5USA

5-Se-T2-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant

Summary for 5USA

• Entry DOI: 10.2210/pdb5usa/pdb
• Related: 5US2 5USE 5USG
• Descriptor: RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), DNA (5'-D(*AP*(T5S)P*GP*TP*CP*G)-3'), Ribonuclease H, ... (5 entities in total)
• Functional Keywords: hydrolase - rna - dna complex, hydrolase / rna / dna
• Biological source: Bacillus halodurans; More
• Cellular location: Cytoplasm : Q9KEI9
• Total number of polymer chains: 3
• Total formula weight: 20156.47

Authors

Fang, Z.,Qin, L.,Huang, Z. (deposition date: 2017-02-13, release date: 2017-03-08, Last modification date: 2024-05-22)

• Primary citation: Fang, Z.,Dantsu, Y.,Chen, C.,Zhang, W.,Huang, Z.; Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate; Chemistryselect, 8:-, 2023; DOI: 10.1002/slct.202302253

Experimental method

X-RAY DIFFRACTION (1.8 Å)