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5A27

Leishmania major N-myristoyltransferase in complex with a chlorophenyl 1,2,4-oxadiazole inhibitor.

Summary for 5A27
Entry DOI10.2210/pdb5a27/pdb
Related5A28
DescriptorGLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA, 5-chloranyl-N-[2-(3-methoxyphenyl)ethanimidoyl]-2-piperidin-4-yloxy-benzamide, ... (5 entities in total)
Functional Keywordstransferase, myristoylation, drug design
Biological sourceLEISHMANIA MAJOR
Total number of polymer chains1
Total formula weight48914.21
Authors
Primary citationRackham, M.D.,Yu, Z.,Brannigan, J.A.,Heal, W.P.,Paape, D.,Barker, K.V.,Wilkinson, A.J.,Smith, D.F.,Leatherbarrow, R.J.,Tate, E.W.
Discovery of High Affinity Inhibitors of Leishmania Donovani N-Myristoyltransferase.
Medchemcomm, 6:1761-, 2015
Cited by
PubMed: 26962429
DOI: 10.1039/C5MD00241A
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.37 Å)
Structure validation

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