6TIW
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![BU of 6tiw by Molmil](/molmil-images/mine/6tiw) | Human kinesin-5 motor domain in the GSK state bound to microtubules (Conformation 2) | Descriptor: | 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... | Authors: | Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | Deposit date: | 2019-11-22 | Release date: | 2020-03-04 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
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6TA3
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![BU of 6ta3 by Molmil](/molmil-images/mine/6ta3) | Human kinesin-5 motor domain in the GSK-1 state bound to microtubules (Conformation 1) | Descriptor: | 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... | Authors: | Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | Deposit date: | 2019-10-29 | Release date: | 2020-04-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
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6TA4
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![BU of 6ta4 by Molmil](/molmil-images/mine/6ta4) | Human kinesin-5 motor domain in the AMPPNP state bound to microtubules | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ... | Authors: | Pena, A.P, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | Deposit date: | 2019-10-29 | Release date: | 2020-03-04 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
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5WDU
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![BU of 5wdu by Molmil](/molmil-images/mine/5wdu) | HIV-1 Env BG505 SOSIP.664 H72C-H564C trimer in complex with bNAbs PGT122 Fab, 35O22 Fab and NIH45-46 scFv | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Julien, J.-P, Torrents de la Pena, A, Sanders, R.W, Wilson, I.A. | Deposit date: | 2017-07-06 | Release date: | 2018-04-04 | Last modified: | 2022-11-30 | Method: | X-RAY DIFFRACTION (7 Å) | Cite: | Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization. Cell Rep, 20, 2017
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6NIJ
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![BU of 6nij by Molmil](/molmil-images/mine/6nij) | PGT145 Fab in complex with full length AMC011 HIV-1 Env | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 Glycoprotein 120, ... | Authors: | Cottrell, C.A, Torrents de la Pena, A, Rantalainen, K, Torres, J.L, Ward, A.B. | Deposit date: | 2018-12-29 | Release date: | 2019-07-31 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics. Plos Pathog., 15, 2019
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7SCO
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![BU of 7sco by Molmil](/molmil-images/mine/7sco) | Structure of H1 influenza hemagglutinin bound to Fab 310-39G10 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 310-39G10 Fab, ... | Authors: | Torrents de la Pena, A, Ward, A.B. | Deposit date: | 2021-09-28 | Release date: | 2022-08-24 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus. Immunity, 55, 2022
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7SCN
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![BU of 7scn by Molmil](/molmil-images/mine/7scn) | |
6EF0
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![BU of 6ef0 by Molmil](/molmil-images/mine/6ef0) | Yeast 26S proteasome bound to ubiquitinated substrate (1D* motor state) | Descriptor: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | Authors: | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | Deposit date: | 2018-08-15 | Release date: | 2018-10-17 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.43 Å) | Cite: | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. Science, 362, 2018
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6EF2
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![BU of 6ef2 by Molmil](/molmil-images/mine/6ef2) | Yeast 26S proteasome bound to ubiquitinated substrate (5T motor state) | Descriptor: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | Authors: | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | Deposit date: | 2018-08-15 | Release date: | 2018-10-17 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.27 Å) | Cite: | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. Science, 362, 2018
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6EF3
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![BU of 6ef3 by Molmil](/molmil-images/mine/6ef3) | Yeast 26S proteasome bound to ubiquitinated substrate (4D motor state) | Descriptor: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | Authors: | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | Deposit date: | 2018-08-15 | Release date: | 2018-10-17 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (4.17 Å) | Cite: | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. Science, 362, 2018
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7T6X
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![BU of 7t6x by Molmil](/molmil-images/mine/7t6x) | Cryo-EM structure of full-length hepatitis C virus E1E2 glycoprotein in complex with AR4A, AT12009, and IGH505 Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AR4A Fab, ... | Authors: | Torrents de la Pena, A, Ward, A.B, Eshun-Wilson, L, Lander, G.C. | Deposit date: | 2021-12-14 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (3.83 Å) | Cite: | Structure of the hepatitis C virus E1E2 glycoprotein complex. Science, 378, 2022
