7E4L
Conversion of pyrophosphate-dependent myo-inositol-1 kinase into myo-inositol-3 kinase by N78L/S89L mutation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | PfkB domain-containing protein | polymer | 286 | 32129.8 | 2 | UniProt (R4NYE9) Pfam (PF00294) UniProt (by SIFTS) (Q9WYP6) In PDB | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) | pyrophosphate-dependent myo-inositol-1 kinase |
2 | A, B | METHYLENEDIPHOSPHONIC ACID | non-polymer | 176.0 | 2 | Chemie (MDN) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 286 (UniProt: R4NYE9)
PDB | External Database | Details |
---|---|---|
Leu 78 | Asn 78 | engineered mutation |
Leu 89 | Ser 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 64259.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 400.6 | |
All* | Total formula weight | 64660.2 |