8WFY
| The Crystal Structure of SHP2 from Biortus. | Descriptor: | 6-(4-azanyl-4-methyl-piperidin-1-yl)-3-[2,3-bis(chloranyl)phenyl]pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | Deposit date: | 2023-09-20 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Crystal Structure of SHP2 from Biortus. To Be Published
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8X5M
| The Crystal Structure of JNK1 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, 3-[4-(dimethylamino)butanoylamino]-~{N}-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide, GLYCEROL, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | Deposit date: | 2023-11-17 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Crystal Structure of JNK1 from Biortus. To Be Published
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5XEB
| Structure of the envelope glycoprotein of Dhori virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein | Authors: | Peng, R, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2017-04-03 | Release date: | 2017-10-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Structures of human-infectingThogotovirusfusogens support a common ancestor with insect baculovirus Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6LXK
| Crystal structure of Z2B3 D102R Fab in complex with influenza virus neuraminidase from A/Serbia/NS-601/2014 (H1N1) | Descriptor: | CALCIUM ION, Heavy chain of Z2B3-D102R Fab, Light chain of Z2B3-D102R Fab, ... | Authors: | Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y. | Deposit date: | 2020-02-11 | Release date: | 2020-12-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.608 Å) | Cite: | Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus. Mbio, 11, 2020
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5XLA
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8X5J
| The Crystal Structure of PARP5A from Biortus. | Descriptor: | 1,2-ETHANEDIOL, L(+)-TARTARIC ACID, Poly [ADP-ribose] polymerase, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B. | Deposit date: | 2023-11-17 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Crystal Structure of PARP5A from Biortus. To Be Published
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5JYY
| Structure-based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-resistant Influenza Viruses | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-[(2-methoxyethyl)carbamoyl]-D-glycero-D-galacto-non-2-enon ic acid, CALCIUM ION, ... | Authors: | Fu, L, Wu, Y, Bi, Y, Zhang, S, Lv, X, Qi, J, Li, Y, Lu, X, Yan, J, Gao, G.F, Li, X. | Deposit date: | 2016-05-15 | Release date: | 2016-06-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses J.Med.Chem., 59, 2016
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6LUQ
| Haloperidol bound D2 dopamine receptor structure inspired discovery of subtype selective ligands | Descriptor: | 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one, OLEIC ACID, chimera of D(2) dopamine receptor and Endolysin | Authors: | Fan, L, Tan, L, Chen, Z, Qi, J, Nie, F, Luo, Z, Cheng, J, Wang, S. | Deposit date: | 2020-01-30 | Release date: | 2020-03-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Haloperidol bound D2dopamine receptor structure inspired the discovery of subtype selective ligands. Nat Commun, 11, 2020
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8XFM
| The Crystal Structure of MNK2 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, 5-(3-azanyl-1~{H}-indazol-6-yl)-1-[(3-chlorophenyl)methyl]pyridin-2-one, MAP kinase-interacting serine/threonine-protein kinase 2, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | Deposit date: | 2023-12-14 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Crystal Structure of MNK2 from Biortus. To Be Published
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8XFL
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6KUJ
| Structure of influenza D virus polymerase bound to cRNA promoter in class 1 | Descriptor: | 3'-cRNA promoter, 5'-cRNA promoter, Polymerase 3, ... | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | Deposit date: | 2019-09-02 | Release date: | 2019-10-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of influenza D virus polymerase bound to cRNA promoter in Mode A conformation NAT NANOTECHNOL, 2019
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8WU2
| Crystal structure of RNA-dependent RNA polymerases from Jingmen tick virus | Descriptor: | RNA polymerase, SELENIUM ATOM | Authors: | Liu, Z, Han, P, Peng, Q, Qi, J. | Deposit date: | 2023-10-20 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of RNA-dependent RNA polymerases from Jingmen tick virus and Alongshan virus HLIFE, 2, 2024
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5XJ4
| Complex structure of durvalumab-scFv/PD-L1 | Descriptor: | Programmed cell death 1 ligand 1, durvalumab-VH, durvalumab-VL | Authors: | Tan, S, Liu, K, Chai, Y, Gao, G.F, Qi, J. | Deposit date: | 2017-04-29 | Release date: | 2018-04-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab Protein Cell, 9, 2018
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8XU4
| The Crystal Structure of MAPK2 from Biortus. | Descriptor: | MALONIC ACID, MAP kinase-activated protein kinase 2 | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z. | Deposit date: | 2024-01-12 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The Crystal Structure of MAPK2 from Biortus. To Be Published
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8XPX
| The Crystal Structure of PARP12 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Wang, F, Cheng, W, Lv, Z, Qi, J, Shen, Z. | Deposit date: | 2024-01-04 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The Crystal Structure of PARP12 from Biortus. To Be Published
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8XN6
| The Crystal Structure of GSK3b from Biortus. | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glycogen synthase kinase-3 beta, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B. | Deposit date: | 2023-12-29 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Crystal Structure of GSK3b from Biortus. To Be Published
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8YHH
| The Crystal Structure of Mitotic Kinesin Eg5 from Biortus | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Wang, F, Cheng, W, Lv, Z, Qi, J, Wu, B. | Deposit date: | 2024-02-28 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Crystal Structure of Mitotic Kinesin Eg5 from Biortus To Be Published
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5JHM
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8X5K
| The Crystal Structure of SYK from Biortus. | Descriptor: | 1,2-ETHANEDIOL, 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide, Tyrosine-protein kinase SYK | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z. | Deposit date: | 2023-11-17 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Crystal Structure of SYK from Biortus. To Be Published
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3AL4
| Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | Authors: | Zhang, W, Qi, J.X, Shi, Y, Li, Q, Yan, J.H, Gao, G.F. | Deposit date: | 2010-07-22 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.872 Å) | Cite: | Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus Protein Cell, 1, 2010
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3UYW
| Crystal structures of globular head of 2009 pandemic H1N1 hemagglutinin | Descriptor: | 2-AMINOETHANESULFONIC ACID, Hemagglutinin | Authors: | Xuan, C.L, Shi, Y, Qi, J.X, Xiao, H.X, Gao, G.F. | Deposit date: | 2011-12-06 | Release date: | 2012-10-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | Structural vaccinology: structure-based design of influenza A virus hemagglutinin subtype-specific subunit vaccines Protein Cell, 2, 2011
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6KY8
| Crystal structure of ASFV dUTPase | Descriptor: | E165R | Authors: | Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F. | Deposit date: | 2019-09-17 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target. Mbio, 10, 2019
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6KY9
| Crystal structure of ASFV dUTPase and UMP complex | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R | Authors: | Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F. | Deposit date: | 2019-09-17 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target. Mbio, 10, 2019
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7YV8
| Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with golden hamster ACE2 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike glycoprotein, ... | Authors: | Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F. | Deposit date: | 2022-08-18 | Release date: | 2023-07-19 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
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8YHI
| The Crystal Structure of SHP1 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 6 | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z. | Deposit date: | 2024-02-28 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The Crystal Structure of SHP1 from Biortus. To Be Published
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