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6EF1

Yeast 26S proteasome bound to ubiquitinated substrate (5D motor state)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AProteasome subunit alpha type-1polymer23926909.61UniProt (P21243)
Pfam (PF10584)
Pfam (PF00227)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein
2BProteasome subunit alpha type-2polymer25027191.81UniProt (P23639)
Pfam (PF10584)
Pfam (PF00227)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7
3CProteasome subunit alpha type-3polymer23826313.61UniProt (P23638)
Pfam (PF10584)
Pfam (PF00227)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13
4DProteasome subunit alpha type-4polymer23426098.51UniProt (P40303)
Pfam (PF10584)
Pfam (PF00227)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6
5EProteasome subunit alpha type-5polymer24226544.81UniProt (P32379)
Pfam (PF00227)
Pfam (PF10584)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2
6FProteasome subunit alpha type-6polymer23325502.81UniProt (P40302)
Pfam (PF10584)
Pfam (PF00227)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5
7GProbable proteasome subunit alpha type-7polymer24326835.41UniProt (P21242)
Pfam (PF10584)
Pfam (PF00227)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1
8H26S proteasome regulatory subunit 7 homologpolymer26229070.61UniProt (P33299)
Pfam (PF00004)
Pfam (PF17862)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein CIM5,Tat-binding homolog 3
9I26S proteasome regulatory subunit 4 homologpolymer27130125.61UniProt (P40327)
Pfam (PF00004)
Pfam (PF17862)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Tat-binding homolog 5
10J26S proteasome regulatory subunit 8 homologpolymer27330239.31UniProt (Q01939)
Pfam (PF00004)
Pfam (PF17862)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein CIM3,Protein SUG1,Tat-binding protein TBY1
11K26S proteasome regulatory subunit 6B homologpolymer27630792.01UniProt (P33298)
Pfam (PF00004)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein YNT1,Tat-binding homolog 2
12L26S proteasome subunit RPT4polymer27130174.71UniProt (P53549)
Pfam (PF00004)
Pfam (PF17862)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)26S protease subunit SUG2,Proteasomal cap subunit
13M26S proteasome regulatory subunit 6Apolymer26228942.01UniProt (P33297)
Pfam (PF00004)
Pfam (PF17862)
In PDB
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Tat-binding protein homolog 1,TBP-1
14smodel substrate polypeptidepolymer151458.61UniProt (by SIFTS) (P07818)
In PDB
Homo sapiens (Human)
15H, I, J, KADENOSINE-5'-TRIPHOSPHATEnon-polymer507.24Chemie (ATP)
16L, MADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains14
Total formula weight366199.4
Non-Polymers*Number of molecules6
Total formula weight2883.1
All*Total formula weight369082.5
*Water molecules are not included.

217705

PDB entries from 2024-03-27

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