8FW9
 
 | | Cryo-EM structure of full-length human NLRC4 inflammasome with C12 symmetry | | 分子名称: | NLR family CARD domain-containing protein 4 | | 著者 | Matico, R.E, Yu, X, Miller, R, Somani, S, Ricketts, M.D, Kumar, N, Steele, R.A, Medley, Q, Berger, S, Faustin, B, Sharma, S. | | 登録日 | 2023-01-20 | | 公開日 | 2024-01-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | | 主引用文献 | Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing.
Nat.Struct.Mol.Biol., 31, 2024
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8FTA
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8FW6
 | | Human Lactate Dehydrogenase A in Complex with Inhibitor CHK-336 | | 分子名称: | (2P)-2-{5-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | | 著者 | Lowther, W.T, Gumpena, R. | | 登録日 | 2023-01-20 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Human Lactate Dehydrogenase A in complex with inhibitor CHK-336
To Be Published
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1H4K
 | | Sulfurtransferase from Azotobacter vinelandii in complex with hypophosphite | | 分子名称: | 1,2-ETHANEDIOL, HYPOPHOSPHITE, SULFATE ION, ... | | 著者 | Bordo, D, Forlani, F, Spallarossa, A, Colnaghi, R, Carpen, A, Pagani, S, Bolognesi, M. | | 登録日 | 2001-05-11 | | 公開日 | 2002-05-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | A Persulfurated Cysteine Promotes Active Site Reactivity in Azotobacter Vinelandii Rhodanse
Biol.Chem., 382, 2001
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1H4M
 | | Sulfurtransferase from Azotobacter vinelandii in complex with phosphate | | 分子名称: | 1,2-ETHANEDIOL, PUTATIVE THIOSULFATE SULFURTRANSFERASE | | 著者 | Bordo, D, Forlani, F, Spallarossa, A, Colnaghi, R, Carpen, A, Pagani, S, Bolognesi, M. | | 登録日 | 2001-05-11 | | 公開日 | 2002-05-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Persulfurated Cysteine Promotes Active Site Reactivity in Azotobacter Vinelandii Rhodanse
Biol.Chem., 382, 2001
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3HVW
 | | Crystal Structure of the GGDEF domain of the PA2567 protein from Pseudomonas aeruginosa, Northeast Structural Genomics Consortium Target PaR365C | | 分子名称: | Diguanylate-cyclase (DGC) | | 著者 | Forouhar, F, Lew, S, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Foote, E.L, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-06-16 | | 公開日 | 2009-06-23 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Northeast Structural Genomics Consortium Target PaR365C
To be published
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8G1F
 | | Structure of ACLY-D1026A-products | | 分子名称: | (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Wei, X, Marmorstein, R. | | 登録日 | 2023-02-02 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
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1H9H
 | | COMPLEX OF EETI-II WITH PORCINE TRYPSIN | | 分子名称: | CALCIUM ION, TRYPSIN, TRYPSIN INHIBITOR II | | 著者 | Kraetzner, R, Wentzel, A, Kolmar, H, Uson, I. | | 登録日 | 2001-03-12 | | 公開日 | 2004-07-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of Ecballium Elaterium Trypsin Inhibitor II (Eeti-II): A Rigid Molecular Scaffold
Acta Crystallogr.,Sect.D, 61, 2005
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3HXP
 | | Crystal structure of the FhuD fold-family BSU3320, a periplasmic binding protein component of a Fep/Fec-like ferrichrome ABC transporter from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR577 | | 分子名称: | Iron(3+)-hydroxamate-binding protein fhuD | | 著者 | Forouhar, F, Neely, H, Seetharaman, J, Fang, F, Xiao, R, Cunningham, K, Ma, L, Chen, C.X, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-06-21 | | 公開日 | 2009-07-07 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Northeast Structural Genomics Consortium Target SR577
To be Published
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4YYP
 | | Crystal structure of human PLK4-PB3 in complex with STIL-CC | | 分子名称: | CHLORIDE ION, SCL-interrupting locus protein, Serine/threonine-protein kinase PLK4 | | 著者 | Imseng, S, Arquint, C, Gabryjonczyk, A, Boehm, R, Sauer, E, Hiller, S, Nigg, E.A, Maier, T. | | 登録日 | 2015-03-24 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | STIL binding to Polo-box 3 of PLK4 regulates centriole duplication.
Elife, 4, 2015
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8FWD
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8FYW
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8G2F
 | | Crystal Structure of PRMT3 with Compound II710 | | 分子名称: | 5'-S-[3-(N'-benzylcarbamimidamido)propyl]-5'-thioadenosine, Protein arginine N-methyltransferase 3 | | 著者 | Song, X, Dong, A, Deng, Y, Huang, R, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2023-02-03 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.
Acta Pharm Sin B, 13, 2023
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8FZN
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8G1E
 | | Structure of ACLY-D1026A-products-asym | | 分子名称: | (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Wei, X, Marmorstein, R. | | 登録日 | 2023-02-02 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
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4DO7
 | | Crystal structure of an amidohydrolase (cog3618) from burkholderia multivorans (target efi-500235) with bound zn, space group c2 | | 分子名称: | Amidohydrolase 2, SULFATE ION, ZINC ION | | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Seidel, R.D, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Al Obaidi, N.F, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Raushel, F.M, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2012-02-09 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of an amidohydrolase (cog3618) from burkholderia multivorans (target efi-500235) with bound zn, space group c2
to be published
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8FID
 | | Crystal Structure of Erwinia tracheiphila CYP114 in complex with ent-kaurenoic acid (Crystal Form 2) | | 分子名称: | (8alpha,9beta,10alpha,13alpha)-kaur-16-en-18-oic acid, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Stewart Jr, C.E, Nagel, R. | | 登録日 | 2022-12-16 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Dual factors required for cytochrome-P450-mediated hydrocarbon ring contraction in bacterial gibberellin phytohormone biosynthesis.
Proc.Natl.Acad.Sci.USA, 120, 2023
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2E3C
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8FIB
 | | Crystal Structure of Erwinia tracheiphila CYP114 | | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Stewart Jr, C.E, Nagel, R. | | 登録日 | 2022-12-16 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Dual factors required for cytochrome-P450-mediated hydrocarbon ring contraction in bacterial gibberellin phytohormone biosynthesis.
Proc.Natl.Acad.Sci.USA, 120, 2023
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1H9I
 | | COMPLEX OF EETI-II MUTANT WITH PORCINE TRYPSIN | | 分子名称: | CALCIUM ION, TRYPSIN, TRYPSIN INHIBITOR II | | 著者 | Kraetzner, R, Wentzel, A, Kolmar, H, Uson, I. | | 登録日 | 2001-03-12 | | 公開日 | 2004-07-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of Ecballium Elaterium Trypsin Inhibitor II (Eeti-II): A Rigid Molecular Scaffold
Acta Crystallogr.,Sect.D, 61, 2005
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8H6L
 | | Cryo-EM structure of human exon-defined spliceosome in the early B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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8H6K
 | | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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2OFQ
 | | NMR Solution Structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system | | 分子名称: | TraN, TraO | | 著者 | Harris, R, Bayliss, R, Driscoll, P.C, Waksman, G. | | 登録日 | 2007-01-04 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system
Proc.Natl.Acad.Sci.Usa, 104, 2007
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8H6E
 | | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-17 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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8IDZ
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