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PDB: 40 件

8H2G
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BU of 8h2g by Molmil
Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2022-10-06
公開日2023-10-11
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structural basis for hydroxy-carboxylic acid receptor 2 activation and allosteric mechanism
To Be Published
7FCI
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BU of 7fci by Molmil
human NTCP in complex with YN69083 Fab
分子名称: Fab Heavy chain, Fab Light chain, Sodium/bile acid cotransporter
著者Park, J.H, Iwamoto, M, Yun, J.H, Uchikubo-Kamo, T, Son, D, Jin, Z, Yoshida, H, Ohki, M, Ishimoto, N, Mizutani, K, Oshima, M, Muramatsu, M, Wakita, T, Shirouzu, M, Liu, K, Uemura, T, Nomura, N, Iwata, S, Watashi, K, Tame, J.R.H, Nishizawa, T, Lee, W, Park, S.Y.
登録日2021-07-14
公開日2022-05-25
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the HBV receptor and bile acid transporter NTCP.
Nature, 606, 2022
6AHG
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BU of 6ahg by Molmil
Trimeric structure of concanavalin A from Canavalia ensiformis
分子名称: CADMIUM ION, CALCIUM ION, Concanavalin-A,Concanavalin-A
著者Park, J.H, Kim, D.S, Park, Y.R, Lee, S.J.
登録日2018-08-18
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Cadmium-substituted concanavalin A and its trimeric complexation
J. Microbiol. Biotechnol., 28(12), 2018
6JCG
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BU of 6jcg by Molmil
Room temperature structure of HIV-1 Integrase catalytic core domain by serial femtosecond crystallography.
分子名称: CACODYLATE ION, Integrase
著者Park, J.H, Shi, Y, Han, J, Li, X, Kim, T.H, Yun, J.H.
登録日2019-01-28
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers.
Int J Mol Sci, 20, 2019
6JCF
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BU of 6jcf by Molmil
Cryogenic structure of HIV-1 Integrase catalytic core domain by synchrotron
分子名称: CACODYLATE ION, Integrase
著者Park, J.H, Han, J, Kim, T.H, Yun, J.H, Lee, W.
登録日2019-01-28
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers.
Int J Mol Sci, 20, 2019
4J4Q
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BU of 4j4q by Molmil
Crystal structure of active conformation of GPCR opsin stabilized by octylglucoside
分子名称: ACETATE ION, Guanine nucleotide-binding protein G(t) subunit alpha-1, PALMITIC ACID, ...
著者Park, J.H, Morizumi, T, Li, Y, Hong, J.E, Pai, E.F, Hofmann, K.P, Choe, H.W, Ernst, O.P.
登録日2013-02-07
公開日2013-10-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Opsin, a structural model for olfactory receptors?
Angew.Chem.Int.Ed.Engl., 52, 2013
4HJO
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BU of 4hjo by Molmil
Crystal structure of the inactive EGFR tyrosine kinase domain with erlotinib
分子名称: Epidermal growth factor receptor, [6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE
著者Park, J.H, Lemmon, M.A.
登録日2012-10-13
公開日2012-11-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain.
Biochem.J., 448, 2012
8K5C
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BU of 8k5c by Molmil
Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
分子名称: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Human hydroxycarboxylic acid receptor 2
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-07-21
公開日2023-11-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5B
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BU of 8k5b by Molmil
Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
分子名称: Human Hydroxycarboxylic acid receptor 2, NICOTINIC ACID
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-07-21
公開日2023-11-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5D
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BU of 8k5d by Molmil
Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
分子名称: 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Human hydroxycarboxylic acid receptor 2
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-07-21
公開日2023-11-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8I7W
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BU of 8i7w by Molmil
Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
分子名称: 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-02-02
公開日2024-02-07
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8I7V
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BU of 8i7v by Molmil
Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
分子名称: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-02-02
公開日2024-02-07
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
5JEB
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BU of 5jeb by Molmil
Crystal structure of EGFR tyrosine kinase domain with novel inhibitor of active state of HER2
分子名称: 3-(furan-2-yl)-N-[5-(furan-2-yl)-2-methoxyphenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Epidermal growth factor receptor, SULFATE ION
著者Park, J.H, Lemmon, M.A.
登録日2016-04-18
公開日2016-09-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.298 Å)
主引用文献Overcoming resistance to HER2 inhibitors through state-specific kinase binding.
Nat.Chem.Biol., 12, 2016
5D43
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BU of 5d43 by Molmil
crystal structrue of Mouse centrin 1 in calcium-saturated form
分子名称: CALCIUM ION, Centrin-1
著者Park, J.H, Kim, S.Y, Kim, D.S.
