4XGZ
Crystal structure of human paxillin LD2 motif in complex with Fab fragment
Summary for 4XGZ
Entry DOI | 10.2210/pdb4xgz/pdb |
Related | 4XH2 |
Descriptor | FAB HEAVY CHAIN, FAB LIGHT CHAIN, PAXILLIN LD2, ... (6 entities in total) |
Functional Keywords | synthetic antibody, paxillin, ld motif, immunoglobulin, fab fragment, complex, focal adhesion, cell adhesion |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 36 |
Total formula weight | 598042.16 |
Authors | Nocula-Lugowska, M.,Lugowski, M.,Salgia, R.,Kossiakoff, A.A. (deposition date: 2015-01-04, release date: 2015-07-01, Last modification date: 2023-09-27) |
Primary citation | Nocula-Lugowska, M.,Lugowski, M.,Salgia, R.,Kossiakoff, A.A. Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin. J.Mol.Biol., 427:2532-2547, 2015 Cited by PubMed: 26087144DOI: 10.1016/j.jmb.2015.06.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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