4XGZ
| Crystal structure of human paxillin LD2 motif in complex with Fab fragment | 分子名称: | 1,2-ETHANEDIOL, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ... | 著者 | Nocula-Lugowska, M, Lugowski, M, Salgia, R, Kossiakoff, A.A. | 登録日 | 2015-01-04 | 公開日 | 2015-07-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin. J.Mol.Biol., 427, 2015
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4Y1L
| Ubc9 Homodimer The Missing Link in Poly-SUMO Chain Formation | 分子名称: | RWD domain-containing protein 3, SUMO-conjugating enzyme UBC9 | 著者 | Aileen, Y.A, Ambaye, N.D, Li, Y.J, Vega, R, Bzymek, K, Williams, J.C, Hu, W, Chen, Y. | 登録日 | 2015-02-08 | 公開日 | 2015-05-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | RWD Domain as an E2 (Ubc9)-Interaction Module. J.Biol.Chem., 290, 2015
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4Y29
| Identification of a novel PPARg ligand that regulates metabolism | 分子名称: | 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, Peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma | 著者 | Wang, R, Li, Y. | 登録日 | 2015-02-09 | 公開日 | 2015-09-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Selective targeting of PPAR gamma by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency. Sci Rep, 5, 2015
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6P10
| Structure of spastin AAA domain (N527C mutant) in complex with JNJ-7706621 inhibitor | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide, Drosophila melanogaster Spastin AAA domain, ... | 著者 | Pisa, R, Cupido, T, Kapoor, T.M. | 登録日 | 2019-05-17 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins. Cell Chem Biol, 26, 2019
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7PYA
| Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 3-Hydroxyazetidine hydrochloride | 分子名称: | Cholinephosphate cytidylyltransferase, azetidin-3-ol | 著者 | Duclovel, C, Gelin, M, Krimm, I, Cerdan, R, Guichou, J.-F. | 登録日 | 2021-10-09 | 公開日 | 2022-10-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors To Be Published
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7PV2
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6P5I
| Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1) | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | 著者 | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | 登録日 | 2019-05-30 | 公開日 | 2019-09-18 | 最終更新日 | 2020-02-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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1F80
| HOLO-(ACYL CARRIER PROTEIN) SYNTHASE IN COMPLEX WITH HOLO-(ACYL CARRIER PROTEIN) | 分子名称: | ACYL CARRIER PROTEIN, HOLO-(ACYL CARRIER PROTEIN) SYNTHASE, SODIUM ION | 著者 | Parris, K.D, Lin, L, Tam, A, Mathew, R, Hixon, J, Stahl, M, Fritz, C.C, Seehra, J, Somers, W.S. | 登録日 | 2000-06-28 | 公開日 | 2001-06-28 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites. Structure Fold.Des., 8, 2000
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7PY9
| Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with (pyrrolidin-2-yl)methanol | 分子名称: | Cholinephosphate cytidylyltransferase, D-Prolinol | 著者 | Duclovel, C, Gelin, M, Krimm, I, Cerdan, R, Guichou, J.-F. | 登録日 | 2021-10-09 | 公開日 | 2022-10-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors To Be Published
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6P4H
| Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 2) | 分子名称: | 18S rRNA, IAPV-IRES, RACK1, ... | 著者 | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | 登録日 | 2019-05-27 | 公開日 | 2019-09-18 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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4XI0
| MamA 41-end from Desulfovibrio magneticus RS-1 | 分子名称: | Magnetosome protein MamA | 著者 | Zarivach, R, Zeytuni, N, Cronin, S, Davidov, G, Baran, D, Stein, T. | 登録日 | 2015-01-06 | 公開日 | 2015-08-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | MamA as a Model Protein for Structure-Based Insight into the Evolutionary Origins of Magnetotactic Bacteria. Plos One, 10, 2015
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7PGQ
| GAP-SecPH region of human neurofibromin isoform 2 in closed conformation. | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Neurofibromin, ZINC ION | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | 登録日 | 2021-08-15 | 公開日 | 2022-10-26 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
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4XOA
