2B3P
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![BU of 2b3p by Molmil](/molmil-images/mine/2b3p) | Crystal structure of a superfolder green fluorescent protein | Descriptor: | ACETIC ACID, CADMIUM ION, green fluorescent protein | Authors: | Pedelacq, J.D, Cabantous, S, Tran, T.H, Terwilliger, T.C, Waldo, G.S. | Deposit date: | 2005-09-20 | Release date: | 2005-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Engineering and characterization of a superfolder green fluorescent protein. Nat.Biotechnol., 24, 2006
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2B3Q
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![BU of 2b3q by Molmil](/molmil-images/mine/2b3q) | Crystal structure of a well-folded variant of green fluorescent protein | Descriptor: | MAGNESIUM ION, green fluorescent protein | Authors: | Pedelacq, J.D, Cabantous, S, Tran, T.H, Terwilliger, T.C, Waldo, G.S. | Deposit date: | 2005-09-20 | Release date: | 2005-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Engineering and characterization of a superfolder green fluorescent protein. Nat.Biotechnol., 24, 2006
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1PVL
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![BU of 1pvl by Molmil](/molmil-images/mine/1pvl) | STRUCTURE OF THE PANTON-VALENTINE LEUCOCIDIN F COMPONENT FROM STAPHYLOCOCCUS AUREUS | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LEUCOCIDIN | Authors: | Pedelacq, J.D, Mourey, L, Maveyraud, L, Prevost, G, Samama, J.P. | Deposit date: | 1999-01-12 | Release date: | 1999-06-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of a Staphylococcus aureus leucocidin component (LukF-PV) reveals the fold of the water-soluble species of a family of transmembrane pore-forming toxins. Structure Fold.Des., 7, 1999
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1XQI
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![BU of 1xqi by Molmil](/molmil-images/mine/1xqi) | Crystal Structure Analysis of an NDP kinase from Pyrobaculum aerophilum | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nucleoside diphosphate kinase, TRIETHYLENE GLYCOL | Authors: | Pedelacq, J.D, Waldo, G.S, Cabantous, S, Liong, E.C, Berendzen, J, Terwilliger, T.C. | Deposit date: | 2004-10-12 | Release date: | 2005-09-20 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and functional features of an NDP kinase from the hyperthermophile crenarchaeon Pyrobaculum aerophilum Protein Sci., 14, 2005
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4U89
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![BU of 4u89 by Molmil](/molmil-images/mine/4u89) | |
4OOC
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![BU of 4ooc by Molmil](/molmil-images/mine/4ooc) | |
6HXU
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![BU of 6hxu by Molmil](/molmil-images/mine/6hxu) | Crystal structure of Human RHOB Q63L in complex with GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rho-related GTP-binding protein RhoB | Authors: | Soulie, S, Gence, R, Cabantous, S, Lajoie-Mazenc, I, Favre, G, Pedelacq, J.D. | Deposit date: | 2018-10-18 | Release date: | 2019-09-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | A Targeted Protein Degradation Cell-Based Screening for Nanobodies Selective toward the Cellular RHOB GTP-Bound Conformation. Cell Chem Biol, 26, 2019
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6QYG
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![BU of 6qyg by Molmil](/molmil-images/mine/6qyg) | |
6QYF
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![BU of 6qyf by Molmil](/molmil-images/mine/6qyf) | |
6QWU
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![BU of 6qwu by Molmil](/molmil-images/mine/6qwu) | 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 5.5 with Mn2+ and CoA. | Descriptor: | COENZYME A, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | Authors: | Nguyen, M.C, Mourey, L, Pedelacq, J.D. | Deposit date: | 2019-03-06 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
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6QXQ
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6QXR
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![BU of 6qxr by Molmil](/molmil-images/mine/6qxr) | 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 8.5 with Mn2+ and CoA. | Descriptor: | CALCIUM ION, COENZYME A, MANGANESE (II) ION, ... | Authors: | Nguyen, M.C, Mourey, L, Pedelacq, J.D. | Deposit date: | 2019-03-07 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
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4OKI
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![BU of 4oki by Molmil](/molmil-images/mine/4oki) | |
5L84
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![BU of 5l84 by Molmil](/molmil-images/mine/5l84) | |
8QZJ
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8QZI
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![BU of 8qzi by Molmil](/molmil-images/mine/8qzi) | Crystal structure of PptT-ACP from Mycobacterium tuberculosis | Descriptor: | 4'-phosphopantetheinyl transferase PptT, COENZYME A, ISOPROPYL ALCOHOL, ... | Authors: | Gavalda, S, Mourey, L, Pedelacq, J.D. | Deposit date: | 2023-10-27 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases Acs Catalysis, 14, 2024
