4JKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jku by Molmil](/molmil-images/mine/4jku) | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinaldic acid, NYSGRC Target 14306 | Descriptor: | ADENOSINE, DIMETHYL SULFOXIDE, Probable sugar kinase protein, ... | Authors: | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-03-11 | Release date: | 2013-03-27 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinaldic acid, NYSGRC Target 14306 To be Published
|
|
1QA3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qa3 by Molmil](/molmil-images/mine/1qa3) | TAILSPIKE PROTEIN, MUTANT A334I | Descriptor: | TAILSPIKE PROTEIN | Authors: | Baxa, U, Steinbacher, S, Weintraub, A, Huber, R, Seckler, R. | Deposit date: | 1999-04-10 | Release date: | 2000-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mutations improving the folding of phage P22 tailspike protein affect its receptor binding activity. J.Mol.Biol., 293, 1999
|
|
1JIC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jic by Molmil](/molmil-images/mine/1jic) | |
7LJ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lj9 by Molmil](/molmil-images/mine/7lj9) | |
1P8J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1p8j by Molmil](/molmil-images/mine/1p8j) | CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, ... | Authors: | Henrich, S, Cameron, A, Bourenkov, G.P, Kiefersauer, R, Huber, R, Lindberg, I, Bode, W, Than, M.E. | Deposit date: | 2003-05-07 | Release date: | 2003-07-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Crystal Structure of the Proprotein Processing Proteinase Furin Explains its Stringent Specificity Nat.Struct.Biol., 10, 2003
|
|
1L6Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1l6z by Molmil](/molmil-images/mine/1l6z) | CRYSTAL STRUCTURE OF MURINE CEACAM1A[1,4]: A CORONAVIRUS RECEPTOR AND CELL ADHESION MOLECULE IN THE CEA FAMILY | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, biliary glycoprotein C | Authors: | Tan, K, Zelus, B.D, Meijers, R, Liu, J.-H, Bergelson, J.M, Duke, N, Zhang, R, Joachimiak, A, Holmes, K.V, Wang, J.-H. | Deposit date: | 2002-03-14 | Release date: | 2002-09-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | CRYSTAL STRUCTURE OF MURINE sCEACAM1a[1,4]: A CORONAVIRUS RECEPTOR IN THE CEA FAMILY Embo J., 21, 2002
|
|
1LEA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lea by Molmil](/molmil-images/mine/1lea) | SOLUTION STRUCTURE OF THE LEXA REPRESSOR DNA BINDING DETERMINED BY 1H NMR SPECTROSCOPY | Descriptor: | LEXA REPRESSOR DNA BINDING DOMAIN | Authors: | Fogh, R.H, Ottleben, G, Rueterjans, H, Schnarr, M, Boelens, R, Kaptein, R. | Deposit date: | 1994-05-11 | Release date: | 1994-08-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the LexA repressor DNA binding domain determined by 1H NMR spectroscopy. EMBO J., 13, 1994
|
|
1OTT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ott by Molmil](/molmil-images/mine/1ott) | Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex | Descriptor: | CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... | Authors: | Dutzler, R, Campbell, E.B, MacKinnon, R. | Deposit date: | 2003-03-23 | Release date: | 2003-04-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
|
|
1YQJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yqj by Molmil](/molmil-images/mine/1yqj) | Crystal Structure of p38 Alpha in Complex with a Selective Pyridazine Inhibitor | Descriptor: | 6((S)-3-BENZYLPIPERAZIN-1-YL)-3-(NAPHTHALEN-2-YL)-4-(PYRIDIN-4-YL)PYRAZINE, Mitogen-activated protein kinase 14, SULFATE ION | Authors: | Tamayo, N, Liao, H, Goldberg, M, Syed, R, Li, V, Powers, D, Tudor, Y, Yu, V, Wong, M.L, Henkle, B, Middelton, S, Harvey, T, Jang, G, Hungate, R, Dominguez, C. | Deposit date: | 2005-02-01 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design and synthesis of potent pyridazine inhibitors of p38 MAP kinase. Bioorg.Med.Chem.Lett., 15, 2005
|
|
