8RI5
Crystal structure of transplatin/B-DNA adduct obtained upon 48 h of soaking
Summary for 8RI5
Entry DOI | 10.2210/pdb8ri5/pdb |
Descriptor | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, AMMONIA, ... (5 entities in total) |
Functional Keywords | b-dna, dodecamer, dickerson, platinum, interaction, dna |
Biological source | DNA molecule |
Total number of polymer chains | 2 |
Total formula weight | 7563.20 |
Authors | Tito, G.,Troisi, R.,Ferraro, G.,Sica, F.,Merlino, A. (deposition date: 2023-12-18, release date: 2024-02-07, Last modification date: 2024-02-28) |
Primary citation | Troisi, R.,Tito, G.,Ferraro, G.,Sica, F.,Massai, L.,Geri, A.,Cirri, D.,Messori, L.,Merlino, A. On the mechanism of action of arsenoplatins: arsenoplatin-1 binding to a B-DNA dodecamer. Dalton Trans, 53:3476-3483, 2024 Cited by PubMed: 38270175DOI: 10.1039/d3dt04302a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.415 Å) |
Structure validation
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