Yeast 26S proteasome bound to ubiquitinated substrate (5D motor state)

Summary for 6EF1

Related6EF1 6EF2 6EF3 6EF0
EMDB information9043 9044 9045 9042
DescriptorProteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... (16 entities in total)
Functional Keywords26s proteasome, atpase, aaa+, protease, motor protein, ubiquitin
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Total number of polymer chains14
Total molecular weight369082.49
de la Pena, A.H.,Goodall, E.A.,Gates, S.N.,Lander, G.C.,Martin, A. (deposition date: 2018-08-15, release date: 2018-10-17, Last modification date: 2020-01-08)
Primary citation
de la Pena, A.H.,Goodall, E.A.,Gates, S.N.,Lander, G.C.,Martin, A.
Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 362:-, 2018
PubMed: 30309908 (PDB entries with the same primary citation)
DOI: 10.1126/science.aav0725
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers7 0.0% 0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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PDB entries from 2020-10-28