1L7B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1l7b by Molmil](/molmil-images/mine/1l7b) | Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT | Descriptor: | DNA LIGASE | Authors: | Sahota, G, Dixon, B.L, Huang, Y.P, Aramini, J, Monleon, D, Bhattacharya, D, Swapna, G.V.T, Yin, C, Xiao, R, Anderson, S, Tejero, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-03-14 | Release date: | 2003-09-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of the Brct Domain from Thermus Thermophilus DNA Ligase To be Published
|
|
4KAH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kah by Molmil](/molmil-images/mine/4kah) | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 4-bromo-1H-pyrazole | Descriptor: | 4-bromo-1H-pyrazole, ADENOSINE, BROMIDE ION, ... | Authors: | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-04-22 | Release date: | 2013-05-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 4-bromo-1H-pyrazole To be Published
|
|
4K8O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k8o by Molmil](/molmil-images/mine/4k8o) | CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645N, D651A MUTANT) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Antigen peptide transporter 1, CITRIC ACID, ... | Authors: | Vakkasoglu, A.S, Grossmann, N, Hulpke, S, Abele, R, Tampe, R, Gaudet, R. | Deposit date: | 2013-04-18 | Release date: | 2014-09-03 | Last modified: | 2014-12-03 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter. Nat Commun, 5, 2014
|
|
1TGC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tgc by Molmil](/molmil-images/mine/1tgc) | ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY | Descriptor: | CALCIUM ION, TRYPSINOGEN | Authors: | Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R. | Deposit date: | 1981-10-26 | Release date: | 1982-03-04 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography Acta Crystallogr.,Sect.B, 38, 1982
|
|
1SZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1szc by Molmil](/molmil-images/mine/1szc) | Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases | Descriptor: | CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, CHLORIDE ION, GLYCEROL, ... | Authors: | Zhao, K, Harshaw, R, Chai, X, Marmorstein, R. | Deposit date: | 2004-04-05 | Release date: | 2004-06-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases. Proc.Natl.Acad.Sci.Usa, 101, 2004
|
|
1QRB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qrb by Molmil](/molmil-images/mine/1qrb) | PLASTICITY AND STERIC STRAIN IN A PARALLEL BETA-HELIX: RATIONAL MUTATIONS IN P22 TAILSPIKE PROTEIN | Descriptor: | PROTEIN (TAILSPIKE-PROTEIN) | Authors: | Schuler, B, Furst, F, Osterroth, F, Steinbacher, S, Huber, R, Seckler, R. | Deposit date: | 1999-06-12 | Release date: | 2000-04-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Plasticity and steric strain in a parallel beta-helix: rational mutations in the P22 tailspike protein. Proteins, 39, 2000
|
|
294D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 294d by Molmil](/molmil-images/mine/294d) | INTERCALATED CYTOSINE MOTIF AND NOVEL ADENINE CLUSTERS IN THE CRYSTAL STRUCTURE OF TETRAHYMENA TELOMERE | Descriptor: | DNA (5'-D(*AP*AP*CP*CP*CP*C)-3') | Authors: | Cai, L, Chen, L, Raghavan, S, Ratliff, R, Moyzis, R, Rich, A. | Deposit date: | 1996-10-30 | Release date: | 1998-10-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Intercalated cytosine motif and novel adenine clusters in the crystal structure of the Tetrahymena telomere. Nucleic Acids Res., 26, 1998
|
|
1QQF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qqf by Molmil](/molmil-images/mine/1qqf) | N-TERMINALLY TRUNCATED C3D,G FRAGMENT OF THE COMPLEMENT SYSTEM | Descriptor: | PROTEIN (COMPLEMENT C3DG) | Authors: | Zanotti, G, Bassetto, A, Battistutta, R, Stoppini, M, Berni, R. | Deposit date: | 1999-06-04 | Release date: | 2000-07-31 | Last modified: | 2015-01-21 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure at 1.44 A resolution of an N-terminally truncated form of the rat serum complement C3d fragment. Biochim.Biophys.Acta, 1478, 2000
|
|