| Crystal structure of a FimH*DsG complex from E.coli K12 in space group P1 | 分子名称: | FimG, Protein FimH | 著者 | Jakob, R.P, Eras, J, Glockshuber, R, Maier, T. | 登録日 | 2015-01-16 | 公開日 | 2016-01-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.541 Å) | 主引用文献 | Catch-bond mechanism of the bacterial adhesin FimH. Nat Commun, 7, 2016
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7PV4
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1FO5
| SOLUTION STRUCTURE OF REDUCED MJ0307 | 分子名称: | THIOREDOXIN | 著者 | Cave, J.W, Cho, H.S, Batchelder, A.M, Kim, R, Yokota, H, Wemmer, D.E, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2000-08-24 | 公開日 | 2001-04-11 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution nuclear magnetic resonance structure of a protein disulfide oxidoreductase from Methanococcus jannaschii. Protein Sci., 10, 2001
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7PYB
| Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 2-Hydroxypyridine | 分子名称: | 1~{H}-pyridin-2-one, Cholinephosphate cytidylyltransferase, Guanidinium | 著者 | Duclovel, C, Gelin, M, Krimm, I, Cerdan, R, Guichou, J.-F. | 登録日 | 2021-10-09 | 公開日 | 2022-10-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors To Be Published
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8RI5
| Crystal structure of transplatin/B-DNA adduct obtained upon 48 h of soaking | 分子名称: | AMMONIA, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, ... | 著者 | Tito, G, Troisi, R, Ferraro, G, Sica, F, Merlino, A. | 登録日 | 2023-12-18 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.415 Å) | 主引用文献 | On the mechanism of action of arsenoplatins: arsenoplatin-1 binding to a B-DNA dodecamer. Dalton Trans, 53, 2024
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3WII
| Crystal structure of the Fab fragment of B2212A, a murine monoclonal antibody specific for the third fibronectin domain (Fn3) of human ROBO1. | 分子名称: | anti-human ROBO1 antibody B2212A Fab heavy chain, anti-human ROBO1 antibody B2212A Fab light chain | 著者 | Nakayama, T, Mizohata, E, Yamashita, T, Nagatoishi, S, Nakakido, M, Iwanari, H, Mochizuki, Y, Kado, Y, Yokota, Y, Sato, R, Tsumoto, K, Fujitani, H, Kodama, T, Hamakubo, T, Inoue, T. | 登録日 | 2013-09-12 | 公開日 | 2015-01-21 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses Protein Sci., 24, 2015
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4XMX
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4XN5
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4XOE
| Crystal structure of a FimH*DsG complex from E.coli F18 with bound heptyl alpha-D-mannopyrannoside | 分子名称: | CACODYLATE ION, FimG protein, FimH protein, ... | 著者 | Jakob, R.P, Sauer, M.M, Navarra, G, Ernst, B, Glockshuber, R, Maier, T. | 登録日 | 2015-01-16 | 公開日 | 2016-01-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Catch-bond mechanism of the bacterial adhesin FimH. Nat Commun, 7, 2016
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7SSV
| Structure of human Kv1.3 with Fab-ShK fusion | 分子名称: | Fab-ShK fusion, heavy chain, light chain, ... | 著者 | Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R. | 登録日 | 2021-11-11 | 公開日 | 2022-06-29 | 最終更新日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
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1F9I
| CRYSTAL STRUCTURE OF THE PHOTOACTIVE YELLOW PROTEIN MUTANT Y42F | 分子名称: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | 著者 | Brudler, R, Meyer, T.E, Genick, U.K, Tollin, G, Getzoff, E.D. | 登録日 | 2000-07-10 | 公開日 | 2000-07-21 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Coupling of hydrogen bonding to chromophore conformation and function in photoactive yellow protein. Biochemistry, 39, 2000
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6P4G
| Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 1) | 分子名称: | 18S rRNA, IAPV-IRES, RACK1, ... | 著者 | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | 登録日 | 2019-05-27 | 公開日 | 2019-09-18 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6PJI
| HIV-1 Protease NL4-3 WT in Complex with LR3-43 | 分子名称: | Protease NL4-3, SULFATE ION, methyl [(1S)-1-cyclopropyl-2-({(2S,3S,5S)-5-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-1,6-diphenylhexan-2-yl}amino)-2-oxoethyl]carbamate | 著者 | Lockbaum, G.J, Rusere, L.N, Henes, M, Kosovrasti, K, Lee, S.K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. | 登録日 | 2019-06-28 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere. J.Med.Chem., 63, 2020
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