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PDB: 488 件
1HWV
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MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY
分子名称: (1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL, 5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'
著者Patel, D.J, Lin, C.H, Geacintov, N.E, Broyde, S, Huang, X, Kolbanovskii, A, Hingerty, B.E, Amin, S.
登録日2001-01-10
公開日2001-03-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
J.Mol.Biol., 306, 2001
1HX4
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MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY
分子名称: (1R)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL, 5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'
著者Patel, D.J, Lin, C.H, Geacintov, N.E, Broyde, S, Huang, X, Kolbanovskii, A, Hingerty, B.E, Amin, S.
登録日2001-01-11
公開日2001-03-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
J.Mol.Biol., 306, 2001
139D
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BU of 139d by Molmil
SOLUTION STRUCTURE OF A PARALLEL-STRANDED G-QUADRUPLEX DNA
分子名称: DNA (5'-D(*TP*TP*GP*GP*GP*GP*T)-3')
著者Patel, D.J, Wang, Y.
登録日1993-09-28
公開日1994-01-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a parallel-stranded G-quadruplex DNA.
J.Mol.Biol., 234, 1993
134D
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BU of 134d by Molmil
SOLUTION STRUCTURE OF A PURINE(DOT)PURINE(DOT)PYRIMIDINE DNA TRIPLEX CONTAINING G(DOT)GC AND T(DOT)AT TRIPLES
分子名称: DNA TRIPLEX
著者Patel, D.J, Radhakrishnan, I.
登録日1993-08-30
公開日1994-04-30
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Solution structure of a purine.purine.pyrimidine DNA triplex containing G.GC and T.AT triples.
Structure, 1, 1993
4IUR
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BU of 4iur by Molmil
crystal structure of SHH1 SAWADEE domain in complex with H3K9me3 peptide
分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ...
著者Patel, D.J, Du, J.
登録日2013-01-21
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
3VRS
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BU of 3vrs by Molmil
Crystal structure of fluoride riboswitch, soaked in Mn2+
分子名称: FLUORIDE ION, Fluoride riboswitch, MANGANESE (II) ION, ...
著者Ren, A.M, Rajashankar, K.R, Patel, D.J.
登録日2012-04-13
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
7DMQ
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BU of 7dmq by Molmil
Cryo-EM structure of LshCas13a-crRNA-anti-tag RNA complex
分子名称: Anti-tag target RNA, CRISPR RNA, CRISPR/Cas system Cas13a
著者Wang, B, Zhang, T, Ding, J, Patel, D.J, Yang, H.
登録日2020-12-05
公開日2021-02-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems.
Mol.Cell, 81, 2021
1EEG
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BU of 1eeg by Molmil
A(GGGG)A HEXAD PAIRING ALIGMENT FOR THE D(G-G-A-G-G-A-G) SEQUENCE
分子名称: DNA (5'-D(*GP*GP*AP*GP*GP*A)-3')
著者Kettani, A, Gorin, A, Majumdar, A, Hermann, T, Skripkin, E, Zhao, H, Jones, R, Patel, D.J.
登録日2000-01-31
公開日2000-04-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations.
J.Mol.Biol., 297, 2000
6EDC
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BU of 6edc by Molmil
hcGAS-16bp dsDNA complex
分子名称: Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*CP*GP*GP*CP*AP*AP*T)-3'), ...
著者Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J.
登録日2018-08-09
公開日2019-05-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.712 Å)
主引用文献Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
3D1D
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BU of 3d1d by Molmil
Hexagonal crystal structure of Tas3 C-terminal alpha motif
分子名称: RNA-induced transcriptional silencing complex protein tas3
著者Li, H, Patel, D.J.
登録日2008-05-05
公開日2009-04-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3D1B
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BU of 3d1b by Molmil
Tetragonal crystal structure of Tas3 C-terminal alpha motif
分子名称: RNA-induced transcriptional silencing complex protein tas3
著者Li, H, Patel, D.J.
登録日2008-05-05
公開日2009-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
2H6Q
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BU of 2h6q by Molmil
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me3 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-06-01
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2GKU
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BU of 2gku by Molmil
Monomeric human telomere DNA tetraplex with 3+1 strand fold topology, two edgewise loops and double-chain reversal loop, NMR, 12 structures
分子名称: Human telomere DNA
著者Luu, K.N, Phan, A.T, Kuryavyi, V.V, Lacroix, L, Patel, D.J.
登録日2006-04-03
公開日2006-08-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the human telomere in k(+) solution: an intramolecular (3 + 1) g-quadruplex scaffold.
J.Am.Chem.Soc., 128, 2006
4FT2
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BU of 4ft2 by Molmil
crystal structure of Zea mays ZMET2 in complex H3(1-15)K9me2 peptide and SAH
分子名称: DNA (cytosine-5)-methyltransferase 1, H3 peptide, S-ADENOSYL-L-HOMOCYSTEINE
著者Du, J, Patel, D.J.