1Q7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1q7l by Molmil](/molmil-images/mine/1q7l) | Zn-binding domain of the T347G mutant of human aminoacylase-I | Descriptor: | Aminoacylase-1, GLYCINE, ZINC ION | Authors: | Lindner, H.A, Lunin, V.V, Alary, A, Hecker, R, Cygler, M, Menard, R. | Deposit date: | 2003-08-19 | Release date: | 2004-01-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family. J.Biol.Chem., 278, 2003
|
|
1J5A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1j5a by Molmil](/molmil-images/mine/1j5a) | STRUCTURAL BASIS FOR THE INTERACTION OF ANTIBIOTICS WITH THE PEPTIDYL TRANSFERASE CENTER IN EUBACTERIA | Descriptor: | 23S RRNA, CLARITHROMYCIN, MAGNESIUM ION, ... | Authors: | Schluenzen, F, Zarivach, R, Harms, J, Bashan, A, Tocilj, A, Albrecht, R, Yonath, A, Franceschi, F. | Deposit date: | 2002-03-06 | Release date: | 2002-03-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature, 413, 2001
|
|
1QRC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qrc by Molmil](/molmil-images/mine/1qrc) | TAILSPIKE PROTEIN, MUTANT W391A | Descriptor: | TAILSPIKE PROTEIN | Authors: | Schuler, B, Furst, F, Osterroth, F, Steinbacher, S, Huber, R, Seckler, R. | Deposit date: | 1999-06-13 | Release date: | 2000-04-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Plasticity and steric strain in a parallel beta-helix: rational mutations in the P22 tailspike protein. Proteins, 39, 2000
|
|
1JK3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jk3 by Molmil](/molmil-images/mine/1jk3) | Crystal structure of human MMP-12 (Macrophage Elastase) at true atomic resolution | Descriptor: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, MACROPHAGE METALLOELASTASE, ... | Authors: | Lang, R, Kocourek, A, Braun, M, Tschesche, H, Huber, R, Bode, W, Maskos, K. | Deposit date: | 2001-07-11 | Release date: | 2001-09-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure. J.Mol.Biol., 312, 2001
|
|
1JOY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1joy by Molmil](/molmil-images/mine/1joy) | SOLUTION STRUCTURE OF THE HOMODIMERIC DOMAIN OF ENVZ FROM ESCHERICHIA COLI BY MULTI-DIMENSIONAL NMR. | Descriptor: | PROTEIN (ENVZ_ECOLI) | Authors: | Tomomori, C, Tanaka, T, Dutta, R, Park, H, Saha, S.K, Zhu, Y, Ishima, R, Liu, D, Tong, K.I, Kurokawa, H, Qian, H, Inouye, M, Ikura, M. | Deposit date: | 1998-12-28 | Release date: | 2000-01-12 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ. Nat.Struct.Biol., 6, 1999
|
|
1JQ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jq7 by Molmil](/molmil-images/mine/1jq7) | HCMV protease dimer-interface mutant, S225Y complexed to Inhibitor BILC 408 | Descriptor: | ASSEMBLIN, N-(6-aminohexanoyl)-3-methyl-L-valyl-3-methyl-L-valyl-N~1~-[(2S,3S)-3-hydroxy-4-oxo-4-{[(1R)-1-phenylpropyl]amino}butan-2-yl]-N~4~,N~4~-dimethyl-L-aspartamide | Authors: | Batra, R, Khayat, R, Tong, L. | Deposit date: | 2001-08-03 | Release date: | 2001-09-12 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease. Nat.Struct.Biol., 8, 2001
|
|
5AP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ap6 by Molmil](/molmil-images/mine/5ap6) | Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DUAL SPECIFICITY PROTEIN KINASE TTK, ... | Authors: | Gurden, M.D, Westwood, I.M, Faisal, A, Naud, S, Cheung, K.M, McAndrew, C, Wood, A, Schmitt, J, Boxall, K, Mak, G, Workman, P, Burke, R, Hoelder, S, Blagg, J, van Montfort, R, Linardopoulos, S. | Deposit date: | 2015-09-14 | Release date: | 2015-09-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Naturally Occurring Mutations in the Mps1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer Res., 75, 2015
|
|
4GWB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gwb by Molmil](/molmil-images/mine/4gwb) | Crystal structure of putative Peptide methionine sulfoxide reductase from Sinorhizobium meliloti 1021 | Descriptor: | CALCIUM ION, CHLORIDE ION, Peptide methionine sulfoxide reductase MsrA 3 | Authors: | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Zenchek, W, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-09-01 | Release date: | 2012-09-19 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal structure of putative Peptide methionine sulfoxide reductase from Sinorhizobium meliloti 1021 To be Published
|
|