8FW6

Human Lactate Dehydrogenase A in Complex with Inhibitor CHK-336

Summary for 8FW6

• Entry DOI: 10.2210/pdb8fw6/pdb
• Descriptor: L-lactate dehydrogenase A chain, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, (2P)-2-{5-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, ... (6 entities in total)
• Functional Keywords: ldha hldha human lactate dehydrogenase a, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 78680.38

Authors

Lowther, W.T.,Gumpena, R. (deposition date: 2023-01-20, release date: 2024-01-24)

• Primary citation: Lowther, W.T.,Gumpena, R.; Human Lactate Dehydrogenase A in complex with inhibitor CHK-336; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.34 Å)