6KJL
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![BU of 6kjl by Molmil](/molmil-images/mine/6kjl) | Xylanase J from Bacillus sp. strain 41M-1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Manami, S, Teisuke, T, Nakatani, K, Katano, K, Kojima, K, Saka, N, Mikami, B, Yatsunami, R, Nakamura, S, Yasukawa, K. | Deposit date: | 2019-07-22 | Release date: | 2019-09-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Increase in the thermostability of GH11 xylanase XynJ from Bacillus sp. strain 41M-1 using site saturation mutagenesis. Enzyme.Microb.Technol., 130, 2019
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6KLD
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![BU of 6kld by Molmil](/molmil-images/mine/6kld) | Structure of apo Machupo virus polymerase | Descriptor: | MANGANESE (II) ION, RNA-directed RNA polymerase L, ZINC ION | Authors: | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | Deposit date: | 2019-07-30 | Release date: | 2020-03-18 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structural insight into arenavirus replication machinery. Nature, 579, 2020
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462D
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![BU of 462d by Molmil](/molmil-images/mine/462d) | CRYSTAL STRUCTURE OF THE HIV-1 GENOMIC RNA DIMERIZATION INITIATION SITE | Descriptor: | MAGNESIUM ION, RNA (5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G) -3') | Authors: | Ennifar, E, Yusupov, M, Walter, P, Marquet, R, Ehresmann, C, Ehresmann, B, Dumas, P. | Deposit date: | 1999-03-18 | Release date: | 1999-12-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges. Structure Fold.Des., 7, 1999
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6KLE
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![BU of 6kle by Molmil](/molmil-images/mine/6kle) | Monomeric structure of Machupo virus polymerase bound to vRNA promoter | Descriptor: | MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ... | Authors: | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | Deposit date: | 2019-07-30 | Release date: | 2020-03-18 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural insight into arenavirus replication machinery. Nature, 579, 2020
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4A91
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![BU of 4a91 by Molmil](/molmil-images/mine/4a91) | Crystal structure of the glutamyl-queuosine tRNAAsp synthetase from E. coli complexed with L-glutamate | Descriptor: | GLUTAMIC ACID, GLUTAMYL-Q TRNA(ASP) SYNTHETASE, ZINC ION | Authors: | Blaise, M, Olieric, V, Sauter, C, Lorber, B, Roy, B, Karmakar, S, Banerjee, R, Becker, H.D, Kern, D. | Deposit date: | 2011-11-22 | Release date: | 2012-01-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of Glutamyl-Queuosine Trnaasp Synthetase Complexed with L-Glutamate: Structural Elements Mediating tRNA-Independent Activation of Glutamate and Glutamylation of Trnaasp Anticodon. J.Mol.Biol., 381, 2008
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4AGN
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![BU of 4agn by Molmil](/molmil-images/mine/4agn) | Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5116 | Descriptor: | 2-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4-(3-HYDROXYPROP-1-YN-1-YL)-6-IODOPHENOL, CELLULAR TUMOR ANTIGEN P53, ZINC ION | Authors: | Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R. | Deposit date: | 2012-01-30 | Release date: | 2012-03-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
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6NUL
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![BU of 6nul by Molmil](/molmil-images/mine/6nul) | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: N137A REDUCED (150K) | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | Authors: | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | Deposit date: | 1997-01-09 | Release date: | 1997-03-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
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4A3V
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![BU of 4a3v by Molmil](/molmil-images/mine/4a3v) | yeast regulatory particle proteasome assembly chaperone Hsm3 in complex with Rpt1 C-terminal fragment | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 7 HOMOLOG, DNA MISMATCH REPAIR PROTEIN HSM3, LINKER | Authors: | Richet, N, Barrault, M.B, Godart, C, Murciano, B, Le Tallec, B, Rousseau, E, Ledu, M.H, Charbonnier, J.B, Legrand, P, Guerois, R, Peyroche, A, Ochsenbein, F. | Deposit date: | 2011-10-04 | Release date: | 2012-04-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Dual Functions of the Hsm3 Protein in Chaperoning and Scaffolding Regulatory Particle Subunits During the Proteasome Assembly. Proc.Natl.Acad.Sci.USA, 109, 2012
