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PDB: 27201 件

8EXK
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Crystal structure of PTP1B D181A/Q262A phosphatase domain with JAK2 activation loop phosphopeptide
分子名称: PHOSPHATE ION, Tyrosine-protein kinase JAK2 activation loop peptide, Tyrosine-protein phosphatase non-receptor type 1
著者Morris, R, Kershaw, N.J, Babon, J.J.
登録日2022-10-25
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Structure guided studies of the interaction between PTP1B and JAK.
Commun Biol, 6, 2023
8TU1
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The Capsid of Porcine Bocavirus 1
分子名称: VP2
著者Velez, M, Mietzsch, M, McKenna, R.
登録日2023-08-15
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.31 Å)
主引用文献Structural Characterization of Canine Minute Virus, Rat and Porcine Bocavirus.
Viruses, 15, 2023
8F3Q
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Crystal structure of Penicillin Binding Protein 5 (PBP5) Y460A variant apo form from Enterococcus faecium
分子名称: Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Schoenle, M.V, Choy, M.S, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
1HH5
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cytochrome c7 from Desulfuromonas acetoxidans
分子名称: CYTOCHROME C7, HEME C
著者Czjzek, M, Haser, R, Arnoux, P, Shepard, W.
登録日2000-12-21
公開日2001-05-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of Cytochrome C7 from Desulfuromonas Acetoxidans at 1.9A Resolutio N
Acta Crystallogr.,Sect.D, 57, 2001
8TU0
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The Capsid of Canine Minute Virus
分子名称: VP2
著者Velez, M, Mietzsch, M, McKenna, R.
登録日2023-08-15
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Structural Characterization of Canine Minute Virus, Rat and Porcine Bocavirus.
Viruses, 15, 2023
6GFA
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Structure of Nucleotide binding domain of HSP110, ATP and Mg2+ complexed
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 105 kDa, MAGNESIUM ION
著者Gonzalez, D, Gotthard, G, Gozzi, G.J, Seigneuric, R, Neiers, F, Briand, L, Garrido, C.
登録日2018-04-29
公開日2019-05-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy.
Cell Death Differ., 27, 2020
6QZQ
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BU of 6qzq by Molmil
Crystal structure of Csx1 from Sulfolobus islandicus monoclinic form
分子名称: CRISPR-associated (Cas) DxTHG family
著者Molina, R, Montoya, G, Sofos, N, Stella, S.
登録日2019-03-12
公開日2020-01-22
最終更新日2020-08-05
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of Csx1-cOA4complex reveals the basis of RNA decay in Type III-B CRISPR-Cas.
Nat Commun, 10, 2019
4ZOB
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BU of 4zob by Molmil
Crystal Structure of beta-glucosidase from Listeria innocua in complex with gluconolactone
分子名称: D-glucono-1,5-lactone, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Nakajima, M, Yoshida, R, Miyanaga, A, Abe, K, Takahashi, Y, Sugimoto, N, Toyoizumi, H, Nakai, H, Kitaoka, M, Taguchi, H.
登録日2015-05-06
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Functional and Structural Analysis of a beta-Glucosidase Involved in beta-1,2-Glucan Metabolism in Listeria innocua
Plos One, 11, 2016
6QMA
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Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in nanodisc (intermediate state)
分子名称: CALCIUM ION, Predicted protein
著者Kalienkova, V, Clerico Mosina, V, Bryner, L, Oostergetel, G.T, Dutzler, R, Paulino, C.
登録日2019-02-01
公開日2019-03-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM.
Elife, 8, 2019
3ZE7
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3D structure of the Ni-Fe-Se hydrogenase from D. vulgaris Hildenborough in the reduced state at 1.95 Angstroms
分子名称: CARBONMONOXIDE-(DICYANO) IRON, FE (II) ION, HYDROSULFURIC ACID, ...
著者Marques, M.C, Coelho, R, Pereira, I.A.C, Matias, P.M.
登録日2012-12-03
公開日2013-06-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Redox State-Dependent Changes in the Crystal Structure of [Nifese] Hydrogenase from Desulfovibrio Vulgaris Hildenborough
Int.J.Hydrogen Energy, 38, 2013
8U1J
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N-Terminal domain of DNA-Damage Response Protein C (DdrC) from Deinococcus radiodurans - Crystal form xMJ7102
分子名称: DNA damage response protein C
著者Szabla, R, Song, Y, Junop, M.S.
登録日2023-09-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Full-length dimer of DNA-Damage Response Protein C from Deinococcus radiodurans
To Be Published
1H68
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BU of 1h68 by Molmil
sensory rhodopsin II
分子名称: CHLORIDE ION, RETINAL, SENSORY RHODOPSIN II
著者Royant, A, Nollert, P, Edman, K, Neutze, R, Landau, E.M, Pebay-Peyroula, E, Navarro, J.
登録日2001-06-08
公開日2001-08-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-Ray Structure of Sensory Rhodopsin II at 2.1 A Resolution
Proc.Natl.Acad.Sci.USA, 98, 2001
4WYG
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BU of 4wyg by Molmil
Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis complexed with a fragment hit
分子名称: 1,2-ETHANEDIOL, 1-{4-[(4-chloro-1H-pyrazol-1-yl)methyl]phenyl}methanamine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Dai, R, Finzel, B.C.