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8QZH
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![BU of 8qzh by Molmil](/molmil-images/mine/8qzh) | Crystal structure of apo-PptT from Mycobacterium tuberculosis | Descriptor: | 4'-phosphopantetheinyl transferase PptT, ACETATE ION, MAGNESIUM ION | Authors: | Gavalda, S, Carivenc, C, Mourey, L, Pedelacq, J.D. | Deposit date: | 2023-10-27 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases Acs Catalysis, 14, 2024
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5NJI
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![BU of 5nji by Molmil](/molmil-images/mine/5nji) | Structure of the dehydratase domain of PpsC from Mycobacterium tuberculosis in complex with C12:1-CoA | Descriptor: | Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsC, ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (~{E})-dodec-2-enethioate | Authors: | Gavalda, S, Faille, A, Mourey, L, Pedelacq, J.D. | Deposit date: | 2017-03-28 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases. J. Mol. Biol., 429, 2017
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1AVB
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![BU of 1avb by Molmil](/molmil-images/mine/1avb) | ARCELIN-1 FROM PHASEOLUS VULGARIS L | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARCELIN-1, ... | Authors: | Mourey, L, Pedelacq, J.D, Fabre, C, Rouge, P, Samama, J.P. | Deposit date: | 1997-09-15 | Release date: | 1998-10-14 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the arcelin-1 dimer from Phaseolus vulgaris at 1.9-A resolution. J.Biol.Chem., 273, 1998
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6SGE
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![BU of 6sge by Molmil](/molmil-images/mine/6sge) | Crystal structure of Human RHOB-GTP in complex with nanobody B6 | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nanobody B6, ... | Authors: | Soulie, S, Gence, R, Cabantous, S, Lajoie-Mazenc, I, Favre, G, Pedelacq, J.D. | Deposit date: | 2019-08-04 | Release date: | 2019-09-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A Targeted Protein Degradation Cell-Based Screening for Nanobodies Selective toward the Cellular RHOB GTP-Bound Conformation. Cell Chem Biol, 26, 2019
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6RCX
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![BU of 6rcx by Molmil](/molmil-images/mine/6rcx) | Mycobacterial 4'-phosphopantetheinyl transferase PptAb in complex with the ACP domain of PpsC. | Descriptor: | CACODYLATE ION, COENZYME A, MANGANESE (II) ION, ... | Authors: | Nguyen, M.C, Mourey, L, Pedelacq, J.D. | Deposit date: | 2019-04-12 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
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1BT5
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![BU of 1bt5 by Molmil](/molmil-images/mine/1bt5) | CRYSTAL STRUCTURE OF THE IMIPENEM INHIBITED TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI | Descriptor: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, PROTEIN (BETA-LACTAMASE), SULFATE ION | Authors: | Maveyraud, L, Mourey, L, Pedelacq, J.D, Guillet, V, Kotra, L.K, Mobashery, S, Samama, J.P. | Deposit date: | 1998-09-02 | Release date: | 1999-09-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis for Clinical Longevity of Carbapenem Antibiotics in the Face of Challenge by the Common Class A Beta-Lactamases from Antibiotic-Resistant Bacteria J.Am.Chem.Soc., 120, 1998
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1BUE
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![BU of 1bue by Molmil](/molmil-images/mine/1bue) | NMC-A CARBAPENEMASE FROM ENTEROBACTER CLOACAE | Descriptor: | PROTEIN (IMIPENEM-HYDROLYSING BETA-LACTAMASE) | Authors: | Swaren, P, Maveyraud, L, Cabantous, S, Pedelacq, J.D, Mourey, L, Frere, J.M, Samama, J.P. | Deposit date: | 1998-09-03 | Release date: | 1999-09-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | X-ray analysis of the NMC-A beta-lactamase at 1.64-A resolution, a class A carbapenemase with broad substrate specificity. J.Biol.Chem., 273, 1998
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3TZZ
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![BU of 3tzz by Molmil](/molmil-images/mine/3tzz) | Crystal structure of a fragment containing the acyltransferase domain of Pks13 from Mycobacterium tuberculosis in the carboxypalmitoylated form at 2.5 A | Descriptor: | 12-mer peptide, 2-(2-METHOXYETHOXY)ETHANOL, GLYCEROL, ... | Authors: | Bergeret, F, Pedelacq, J.D, Mourey, L, Bon, C. | Deposit date: | 2011-09-28 | Release date: | 2012-08-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13 J.Biol.Chem., 287, 2012
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3TZW
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![BU of 3tzw by Molmil](/molmil-images/mine/3tzw) | Crystal structure of a fragment containing the acyltransferase domain of Pks13 from Mycobacterium tuberculosis in the orthorhombic apoform at 2.6 A | Descriptor: | 1,2-ETHANEDIOL, 12-mer peptide, Polyketide synthase PKS13, ... | Authors: | Bergeret, F, Pedelacq, J.D, Mourey, L, Bon, C. | Deposit date: | 2011-09-28 | Release date: | 2012-08-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13 J.Biol.Chem., 287, 2012
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