A, DNA gyrase subunit B, ... | 著者 | Blower, T.R, Williamson, B.H, Kerns, R.J, Berger, J.M. | 登録日 | 2015-06-02 | 公開日 | 2016-03-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
3PLV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3plv by Molmil](/molmil-images/mine/3plv) | Structure of Hub-1 protein in complex with Snu66 peptide (HINDII) | 分子名称: | 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1 | 著者 | Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S. | 登録日 | 2010-11-15 | 公開日 | 2011-06-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Nature, 474, 2011
|
|
2CO7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2co7 by Molmil](/molmil-images/mine/2co7) | Salmonella enterica SafA pilin in complex with the SafB chaperone (Type II) | 分子名称: | PUTATIVE FIMBRIAE ASSEMBLY CHAPERONE, SAFA PILUS SUBUNIT, SULFATE ION | 著者 | Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G. | 登録日 | 2006-05-25 | 公開日 | 2006-06-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism Mol.Cell, 22, 2006
|
|
3PZV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pzv by Molmil](/molmil-images/mine/3pzv) | C2 crystal form of the endo-1,4-beta-glucanase from Bacillus subtilis 168 | 分子名称: | Endoglucanase | 著者 | Santos, C.R, Paiva, J.H, Akao, P.K, Meza, A.N, Silva, J.C, Squina, F.M, Ward, R.J, Ruller, R, Murakami, M.T. | 登録日 | 2010-12-14 | 公開日 | 2011-09-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.867 Å) | 主引用文献 | Dissecting structure-function-stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168. Biochem.J., 441, 2012
|
|
4LFT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lft by Molmil](/molmil-images/mine/4lft) | Structure of alpha-elapitoxin-Dpp2d isolated from Black Mamba (Dendroaspis polylepis) venom | 分子名称: | Alpha-elapitoxin-Dpp2a | 著者 | Wang, C.I.A, Reeks, T, Lewis, R.J, Alewood, P.F, Durek, T. | 登録日 | 2013-06-27 | 公開日 | 2014-06-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Isolation and Structural and Pharmacological Characterization of alpha-Elapitoxin-Dpp2d, an Amidated Three Finger Toxin from Black Mamba Venom. Biochemistry, 53, 2014
|
|
5BTL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5btl by Molmil](/molmil-images/mine/5btl) | Crystal structure of a topoisomerase II complex | 分子名称: | 1-cyclopropyl-6-fluoro-8-methyl-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA gyrase subunit A, DNA gyrase subunit B, ... | 著者 | Blower, T.R, Williamson, B.H, Kerns, R.J, Berger, J.M. | 登録日 | 2015-06-03 | 公開日 | 2016-03-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
3O3H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o3h by Molmil](/molmil-images/mine/3o3h) | T. maritima RNase H2 D107N in complex with nucleic acid substrate and manganese ions | 分子名称: | DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), MANGANESE (II) ION, ... | 著者 | Rychlik, M.P, Chon, H, Cerritelli, S.M, Klimek, P, Crouch, R.J, Nowotny, M. | 登録日 | 2010-07-24 | 公開日 | 2010-12-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage. Mol.Cell, 40, 2010
|
|
3O5X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o5x by Molmil](/molmil-images/mine/3o5x) | Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor | 分子名称: | 3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3-triazol-4-yl}-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Zhang, Z.-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C, Wu, L, Gunawan, A.M, Wang, L, Chan, R.J. | 登録日 | 2010-07-28 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2). J.Med.Chem., 53, 2010
|
|
3ME4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3me4 by Molmil](/molmil-images/mine/3me4) | Crystal structure of mouse RANK | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Walter, S.W, Liu, C, Zhu, X, Wu, Y, Owens, R.J, Stuart, D.I, Gao, B, Ren, J. | 登録日 | 2010-03-31 | 公開日 | 2010-06-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structural and Functional Insights of RANKL-RANK Interaction and Signaling. J.Immunol., 2010
|
|
4MDP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mdp by Molmil](/molmil-images/mine/4mdp) | Crystal structure of a GH1 beta-glucosidase from the fungus Humicola insolens in complex with glucose | 分子名称: | Beta-glucosidase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Giuseppe, P.O, Souza, T.A.C.B, Souza, F.H.M, Zanphorlin, L.M, Machado, C.B, Ward, R.J, Jorge, J.A, Furriel, R.P.M, Murakami, M.T. | 登録日 | 2013-08-23 | 公開日 | 2014-06-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural basis for glucose tolerance in GH1 beta-glucosidases. Acta Crystallogr.,Sect.D, 70, 2014
|
|
5A28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a28 by Molmil](/molmil-images/mine/5a28) | Leishmania major N-myristoyltransferase in complex with a chlorophenyl 1,3,4-oxadiazole inhibitor. | 分子名称: | 4-(4-chloro-2-{5-[(trimethyl-1H-pyrazol-4-yl)methyl]-1,3,4-oxadiazol-2-yl}phenoxy)piperidine, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, ... | 著者 | Rackham, M.D, Yu, Z, Brannigan, J.A, Heal, W.P, Paape, D, Barker, K.V, Wilkinson, A.J, Smith, D.F, Tate, E.W, Leatherbarrow, R.J. | 登録日 | 2015-05-15 | 公開日 | 2016-03-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Discovery of High Affinity Inhibitors of Leishmania Donovani N-Myristoyltransferase. Medchemcomm, 6, 2015
|
|
3ME2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3me2 by Molmil](/molmil-images/mine/3me2) | Crystal structure of mouse RANKL-RANK complex | 分子名称: | CHLORIDE ION, SODIUM ION, Tumor necrosis factor ligand superfamily member 11, ... | 著者 | Walter, S.W, Liu, C.Z, Zhu, X.K, Wu, Y, Owens, R.J, Stuart, D.I, Gao, B, Ren, J. | 登録日 | 2010-03-31 | 公開日 | 2010-06-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and Functional Insights of RANKL-RANK Interaction and Signaling. J.Immunol., 2010
|
|
5A27
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a27 by Molmil](/molmil-images/mine/5a27) | Leishmania major N-myristoyltransferase in complex with a chlorophenyl 1,2,4-oxadiazole inhibitor. | 分子名称: | 5-chloranyl-N-[2-(3-methoxyphenyl)ethanimidoyl]-2-piperidin-4-yloxy-benzamide, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, ... | 著者 | Rackham, M.D, Yu, Z, Brannigan, J.A, Heal, W.P, Paape, D, Barker, K.V, Wilkinson, A.J, Smith, D.F, Tate, E.W, Leatherbarrow, R.J. | 登録日 | 2015-05-15 | 公開日 | 2016-03-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Discovery of High Affinity Inhibitors of Leishmania Donovani N-Myristoyltransferase. Medchemcomm, 6, 2015
|
|
3RV8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rv8 by Molmil](/molmil-images/mine/3rv8) | Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Cyclopropyl R-Group | 分子名称: | 3-{[(E)-1-carboxy-2-cyclopropylethenyl]oxy}-2-hydroxybenzoic acid, 3-{[(Z)-1-carboxy-2-cyclopropylethenyl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI | 著者 | Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2011-05-06 | 公開日 | 2012-05-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis Biochemistry, 51, 2012
|
|
2C1F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c1f by Molmil](/molmil-images/mine/2c1f) | |