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5C8L
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![BU of 5c8l by Molmil](/molmil-images/mine/5c8l) | Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NudF protein, ... | Authors: | Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M. | Deposit date: | 2015-06-25 | Release date: | 2016-01-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus. Plos One, 10, 2015
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5C7T
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![BU of 5c7t by Molmil](/molmil-images/mine/5c7t) | Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase in complex with ADP-ribose | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5-DIPHOSPHORIBOSE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M. | Deposit date: | 2015-06-24 | Release date: | 2016-01-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus. Plos One, 10, 2015
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6EF1
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![BU of 6ef1 by Molmil](/molmil-images/mine/6ef1) | Yeast 26S proteasome bound to ubiquitinated substrate (5D motor state) | Descriptor: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | Authors: | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | Deposit date: | 2018-08-15 | Release date: | 2018-10-17 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.73 Å) | Cite: | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. Science, 362, 2018
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5C7Q
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![BU of 5c7q by Molmil](/molmil-images/mine/5c7q) | Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M. | Deposit date: | 2015-06-24 | Release date: | 2016-01-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus. Plos One, 10, 2015
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6XMJ
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![BU of 6xmj by Molmil](/molmil-images/mine/6xmj) | Human 20S proteasome bound to an engineered 11S (PA26) activator | Descriptor: | Proteasome activator protein PA26, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | Authors: | de la Pena, A.H, Opoku-Nsiah, K.A, Williams, S.K, Chopra, N, Sali, A, Gestwicki, J.E, Lander, G.C. | Deposit date: | 2020-06-30 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The Y Phi motif defines the structure-activity relationships of human 20S proteasome activators. Nat Commun, 13, 2022
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7L8A
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![BU of 7l8a by Molmil](/molmil-images/mine/7l8a) | BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-1 from animal Rh.33104 (Wk26 time point) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... | Authors: | Antanasijevic, A, Sewall, L.M, Torrents de la Pena, A, Ward, A.B. | Deposit date: | 2020-12-31 | Release date: | 2021-08-04 | Last modified: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun, 12, 2021
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7JSV
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![BU of 7jsv by Molmil](/molmil-images/mine/7jsv) | Cryo-EM structure of conjugative pili from carbapenem-resistant Klebsiella pneumoniae | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, Pilin | Authors: | Zheng, W, Pena, A, Frankel, G, Egelman, E.H. | Deposit date: | 2020-08-16 | Release date: | 2020-09-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryoelectron-Microscopic Structure of the pKpQIL Conjugative Pili from Carbapenem-Resistant Klebsiella pneumoniae. Structure, 28, 2020
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6ZPH
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![BU of 6zph by Molmil](/molmil-images/mine/6zph) | Kinesin binding protein complexed with Kif15 motor domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KIF-binding protein, Kinesin-like protein KIF15, ... | Authors: | Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. | Deposit date: | 2020-07-08 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | The mechanism of kinesin inhibition by kinesin-binding protein. Elife, 9, 2020
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6ZPI
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![BU of 6zpi by Molmil](/molmil-images/mine/6zpi) | Microtubule complexed with Kif15 motor domain. Symmetrised asymmetric unit | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF15, ... | Authors: | Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. | Deposit date: | 2020-07-08 | Release date: | 2020-12-30 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | The mechanism of kinesin inhibition by kinesin-binding protein. Elife, 9, 2020
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6ZPG
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![BU of 6zpg by Molmil](/molmil-images/mine/6zpg) | Kinesin binding protein (KBP) | Descriptor: | KIF-binding protein | Authors: | Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. | Deposit date: | 2020-07-08 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | The mechanism of kinesin inhibition by kinesin-binding protein. Elife, 9, 2020
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