8B8R
| Complex of Echovirus 11 with its attaching receptor decay-accelerating factor (CD55) | Descriptor: | DECAY ACCELERATING FACTOR (CD55), SPHINGOSINE, VP1, ... | Authors: | Stuart, D.I, Ren, J, Zhou, D, Qin, L. | Deposit date: | 2022-10-04 | Release date: | 2022-12-07 | Last modified: | 2023-01-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Switching of Receptor Binding Poses between Closely Related Enteroviruses. Viruses, 14, 2022
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2NS2
| Crystal Structure of Spindlin1 | Descriptor: | PHOSPHATE ION, Spindlin-1 | Authors: | Zhao, Q, Qin, L, Jiang, F, Wu, B, Yue, W, Xu, F, Rong, Z, Yuan, H, Xie, X, Gao, Y, Bai, C, Bartlam, M. | Deposit date: | 2006-11-02 | Release date: | 2006-11-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation J.Biol.Chem., 282, 2007
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5T1A
| Structure of CC Chemokine Receptor 2 with Orthosteric and Allosteric Antagonists | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2~{R})-1-(4-chloranyl-2-fluoranyl-phenyl)-2-cyclohexyl-3-ethanoyl-4-oxidanyl-2~{H}-pyrrol-5-one, (3S)-1-{(1S,2R,4R)-4-[methyl(propan-2-yl)amino]-2-propylcyclohexyl}-3-{[6-(trifluoromethyl)quinazolin-4-yl]amino}pyrrolidin-2-one, ... | Authors: | Zheng, Y, Qin, L, Ortiz Zacarias, N.V, de Vries, H, Han, G.W, Gustavsson, M, Dabros, M, Zhao, C, Cherney, R.J, Carter, P, Stamos, D, Abagyan, R, Cherezov, V, Stevens, R.C, IJzerman, A.P, Heitman, L.H, Tebben, A, Kufareva, I, Handel, T.M. | Deposit date: | 2016-08-18 | Release date: | 2016-12-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.806 Å) | Cite: | Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists. Nature, 540, 2016
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3OGG
| Crystal structure of the receptor binding domain of botulinum neurotoxin D | Descriptor: | Botulinum neurotoxin type D | Authors: | Zhang, Y, Gao, X, Qin, L, Buchko, G.W, Robinson, H, Varnum, S.M. | Deposit date: | 2010-08-16 | Release date: | 2010-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.651 Å) | Cite: | Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D. Biochem.Biophys.Res.Commun., 401, 2010
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3OMA
| Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with K362M mutation | Descriptor: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | Authors: | Liu, J, Qin, L, Ferguson-Miller, S. | Deposit date: | 2010-08-26 | Release date: | 2011-02-02 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump. Proc.Natl.Acad.Sci.USA, 108, 2011
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3OMI
| Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with D132A mutation | Descriptor: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | Authors: | Liu, J, Qin, L, Ferguson-Miller, S. | Deposit date: | 2010-08-27 | Release date: | 2011-02-02 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump. Proc.Natl.Acad.Sci.USA, 108, 2011
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3OMN
| Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with D132A mutation in the reduced state | Descriptor: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | Authors: | Liu, J, Qin, L, Ferguson-Miller, S. | Deposit date: | 2010-08-27 | Release date: | 2011-02-02 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump. Proc.Natl.Acad.Sci.USA, 108, 2011
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3OM3
| Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with K362M mutation in the reduced state | Descriptor: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | Authors: | Liu, J, Qin, L, Ferguson-Miller, S. | Deposit date: | 2010-08-26 | Release date: | 2011-02-02 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump. Proc.Natl.Acad.Sci.USA, 108, 2011
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5URM
| Crystal structure of human BRR2 in complex with T-1206548 | Descriptor: | 3-(5-{[(2R)-5-amino-2-cyclohexyl-7-oxo-2,3-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-yl]methyl}furan-2-yl)benzoic acid, U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Klein, M.G, Tjhen, R, Qin, L. | Deposit date: | 2017-02-11 | Release date: | 2017-07-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J. Med. Chem., 60, 2017
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5URJ
| Crystal structure of human BRR2 in complex with T-3905516 | Descriptor: | 6-benzyl-3-[(2R)-2-(3-fluoropyridin-2-yl)-6-methyl-3,4-dihydro-2H-1-benzopyran-7-yl]-4,6-dihydropyrido[4,3-d]pyrimidine-2,7(3H,8H)-dione, GLYCEROL, U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Klein, M.G, Tjhen, R, Qin, L. | Deposit date: | 2017-02-10 | Release date: | 2017-07-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J. Med. Chem., 60, 2017
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5XK4
| Retracted state of S65-phosphorylated ubiquitin | Descriptor: | Polyubiquitin-B | Authors: | Dong, X, Gong, Z, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C. | Deposit date: | 2017-05-05 | Release date: | 2017-06-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XK5
| Relaxed state of S65-phosphorylated ubiquitin | Descriptor: | Polyubiquitin-B | Authors: | Xu, D, Zhou, G, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C. | Deposit date: | 2017-05-05 | Release date: | 2017-06-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1WDG
