4NJL
 
 | | Crystal structure of middle east respiratory syndrome coronavirus S2 protein fusion core | | 分子名称: | S protein, TRIETHYLENE GLYCOL | | 著者 | Zhu, Y, Lu, L, Qin, L, Ye, S, Jiang, S, Zhang, R. | | 登録日 | 2013-11-10 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor.
Nat Commun, 5, 2014
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1WDF
 | | crystal structure of MHV spike protein fusion core | | 分子名称: | E2 glycoprotein | | 著者 | Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z. | | 登録日 | 2004-05-14 | | 公開日 | 2004-06-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE
J.Biol.Chem., 279, 2004
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1WDG
 | | crystal structure of MHV spike protein fusion core | | 分子名称: | E2 glycoprotein | | 著者 | Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z. | | 登録日 | 2004-05-14 | | 公開日 | 2004-06-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE
J.Biol.Chem., 279, 2004
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5T1A
 | | Structure of CC Chemokine Receptor 2 with Orthosteric and Allosteric Antagonists | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2~{R})-1-(4-chloranyl-2-fluoranyl-phenyl)-2-cyclohexyl-3-ethanoyl-4-oxidanyl-2~{H}-pyrrol-5-one, (3S)-1-{(1S,2R,4R)-4-[methyl(propan-2-yl)amino]-2-propylcyclohexyl}-3-{[6-(trifluoromethyl)quinazolin-4-yl]amino}pyrrolidin-2-one, ... | | 著者 | Zheng, Y, Qin, L, Ortiz Zacarias, N.V, de Vries, H, Han, G.W, Gustavsson, M, Dabros, M, Zhao, C, Cherney, R.J, Carter, P, Stamos, D, Abagyan, R, Cherezov, V, Stevens, R.C, IJzerman, A.P, Heitman, L.H, Tebben, A, Kufareva, I, Handel, T.M. | | 登録日 | 2016-08-18 | | 公開日 | 2016-12-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | | 主引用文献 | Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.
Nature, 540, 2016
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8B9F
 | | Structure of Echovirus 11 complexed with DAF (CD55) calculated from symmetry expansion | | 分子名称: | Complement decay-accelerating factor, Genome polyprotein, SPHINGOSINE | | 著者 | Stuart, D.I, Ren, J, Qin, L, Zhou, D. | | 登録日 | 2022-10-05 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-01-04 | | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | | 主引用文献 | Switching of Receptor Binding Poses between Closely Related Enteroviruses.
Viruses, 14, 2022
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8B8R
 | | Complex of Echovirus 11 with its attaching receptor decay-accelerating factor (CD55) | | 分子名称: | DECAY ACCELERATING FACTOR (CD55), SPHINGOSINE, VP1, ... | | 著者 | Stuart, D.I, Ren, J, Zhou, D, Qin, L. | | 登録日 | 2022-10-04 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-01-04 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Switching of Receptor Binding Poses between Closely Related Enteroviruses.
Viruses, 14, 2022
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3OGG
 | | Crystal structure of the receptor binding domain of botulinum neurotoxin D | | 分子名称: | Botulinum neurotoxin type D | | 著者 | Zhang, Y, Gao, X, Qin, L, Buchko, G.W, Robinson, H, Varnum, S.M. | | 登録日 | 2010-08-16 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | | 主引用文献 | Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D.
Biochem.Biophys.Res.Commun., 401, 2010
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3OMI
 | | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with D132A mutation | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | | 著者 | Liu, J, Qin, L, Ferguson-Miller, S. | | 登録日 | 2010-08-27 | | 公開日 | 2011-02-02 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3OMA
 | | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with K362M mutation | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | | 著者 | Liu, J, Qin, L, Ferguson-Miller, S. | | 登録日 | 2010-08-26 | | 公開日 | 2011-02-02 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3OM3
 | | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with K362M mutation in the reduced state | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | | 著者 | Liu, J, Qin, L, Ferguson-Miller, S. | | 登録日 | 2010-08-26 | | 公開日 | 2011-02-02 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3OMN
 | | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with D132A mutation in the reduced state | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | | 著者 | Liu, J, Qin, L, Ferguson-Miller, S. | | 登録日 | 2010-08-27 | | 公開日 | 2011-02-02 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
Proc.Natl.Acad.Sci.USA, 108, 2011
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1BXD
 | | NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (OSMOLARITY SENSOR PROTEIN (ENVZ)) | | 著者 | Tanaka, T, Saha, S.K, Tomomori, C, Ishima, R, Liu, D, Tong, K.I, Park, H, Dutta, R, Qin, L, Swindells, M.B, Yamazaki, T, Ono, A.M, Kainosho, M, Inouye, M, Ikura, M. | | 登録日 | 1998-10-02 | | 公開日 | 1999-10-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ.
Nature, 396, 1998
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3PME
 | | Crystal structure of the receptor binding domain of botulinum neurotoxin C/D mosaic serotype | | 分子名称: | GLYCEROL, SULFATE ION, Type C neurotoxin | | 著者 | Zhang, Y, Buchko, G.W, Qin, L, Robinson, H, Varnum, S.M, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2010-11-16 | | 公開日 | 2010-12-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Crystal structure of the receptor binding domain of the botulinum C-D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions.
