1Q7L
Zn-binding domain of the T347G mutant of human aminoacylase-I
Summary for 1Q7L
Entry DOI | 10.2210/pdb1q7l/pdb |
Descriptor | Aminoacylase-1, ZINC ION, GLYCINE, ... (5 entities in total) |
Functional Keywords | aminoacylase-1, catalysis, enzyme dimerization, site-directed mutagenesis, structure comparison, zinc, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q03154 Q03154 |
Total number of polymer chains | 4 |
Total formula weight | 65109.28 |
Authors | Lindner, H.A.,Lunin, V.V.,Alary, A.,Hecker, R.,Cygler, M.,Menard, R. (deposition date: 2003-08-19, release date: 2004-01-20, Last modification date: 2024-02-14) |
Primary citation | Lindner, H.A.,Lunin, V.V.,Alary, A.,Hecker, R.,Cygler, M.,Menard, R. Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family. J.Biol.Chem., 278:44496-44504, 2003 Cited by PubMed: 12933810DOI: 10.1074/jbc.M304233200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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