6SGE
Crystal structure of Human RHOB-GTP in complex with nanobody B6
Summary for 6SGE
| Entry DOI | 10.2210/pdb6sge/pdb |
| Descriptor | Rho-related GTP-binding protein RhoB, Nanobody B6, GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
| Functional Keywords | gtpase, rho, antibody, complex, immune system |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 72181.78 |
| Authors | Soulie, S.,Gence, R.,Cabantous, S.,Lajoie-Mazenc, I.,Favre, G.,Pedelacq, J.D. (deposition date: 2019-08-04, release date: 2019-09-25, Last modification date: 2024-01-24) |
| Primary citation | Bery, N.,Keller, L.,Soulie, M.,Gence, R.,Iscache, A.L.,Cherier, J.,Cabantous, S.,Sordet, O.,Lajoie-Mazenc, I.,Pedelacq, J.D.,Favre, G.,Olichon, A. A Targeted Protein Degradation Cell-Based Screening for Nanobodies Selective toward the Cellular RHOB GTP-Bound Conformation. Cell Chem Biol, 26:1544-, 2019 Cited by PubMed: 31522999DOI: 10.1016/j.chembiol.2019.08.009 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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