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4AKL
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![BU of 4akl by Molmil](/molmil-images/mine/4akl) | Structure of the Crimean-Congo Haemorrhagic Fever Virus Nucleocapsid Protein | Descriptor: | NUCLEOCAPSID, TRIETHYLENE GLYCOL | Authors: | Carter, S.D, Walter, C.T, Surtees, R, Bergeron, E, Ariza, A, Albarino, C.G, Nichol, S.T, Hiscox, J.A, Edwards, T.A, Barr, J.N. | Deposit date: | 2012-02-24 | Release date: | 2012-08-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure, Function, and Evolution of the Crimean-Congo Hemorrhagic Fever Virus Nucleocapsid Protein. J.Virol., 86, 2012
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4AN1
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![BU of 4an1 by Molmil](/molmil-images/mine/4an1) | PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN WITH A COVALENTLY BOUND INHIBITOR IC-4 | Descriptor: | (2S)-N-benzyl-2-({(2S)-2-[(1R)-1,2-dihydroxyethyl]pyrrolidin-1-yl}carbonyl)pyrrolidine-1-carboxamide, GLYCEROL, PROLYL ENDOPEPTIDASE | Authors: | Kaszuba, K, Rog, T, Danne, R, Canning, P, Fulop, V, Juhasz, T, Szeltner, Z, St-Pierre, J.F, Garcia-Horsman, A, Mannisto, P.T, Karttunen, M, Hokkanen, J, Bunker, A. | Deposit date: | 2012-03-14 | Release date: | 2012-05-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular Dynamics, Crystallography and Mutagenesis Studies on the Substrate Gating Mechanism of Prolyl Oligopeptidase. Biochimie, 94, 2012
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6IF3
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![BU of 6if3 by Molmil](/molmil-images/mine/6if3) | Complex structure of Rab35 and its effector ACAP2 | Descriptor: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Lin, L, Zhu, J, Zhang, R. | Deposit date: | 2018-09-18 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase. Structure, 27, 2019
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1UKG
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![BU of 1ukg by Molmil](/molmil-images/mine/1ukg) | Pterocarps angolensis lectin PAL in complex with methyl-alpha-mannose | Descriptor: | CALCIUM ION, MANGANESE (II) ION, lectin, ... | Authors: | Loris, R, Van Walle, I, De Greve, H, Beeckmans, S, Deboeck, F, Wyns, L, Bouckaert, J. | Deposit date: | 2003-08-21 | Release date: | 2004-02-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of Oligomannose Recognition by the Pterocarpus angolensis Seed Lectin J.Mol.Biol., 335, 2004
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4AGR
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![BU of 4agr by Molmil](/molmil-images/mine/4agr) | Structure of a tetrameric galectin from Cinachyrella sp. (Ball sponge) | Descriptor: | CHLORIDE ION, GALECTIN | Authors: | Freymann, D.M, Focia, P.J, Sakai, R, Swanson, G.T. | Deposit date: | 2012-01-31 | Release date: | 2012-08-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a Tetrameric Galectin from Cinachyrella Sp. (Ball Sponge). Acta Crystallogr.,Sect.D, 68, 2012
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4AK8
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![BU of 4ak8 by Molmil](/molmil-images/mine/4ak8) | Structure of F241L mutant of langerin carbohydrate recognition domain. | Descriptor: | C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K, CALCIUM ION, CHLORIDE ION, ... | Authors: | Chabrol, E, Thepaut, M, Dezutter-Dambuyant, C, Vives, C, Marcoux, J, Kahn, R, Valadeau-Guilemond, J, Vachette, P, Durand, D, Fieschi, F. | Deposit date: | 2012-02-22 | Release date: | 2013-04-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Alteration of the Langerin Oligomerization State Affects Birbeck Granule Formation. Biophys.J., 108, 2015
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4AGM
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![BU of 4agm by Molmil](/molmil-images/mine/4agm) | Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5086 | Descriptor: | 2-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4,6-DIIODOPHENOL, CELLULAR TUMOR ANTIGEN P53, ZINC ION | Authors: | Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R. | Deposit date: | 2012-01-30 | Release date: | 2012-03-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
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7E4L
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![BU of 7e4l by Molmil](/molmil-images/mine/7e4l) | |
4AQE
