6XMJ
Human 20S proteasome bound to an engineered 11S (PA26) activator
Summary for 6XMJ
Entry DOI | 10.2210/pdb6xmj/pdb |
EMDB information | 22259 |
Descriptor | Proteasome subunit alpha type-6, Proteasome subunit beta type-3, Proteasome subunit beta type-2, ... (15 entities in total) |
Functional Keywords | 11s-bound, 20s proteasome, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 21 |
Total formula weight | 523664.12 |
Authors | de la Pena, A.H.,Opoku-Nsiah, K.A.,Williams, S.K.,Chopra, N.,Sali, A.,Gestwicki, J.E.,Lander, G.C. (deposition date: 2020-06-30, release date: 2020-07-22, Last modification date: 2024-05-15) |
Primary citation | Opoku-Nsiah, K.A.,de la Pena, A.H.,Williams, S.K.,Chopra, N.,Sali, A.,Lander, G.C.,Gestwicki, J.E. The Y Phi motif defines the structure-activity relationships of human 20S proteasome activators. Nat Commun, 13:1226-1226, 2022 Cited by PubMed: 35264557DOI: 10.1038/s41467-022-28864-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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