4R4M

Crystal structure of C42L cGMP dependent protein kinase I alpha (PKGI alpha) leucine zipper

Summary for 4R4M

• Entry DOI: 10.2210/pdb4r4m/pdb
• Related: 1ZXA 3NMD 4OJK 4R4L
• Descriptor: cGMP-dependent protein kinase 1, SULFATE ION (3 entities in total)
• Functional Keywords: leucine zipper, kinase, binding domain, mypt1, rhoa, dna binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : Q13976
• Total number of polymer chains: 3
• Total formula weight: 17768.59

Authors

Reger, A.S.,Guo, E.,Yang, M.P.,Qin, L.,Kim, C. (deposition date: 2014-08-19, release date: 2015-09-23, Last modification date: 2024-04-03)

• Primary citation: Qin, L.,Reger, A.S.,Guo, E.,Yang, M.P.,Zwart, P.,Casteel, D.E.,Kim, C.; Structures of cGMP-Dependent Protein Kinase (PKG) I alpha Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability.; Biochemistry, 54:4419-4422, 2015; PubMed: 26132214; DOI: 10.1021/acs.biochem.5b00572

Experimental method

X-RAY DIFFRACTION (1.922 Å)