| crystal structure of MHV spike protein fusion core | Descriptor: | E2 glycoprotein | Authors: | Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z. | Deposit date: | 2004-05-14 | Release date: | 2004-06-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE J.Biol.Chem., 279, 2004
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1WDF
| crystal structure of MHV spike protein fusion core | Descriptor: | E2 glycoprotein | Authors: | Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z. | Deposit date: | 2004-05-14 | Release date: | 2004-06-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE J.Biol.Chem., 279, 2004
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3PME
| Crystal structure of the receptor binding domain of botulinum neurotoxin C/D mosaic serotype | Descriptor: | GLYCEROL, SULFATE ION, Type C neurotoxin | Authors: | Zhang, Y, Buchko, G.W, Qin, L, Robinson, H, Varnum, S.M, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2010-11-16 | Release date: | 2010-12-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Crystal structure of the receptor binding domain of the botulinum C-D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions. Biochem.Biophys.Res.Commun., 404, 2011
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4NJL
| Crystal structure of middle east respiratory syndrome coronavirus S2 protein fusion core | Descriptor: | S protein, TRIETHYLENE GLYCOL | Authors: | Zhu, Y, Lu, L, Qin, L, Ye, S, Jiang, S, Zhang, R. | Deposit date: | 2013-11-10 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor. Nat Commun, 5, 2014
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6IYZ
| Structural basis for activity of TRIC counter-ion channels in calcium release | Descriptor: | CHLORIDE ION, Trimeric intracellular cation channel type A | Authors: | Wang, X.H, Zeng, Y, Qin, L, Gao, F, Su, M, Chen, Y.H. | Deposit date: | 2018-12-18 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
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5HXG
| STM1697-FlhD complex | Descriptor: | Flagellar transcriptional regulator FlhD, Uncharacterized protein STM1697 | Authors: | Li, B, Yuan, Z, Qin, L, Gu, L. | Deposit date: | 2016-01-30 | Release date: | 2017-02-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Crystal structure of STM1697-FlhD complex To Be Published
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5HXF
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7EN0
| Structure and Activity of SLAC1 Channels for Stomatal Signaling in Leaves | Descriptor: | DIUNDECYL PHOSPHATIDYL CHOLINE, SLow Anion Channel 1, SPHINGOSINE | Authors: | Deng, Y, Kashtoh, H, Wang, Q, Zhen, G, Li, Q, Tang, L, Gao, H, Zhang, C, Qin, L, Su, M, Li, F, Huang, X, Wang, Y, Xie, Q, Clarke, O.B, Hendrickson, W.A, Chen, Y. | Deposit date: | 2021-04-15 | Release date: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structure and activity of SLAC1 channels for stomatal signaling in leaves. Proc.Natl.Acad.Sci.USA, 118, 2021
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4R4L
| Crystal structure of wt cGMP dependent protein kinase I alpha (PKGI alpha) leucine zipper | Descriptor: | HEXANE-1,6-DIOL, SULFATE ION, cGMP-dependent protein kinase 1 | Authors: | Reger, A.S, Guo, E, Yang, M.P, Qin, L, Kim, C. | Deposit date: | 2014-08-19 | Release date: | 2015-09-23 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.245 Å) | Cite: | Structures of cGMP-Dependent Protein Kinase (PKG) I alpha Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability. Biochemistry, 54, 2015
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4R4M
| Crystal structure of C42L cGMP dependent protein kinase I alpha (PKGI alpha) leucine zipper | Descriptor: | SULFATE ION, cGMP-dependent protein kinase 1 | Authors: | Reger, A.S, Guo, E, Yang, M.P, Qin, L, Kim, C. | Deposit date: | 2014-08-19 | Release date: | 2015-09-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.922 Å) | Cite: | Structures of cGMP-Dependent Protein Kinase (PKG) I alpha Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability. Biochemistry, 54, 2015
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5UIW
| Crystal Structure of CC Chemokine Receptor 5 (CCR5) in complex with high potency HIV entry inhibitor 5P7-CCL5 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, C-C chemokine receptor type 5,Rubredoxin chimera, C-C motif chemokine 5, ... | Authors: | Zheng, Y, Qin, L, Han, G.W, Gustavsson, M, Kawamura, T, Stevens, R.C, Cherezov, V, Kufareva, I, Handel, T.M. | Deposit date: | 2017-01-15 | Release date: | 2017-06-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV. Immunity, 46, 2017
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5USG
| 5-Se-T2/4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant | Descriptor: | DNA (5'-D(*AP*(T5S)P*GP*(T5S)P*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ... | Authors: | Fang, Z, Qin, L, Huang, Z. | Deposit date: | 2017-02-13 | Release date: | 2017-03-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate Chemistryselect, 8, 2023
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5USA
| 5-Se-T2-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant | Descriptor: | DNA (5'-D(*AP*(T5S)P*GP*TP*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ... | Authors: | Fang, Z, Qin, L, Huang, Z. | Deposit date: | 2017-02-13 | Release date: | 2017-03-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate Chemistryselect, 8, 2023
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