4AQE

CRYSTAL STRUCTURE OF DEAFNESS ASSOCIATED MUTANT MOUSE CADHERIN-23 EC1- 2S70P AND PROTOCADHERIN-15 EC1-2 FORM I

Summary for 4AQE

• Entry DOI: 10.2210/pdb4aqe/pdb
• Related: 2WBX 2WCP 2WD0 2WHV 4APX 4AQ8 4AQA
• Descriptor: CADHERIN-23, PROTOCADHERIN-15, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: cell adhesion, hearing, deafness, cdh23, pcdh15, heterophilic
• Biological source: MUS MUSCULUS (HOUSE MOUSE); More
• Cellular location: Cell membrane; Single-pass type I membrane protein (By similarity): Q99PF4 Q99PJ1
• Total number of polymer chains: 2
• Total formula weight: 51883.97

Authors

Sotomayor, M.,Weihofen, W.,Gaudet, R.,Corey, D.P. (deposition date: 2012-04-16, release date: 2012-11-07, Last modification date: 2023-12-20)

• Primary citation: Sotomayor, M.,Weihofen, W.,Gaudet, R.,Corey, D.P.; Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction; Nature, 492:128-, 2012; PubMed: 23135401; DOI: 10.1038/NATURE11590

Experimental method

X-RAY DIFFRACTION (2.27 Å)