4XGZ

Crystal structure of human paxillin LD2 motif in complex with Fab fragment

Summary for 4XGZ

• Entry DOI: 10.2210/pdb4xgz/pdb
• Related: 4XH2
• Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, PAXILLIN LD2, ... (6 entities in total)
• Functional Keywords: synthetic antibody, paxillin, ld motif, immunoglobulin, fab fragment, complex, focal adhesion, cell adhesion
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 36
• Total formula weight: 598042.16

Authors

Nocula-Lugowska, M.,Lugowski, M.,Salgia, R.,Kossiakoff, A.A. (deposition date: 2015-01-04, release date: 2015-07-01, Last modification date: 2023-09-27)

• Primary citation: Nocula-Lugowska, M.,Lugowski, M.,Salgia, R.,Kossiakoff, A.A.; Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.; J.Mol.Biol., 427:2532-2547, 2015; PubMed: 26087144; DOI: 10.1016/j.jmb.2015.06.004

Experimental method

X-RAY DIFFRACTION (2.5 Å)