登録日2012-06-27
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants.
Cell(Cambridge,Mass.), 151, 2012
4H9R
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BU of 4h9r by Molmil
Complex structure 5 of DAXX(E225A)/H3.3(sub5,G90A)/H4
分子名称: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
著者Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J.
登録日2012-09-24
公開日2012-10-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.197 Å)
主引用文献DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
7SDE
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BU of 7sde by Molmil
Cryo-EM structure of Nse5/6 heterodimer
分子名称: Non-structural maintenance of chromosome element 5, Ubiquitin-like protein SMT3,DNA repair protein KRE29 chimera
著者Yu, Y, Patel, D.J, Zhao, X.L.
登録日2021-09-29
公開日2021-10-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The cryo-EM structure of Nse5/6 complex with the C terminal part of Nse5
To Be Published
7SJR
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BU of 7sjr by Molmil
Cryo-EM structure of AdnA-AdnB(W325A) in complex with DNA and AMPPNP
分子名称: DNA (70-MER), DNA helicase, IRON/SULFUR CLUSTER, ...
著者Wang, J, Warren, G.M, Shuman, S, Patel, D.J.
登録日2021-10-18
公開日2021-12-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure-activity relationships at a nucleobase-stacking tryptophan required for chemomechanical coupling in the DNA resecting motor-nuclease AdnAB.
Nucleic Acids Res., 50, 2022
7SHP
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BU of 7shp by Molmil
Crystal structure of hSTING in complex with c[2',3'-(ribo-2'-G, xylo-3'-A)-MP](RJ244)
分子名称: (2S,5R,7R,8R,10S,12aR,14R,15R,15aR,16R)-7-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-2,10,15,16-tetrahydroxyoctahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein
著者Xie, W, Lama, L, Yang, X.J, Kuryavyi, V, Nudelman, I, Glickman, J.F, Jones, R.A, Tuschl, T, Patel, D.J.
登録日2021-10-11
公開日2022-10-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Arabinose- and xylose-modified analogs of 2',3'-cGAMP act as STING agonists.
Cell Chem Biol, 2023
7SHO
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Crystal structure of hSTING in complex with c[2',3'-(ara-2'-G, ribo-3'-A)-MP] (RJ242)
分子名称: (2R,5R,7R,8S,10R,12aR,14R,15R,15aS,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-2,10,15,16-tetrahydroxyoctahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein
著者Xie, W, Lama, L, Yang, X.J, Kuryavyi, V, Nudelman, I, Glickman, J.F, Jones, R.A, Tuschl, T, Patel, D.J.
登録日2021-10-10
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Arabinose- and xylose-modified analogs of 2',3'-cGAMP act as STING agonists.
Cell Chem Biol, 2023
6IEJ
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BU of 6iej by Molmil
The C2 domain of cytosolic phospholipase A2 alpha bound to phosphatidylcholine
分子名称: 1,2-dihexanoyl-sn-glycero-3-phosphocholine, CALCIUM ION, Cytosolic phospholipase A2, ...
著者Hirano, Y, Gao, Y.G, Stephenson, D.J, Vu, N.T, Malinina, L, Chalfant, C.E, Patel, D.J, Brown, R.E.
登録日2018-09-14
公開日2019-05-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.206 Å)
主引用文献Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase A2alpha.
Elife, 8, 2019
7VKJ
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Structure of ESRP1 qRRM3 domain
分子名称: Epithelial splicing regulatory protein 1
著者Wu, B.X, Patel, D.J.
登録日2021-09-30
公開日2022-10-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of ESRP1 qRRM3 domain
To Be Published
7WRN
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BU of 7wrn by Molmil
ESRP1 RNaseH-qRRM1 tandem domain
分子名称: Epithelial splicing regulatory protein 1, GLYCEROL
著者Wu, B.X, Guo, W.T, Patel, D.J.
登録日2022-01-27
公開日2023-02-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献ESRP1 RNaseH-qRRM1 tandem domain
To Be Published
2RHU
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BU of 2rhu by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 bound to dimethyl-lysine and in chimera with histone H3.3(28-34)
分子名称: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein, N-DIMETHYL-LYSINE, ...
著者Li, H, Patel, D.J.
登録日2007-10-09
公開日2007-12-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2RI7
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BU of 2ri7 by Molmil
Crystal structure of PHD finger-linker-bromodomain Y17E mutant from human BPTF in the H3(1-9)K4ME2 bound state
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Nucleosome-remodeling factor subunit BPTF, ...
著者Li, H, Patel, D.J.
登録日2007-10-10
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2RI5
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BU of 2ri5 by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 with N358A point mutation
分子名称: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein, TRIETHYLENE GLYCOL
著者Li, H, Patel, D.J.
登録日2007-10-10
公開日2007-12-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007

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