4XGZ

Crystal structure of human paxillin LD2 motif in complex with Fab fragment

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue NO3 B 301

Chain	Residue
B	ILE21
B	THR22
B	CYS23
B	ARG24
B	TYR87
B	CYS88
B	GLY99
B	GLY101

---

site_id	AC2
Number of Residues	9
Details	binding site for residue NO3 D 301

Chain	Residue
D	CYS23
D	ARG24
D	TRP35
D	TYR87
D	CYS88
D	GLY99
D	GLN100
D	GLY101
D	THR22

---

site_id	AC3
Number of Residues	8
Details	binding site for residue NO3 F 301

Chain	Residue
F	THR22
F	ARG24
F	TRP35
F	TYR87
F	CYS88
F	GLY99
F	GLN100
F	GLY101

---

site_id	AC4
Number of Residues	7
Details	binding site for residue NO3 I 301

Chain	Residue
I	CYS23
I	ARG24
I	TYR87
I	CYS88
I	GLY99
I	GLN100
I	GLY101

---

site_id	AC5
Number of Residues	10
Details	binding site for residue NO3 K 301

Chain	Residue
K	ILE21
K	THR22
K	CYS23
K	ARG24
K	TRP35
K	TYR87
K	CYS88
K	GLY99
K	GLN100
K	GLY101

---

site_id	AC6
Number of Residues	9
Details	binding site for residue NO3 L 301

Chain	Residue
L	ILE21
L	THR22
L	CYS23
L	ARG24
L	TYR86
L	TYR87
L	CYS88
L	GLY99
L	GLY101

---

site_id	AC7
Number of Residues	5
Details	binding site for residue EDO N 301

Chain	Residue
N	GLN37
N	LYS45
N	PHE62
N	GLU81
N	ASP82

---

site_id	AC8
Number of Residues	7
Details	binding site for residue NO3 N 302

Chain	Residue
N	THR22
N	CYS23
N	ARG24
N	TYR87
N	CYS88
N	GLY99
N	GLY101

---

site_id	AC9
Number of Residues	10
Details	binding site for residue NO3 P 301

Chain	Residue
P	ILE21
P	THR22
P	CYS23
P	ARG24
P	TRP35
P	TYR87
P	CYS88
P	GLY99
P	GLN100
P	GLY101

---

site_id	AD1
Number of Residues	5
Details	binding site for residue EDO Q 301

Chain	Residue
C	ARG19
C	GLN81
Q	GLY55
Q	THR57
Q	HOH402

---

site_id	AD2
Number of Residues	8
Details	binding site for residue NO3 R 301

Chain	Residue
R	THR22
R	ARG24
R	TRP35
R	TYR87
R	CYS88
R	GLY99
R	GLN100
R	GLY101

---

site_id	AD3
Number of Residues	8
Details	binding site for residue NO3 T 301

Chain	Residue
T	CYS23
T	ARG24
T	TRP35
T	TYR87
T	CYS88
T	GLY99
T	GLN100
T	GLY101

---

site_id	AD4
Number of Residues	10
Details	binding site for residue NO3 V 301

Chain	Residue
V	TYR86
V	CYS88
V	GLY99
V	GLN100
V	GLY101
V	ILE21
V	THR22
V	CYS23
V	ARG24
V	TRP35

---

site_id	AD5
Number of Residues	1
Details	binding site for residue EDO W 301

Chain	Residue
W	SER70

---

site_id	AD6
Number of Residues	7
Details	binding site for residue NO3 X 301

Chain	Residue
X	ILE21
X	ARG24
X	TYR87
X	CYS88
X	GLY99
X	GLN100
X	GLY101

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
A	TYR194-HIS200
B	TYR192-HIS198

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
a	SER3
s	SER3
u	SER3
w	SER3
c	SER3
e	SER3
g	SER3
h	SER3
j	SER3
m	SER3
o	SER3
q	SER3

---