Biochem.Biophys.Res.Commun., 404, 2011
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5HXF
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2NS2
 | | Crystal Structure of Spindlin1 | | 分子名称: | PHOSPHATE ION, Spindlin-1 | | 著者 | Zhao, Q, Qin, L, Jiang, F, Wu, B, Yue, W, Xu, F, Rong, Z, Yuan, H, Xie, X, Gao, Y, Bai, C, Bartlam, M. | | 登録日 | 2006-11-02 | | 公開日 | 2006-11-28 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation
J.Biol.Chem., 282, 2007
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5HXG
 | | STM1697-FlhD complex | | 分子名称: | Flagellar transcriptional regulator FlhD, Uncharacterized protein STM1697 | | 著者 | Li, B, Yuan, Z, Qin, L, Gu, L. | | 登録日 | 2016-01-30 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | | 主引用文献 | Crystal structure of STM1697-FlhD complex
To Be Published
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5URJ
 | | Crystal structure of human BRR2 in complex with T-3905516 | | 分子名称: | 6-benzyl-3-[(2R)-2-(3-fluoropyridin-2-yl)-6-methyl-3,4-dihydro-2H-1-benzopyran-7-yl]-4,6-dihydropyrido[4,3-d]pyrimidine-2,7(3H,8H)-dione, GLYCEROL, U5 small nuclear ribonucleoprotein 200 kDa helicase | | 著者 | Klein, M.G, Tjhen, R, Qin, L. | | 登録日 | 2017-02-10 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2.
J. Med. Chem., 60, 2017
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5URM
 | | Crystal structure of human BRR2 in complex with T-1206548 | | 分子名称: | 3-(5-{[(2R)-5-amino-2-cyclohexyl-7-oxo-2,3-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-yl]methyl}furan-2-yl)benzoic acid, U5 small nuclear ribonucleoprotein 200 kDa helicase | | 著者 | Klein, M.G, Tjhen, R, Qin, L. | | 登録日 | 2017-02-11 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2.
J. Med. Chem., 60, 2017
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6IYZ
 | | Structural basis for activity of TRIC counter-ion channels in calcium release | | 分子名称: | CHLORIDE ION, Trimeric intracellular cation channel type A | | 著者 | Wang, X.H, Zeng, Y, Qin, L, Gao, F, Su, M, Chen, Y.H. | | 登録日 | 2018-12-18 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for activity of TRIC counter-ion channels in calcium release.
Proc.Natl.Acad.Sci.USA, 116, 2019
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4R4L
 | | Crystal structure of wt cGMP dependent protein kinase I alpha (PKGI alpha) leucine zipper | | 分子名称: | HEXANE-1,6-DIOL, SULFATE ION, cGMP-dependent protein kinase 1 | | 著者 | Reger, A.S, Guo, E, Yang, M.P, Qin, L, Kim, C. | | 登録日 | 2014-08-19 | | 公開日 | 2015-09-23 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | | 主引用文献 | Structures of cGMP-Dependent Protein Kinase (PKG) I alpha Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability.
Biochemistry, 54, 2015
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4R4M
 | | Crystal structure of C42L cGMP dependent protein kinase I alpha (PKGI alpha) leucine zipper | | 分子名称: | SULFATE ION, cGMP-dependent protein kinase 1 | | 著者 | Reger, A.S, Guo, E, Yang, M.P, Qin, L, Kim, C. | | 登録日 | 2014-08-19 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.922 Å) | | 主引用文献 | Structures of cGMP-Dependent Protein Kinase (PKG) I alpha Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability.
Biochemistry, 54, 2015
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7EN0
 | | Structure and Activity of SLAC1 Channels for Stomatal Signaling in Leaves | | 分子名称: | DIUNDECYL PHOSPHATIDYL CHOLINE, SLow Anion Channel 1, SPHINGOSINE | | 著者 | Deng, Y, Kashtoh, H, Wang, Q, Zhen, G, Li, Q, Tang, L, Gao, H, Zhang, C, Qin, L, Su, M, Li, F, Huang, X, Wang, Y, Xie, Q, Clarke, O.B, Hendrickson, W.A, Chen, Y. | | 登録日 | 2021-04-15 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structure and activity of SLAC1 channels for stomatal signaling in leaves.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5UIW
 | | Crystal Structure of CC Chemokine Receptor 5 (CCR5) in complex with high potency HIV entry inhibitor 5P7-CCL5 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, C-C chemokine receptor type 5,Rubredoxin chimera, C-C motif chemokine 5, ... | | 著者 | Zheng, Y, Qin, L, Han, G.W, Gustavsson, M, Kawamura, T, Stevens, R.C, Cherezov, V, Kufareva, I, Handel, T.M. | | 登録日 | 2017-01-15 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | | 主引用文献 | Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV.
Immunity, 46, 2017
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5USG
 | | 5-Se-T2/4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant | | 分子名称: | DNA (5'-D(*AP*(T5S)P*GP*(T5S)P*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ... | | 著者 | Fang, Z, Qin, L, Huang, Z. | | 登録日 | 2017-02-13 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Chemistryselect, 8, 2023
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5USA
 | | 5-Se-T2-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant | | 分子名称: | DNA (5'-D(*AP*(T5S)P*GP*TP*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ... | | 著者 | Fang, Z, Qin, L, Huang, Z. | | 登録日 | 2017-02-13 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Chemistryselect, 8, 2023
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