7E4L
Conversion of pyrophosphate-dependent myo-inositol-1 kinase into myo-inositol-3 kinase by N78L/S89L mutation
Summary for 7E4L
Entry DOI | 10.2210/pdb7e4l/pdb |
Descriptor | PfkB domain-containing protein, METHYLENEDIPHOSPHONIC ACID, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | pyrophosphate-dependent kinase, transferase |
Biological source | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) |
Total number of polymer chains | 2 |
Total formula weight | 64660.19 |
Authors | Tashiro, R.,Miki, K.,Fujihashi, M. (deposition date: 2021-02-14, release date: 2021-05-05, Last modification date: 2023-11-29) |
Primary citation | Tashiro, R.,Sato, T.,Atomi, H.,Miki, K.,Fujihashi, M. Altering the Phosphorylation Position of Pyrophosphate-Dependent myo -Inositol-1-Kinase Based on Its Crystal Structure. Acs Chem.Biol., 16:794-799, 2021 Cited by PubMed: 33877806DOI: 10.1021/acschembio.0c00733 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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