5HXF

Crystal structure of 3C protease from a mild Human enterovirus 71 in complex with rupintrivir

Summary for 5HXF

• Entry DOI: 10.2210/pdb5hxf/pdb
• Descriptor: 3C protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, SULFATE ION, ... (4 entities in total)
• Functional Keywords: enterovirus, hydrolase
• Biological source: Enterovirus A71 (EV71)
• Cellular location: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Virion : A0A0M3PZC0
• Total number of polymer chains: 1
• Total formula weight: 21086.06

Authors

Li, B.,Yuan, Z.,Qin, L.,Gu, L. (deposition date: 2016-01-30, release date: 2017-02-15, Last modification date: 2023-11-08)

• Primary citation: Li, B.,Yue, Y.,Zhang, Y.,Yuan, Z.,Liu, Y.,Li, P.,Song, N.,Li, Z.,Gu, L.,Qin, L.; Crystal structure of 3C protease from a mild Human enterovirus 71 in complex with rupintrivir; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.39 Å)