登録日2014-11-17
公開日2015-07-08
最終更新日2015-07-22
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Fragment-Based Exploration of Binding Site Flexibility in Mycobacterium tuberculosis BioA.
J.Med.Chem., 58, 2015
4WUR
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The crystal structure of the MERS-CoV papain-like protease (C111S) with human ubiquitin
分子名称: ISOPROPYL ALCOHOL, Papain-like protease, Polyubiquitin-B, ...
著者Lei, J, Hilgenfeld, R.
登録日2014-11-03
公開日2014-11-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin.
Virol Sin, 31, 2016
6QP6
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BU of 6qp6 by Molmil
Cryo-EM structure of calcium-bound mTMEM16F lipid scramblase in digitonin
分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-6, CALCIUM ION
著者Alvadia, C, Lim, N.K, Clerico Mosina, V, Oostergetel, G.T, Dutzler, R, Paulino, C.
登録日2019-02-13
公開日2019-03-06
最終更新日2019-04-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F.
Elife, 8, 2019
4WWH
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BU of 4wwh by Molmil
CRYSTAL STRUCTURE OF AN ABC TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM MYCOBACTERIUM SMEGMATIS (MSMEG_1704, TARGET EFI-510967) WITH BOUND D-GALACTOSE
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ABC transporter, beta-D-galactopyranose
著者Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2014-11-11
公開日2014-11-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献CRYSTAL STRUCTURE OF AN ABC TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM MYCOBACTERIUM SMEGMATIS (MSMEG_1704, TARGET EFI-510967) WITH BOUND D-GALACTOSE
To be published
4JZF
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Structure of factor VIIA in complex with the inhibitor 2-{2-[(3-carbamoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid
分子名称: 2-{2-[(3-carbamoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid, CALCIUM ION, Factor VIIa (Heavy Chain), ...
著者Wei, A, Anumula, R.
登録日2013-04-02
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold.
Bioorg.Med.Chem.Lett., 23, 2013
3SM3
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BU of 3sm3 by Molmil
Crystal Structure of SAM-dependent methyltransferases Q8PUK2_METMA from Methanosarcina mazei. Northeast Structural Genomics Consortium Target MaR262.
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, SAM-dependent methyltransferases
著者Vorobiev, S, Neely, H, Seetharaman, J, Snyder, A, Patel, P, Xiao, R, Ciccosanti, C, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2011-06-27
公開日2011-07-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.197 Å)
主引用文献Crystal Structure of SAM-dependent methyltransferases Q8PUK2_METMA from Methanosarcina mazei.
To be Published, 2009
1GTQ
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BU of 1gtq by Molmil
6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE
分子名称: 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE, ZINC ION
著者Nar, H, Huber, R, Heizmann, C.W, Thoeny, B, Buergisser, D.
登録日1995-09-16
公開日1996-04-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Three-dimensional structure of 6-pyruvoyl tetrahydropterin synthase, an enzyme involved in tetrahydrobiopterin biosynthesis.
EMBO J., 13, 1994
1GRL
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THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS
分子名称: GROEL (HSP60 CLASS)
著者Braig, K, Otwinowski, Z, Hegde, R, Boisvert, D.C, Joachimiak, A, Horwich, A.L, Sigler, P.B.
登録日1995-03-07
公開日1995-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of the bacterial chaperonin GroEL at 2.8 A.
Nature, 371, 1994
8EP1
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BU of 8ep1 by Molmil
Eag Kv channel with voltage sensor in the down conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EOW
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BU of 8eow by Molmil
Eag Kv channel with voltage sensor in the up conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
4X2D
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Clostridium difficile Fic protein_0569 mutant S31A, E35A in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Fic family protein putative filamentation induced by cAMP protein, MAGNESIUM ION
著者Jorgensen, R, Dedic, E.
登録日2014-11-26
公開日2015-12-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Clostridium difficile Fic_0569 S31A, E35A mutant at 1.8 Angstroms resolution
To Be Published
1GTG
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Crystal structure of the thermostable serine-carboxyl type proteinase, kumamolysin (kscp)
分子名称: CALCIUM ION, KUMAMOLYSIN
著者Comellas-Bigler, M, Fuentes-Prior, P, Maskos, K, Huber, R, Oyama, H, Uchida, K, Dunn, B.M, Oda, K, Bode, W.
登録日2002-01-15
公開日2002-06-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase
Structure, 10, 2002
4X3E
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Crystal structure of EED in complex with a trimethylated Jarid2 peptide
分子名称: ALA-GLN-ARG-M3L-PHE-ALA-GLN-SER, Polycomb protein EED
著者Justin, N, Gamblin, S.J, Margueron, R.
登録日2014-11-28
公開日2015-01-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.
Mol.Cell, 57, 2015

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件を2024-07-17に公開中

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