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![BU of 4aqe by Molmil](/molmil-images/mine/4aqe) | CRYSTAL STRUCTURE OF DEAFNESS ASSOCIATED MUTANT MOUSE CADHERIN-23 EC1- 2S70P AND PROTOCADHERIN-15 EC1-2 FORM I | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CADHERIN-23, CALCIUM ION, ... | Authors: | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | Deposit date: | 2012-04-16 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction Nature, 492, 2012
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4AI9
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![BU of 4ai9 by Molmil](/molmil-images/mine/4ai9) | JMJD2A Complexed with Daminozide | Descriptor: | CHLORIDE ION, DAMINOZIDE, GLYCEROL, ... | Authors: | Chowdhury, R, Schofield, C.J. | Deposit date: | 2012-02-08 | Release date: | 2012-10-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. J. Med. Chem., 55, 2012
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7ELC
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![BU of 7elc by Molmil](/molmil-images/mine/7elc) | Structure of monomeric complex of MACV L bound to Z and 3'-vRNA | Descriptor: | 3'-vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... | Authors: | Xu, X, Peng, R, Peng, Q, Shi, Y. | Deposit date: | 2021-04-09 | Release date: | 2021-05-05 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
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7ELA
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![BU of 7ela by Molmil](/molmil-images/mine/7ela) | Structure of Lassa virus polymerase in complex with 3'-vRNA and Z mutant (F36A) | Descriptor: | 3-'vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... | Authors: | Xu, X, Peng, R, Peng, Q, Shi, Y. | Deposit date: | 2021-04-09 | Release date: | 2021-05-05 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
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6ILL
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![BU of 6ill by Molmil](/molmil-images/mine/6ill) | Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 5.5 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Gao, G.F, Liu, S, Zhao, X, Peng, R. | Deposit date: | 2018-10-19 | Release date: | 2019-05-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B. Cell, 177, 2019
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6IN1
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![BU of 6in1 by Molmil](/molmil-images/mine/6in1) | Crystal structure of the first bromodomain of BRD4 in complex with 18-Crown-6 | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Bromodomain-containing protein 4, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide, ... | Authors: | Yokoyama, T, Kosaka, Y, Matsumoto, K, Kitakami, R, Nabeshima, Y, Mizuguchi, M. | Deposit date: | 2018-10-24 | Release date: | 2019-10-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crown Ethers as Transthyretin Amyloidogenesis Inhibitor To Be Published
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7EL9
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![BU of 7el9 by Molmil](/molmil-images/mine/7el9) | Structure of Machupo virus L polymerase in complex with Z protein and 3'-vRNA (dimeric complex) | Descriptor: | MANGANESE (II) ION, Machupo virus 3'-vRNA promoter, RING finger protein Z, ... | Authors: | Peng, R, Xu, X, Peng, Q, Shi, Y. | Deposit date: | 2021-04-09 | Release date: | 2021-05-05 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
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4AN0
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![BU of 4an0 by Molmil](/molmil-images/mine/4an0) | PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN WITH A COVALENTLY BOUND INHIBITOR IC-3 | Descriptor: | (2S)-1-[1-(4-phenylbutanoyl)-L-prolyl]pyrrolidine-2-carbonitrile, GLYCEROL, PROLYL ENDOPEPTIDASE | Authors: | Kaszuba, K, Rog, T, Danne, R, Canning, P, Fulop, V, Juhasz, T, Szeltner, Z, St-Pierre, J.F, Garcia-Horsman, A, Mannisto, P.T, Karttunen, M, Hokkanen, J, Bunker, A. | Deposit date: | 2012-03-14 | Release date: | 2012-05-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase. Biochimie, 94, 2012
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4AGV
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![BU of 4agv by Molmil](/molmil-images/mine/4agv) | Structure of a tetrameric galectin from Cinachyrella sp. (Ball sponge) | Descriptor: | GALECTIN | Authors: | Freymann, D.M, Focia, P.J, Sakai, R, Swanson, G.T. | Deposit date: | 2012-01-31 | Release date: | 2012-08-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of a Tetrameric Galectin from Cinachyrella Sp. (Ball Sponge). Acta Crystallogr.,Sect.D, 68, 2012
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