5NJI
Structure of the dehydratase domain of PpsC from Mycobacterium tuberculosis in complex with C12:1-CoA
Replaces: 5CF7Summary for 5NJI
Entry DOI | 10.2210/pdb5nji/pdb |
Related | 4ooc 5i0k 5l84 |
Descriptor | Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsC, ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (~{E})-dodec-2-enethioate (3 entities in total) |
Functional Keywords | dehydratase, polyketide, complex, tuberculosis, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 35259.16 |
Authors | Gavalda, S.,Faille, A.,Mourey, L.,Pedelacq, J.D. (deposition date: 2017-03-28, release date: 2017-05-31, Last modification date: 2024-01-17) |
Primary citation | Faille, A.,Gavalda, S.,Slama, N.,Lherbet, C.,Maveyraud, L.,Guillet, V.,Laval, F.,Quemard, A.,Mourey, L.,Pedelacq, J.D. Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases. J. Mol. Biol., 429:1554-1569, 2017 Cited by PubMed: 28377293DOI: 10.1016/j.jmb.2017.03.026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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