登録日2015-08-07
公開日2016-09-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Crystal Structure of Wild-Type Centrin 1 from Mus musculus Occupied by Ca2.
Biochemistry Mosc., 82, 2017
5YGM
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BU of 5ygm by Molmil
Monomeric structure of concanavalin A at pH 7.5 from Carnivalia ensiformis
分子名称: CALCIUM ION, Concanavalin-A, MANGANESE (II) ION
著者Park, J.H, Park, Y.R, Lee, S.J.
登録日2017-09-24
公開日2017-10-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Heterometal-Coordinated Monomeric Concanavalin A at pH 7.5 from Canavalia ensiformis
J. Microbiol. Biotechnol., 27, 2017
3CAP
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BU of 3cap by Molmil
Crystal Structure of Native Opsin: the G Protein-Coupled Receptor Rhodopsin in its Ligand-free State
分子名称: 2-O-octyl-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ...
著者Park, J.H, Scheerer, P, Hofmann, K.P, Choe, H.-W, Ernst, O.P.
登録日2008-02-20
公開日2008-06-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the ligand-free G-protein-coupled receptor opsin
Nature, 454, 2008
6KY2
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BU of 6ky2 by Molmil
Crystal Structure of Arginine Kinase wild type from Daphnia magna
分子名称: Arginine kinase, PHOSPHATE ION
著者Park, J.H, Rao, Z, Kim, S.Y, Kim, D.S.
登録日2019-09-16
公開日2020-09-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Insight into Structural Aspects of Histidine 284 of Daphnia magna Arginine Kinase.
Mol.Cells, 43, 2020
6L2U
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BU of 6l2u by Molmil
Soluble methane monooxygenase reductase FAD-binding domain from Methylosinus sporium.
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Methane monooxygenase
著者Park, J.H, Ha, S.C, Rao, Z, Yoo, H, Yoon, C, Kim, S.Y, Kim, D.S, Lee, S.J.
登録日2019-10-07
公開日2021-03-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Elucidation of the electron transfer environment in the MMOR FAD-binding domain from Methylosinus sporium 5.
Dalton Trans, 50, 2021
8HNJ
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BU of 8hnj by Molmil
Domain-stabilized glutamine-binding protein
分子名称: GLUTAMINE, Glutamine ABC transporter, periplasmic glutamine-binding protein GlnH
著者Choi, S.H, Park, J.H, Seo, M.H, Park, K.W, Lee, W.K.
登録日2022-12-08
公開日2023-07-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Domain-wise dissection of thermal stability enhancement in multidomain proteins.
Int.J.Biol.Macromol., 237, 2023
5ZTK
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BU of 5ztk by Molmil
Synchrotron structure of light-driven chloride pump having an NTQ motif
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Park, J.H, Park, S.Y, Lee, W.
登録日2018-05-04
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency
J. Biol. Chem., 294, 2019
3OX4
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BU of 3ox4 by Molmil
Structures of iron-dependent alcohol dehydrogenase 2 from Zymomonas mobilis ZM4 complexed with NAD cofactor
分子名称: Alcohol dehydrogenase 2, FE (II) ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Moon, J.H, Lee, H.J, Song, J.M, Park, S.Y, Park, M.Y, Park, H.M, Sun, J, Park, J.H, Kim, J.S.
登録日2010-09-21
公開日2011-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of iron-dependent alcohol dehydrogenase 2 from Zymomonas mobilis ZM4 with and without NAD+ cofactor
J.Mol.Biol., 407, 2011
3OWO
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BU of 3owo by Molmil
Structures of iron-dependent alcohol dehydrogenase 2 from Zymomonas mobilis ZM4 with and without NAD cofactor
分子名称: Alcohol dehydrogenase 2, FE (II) ION
著者Moon, J.H, Lee, H.J, Song, J.M, Park, S.Y, Park, M.Y, Park, H.M, Sun, J, Park, J.H, Kim, J.S.
登録日2010-09-20
公開日2011-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structures of iron-dependent alcohol dehydrogenase 2 from Zymomonas mobilis ZM4 with and without NAD+ cofactor
J.Mol.Biol., 407, 2011
6K6I
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BU of 6k6i by Molmil
The crystal structure of light-driven cyanobacterial chloride importer from Mastigocladopsis repens
分子名称: CHLORIDE ION, Cyanobacterial chloride importer, OLEIC ACID, ...
著者Yun, J.H, Park, J.H, Jin, Z, Ohki, M, Wang, Y, Lupala, C.S, Kim, M, Liu, H, Park, S.Y, Lee, W.
登録日2019-06-03
公開日2020-06-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of light-driven cyanobacterial chloride importer from Mastigocladopsis repens
To Be Published
6K6K
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The crystal structure of light-driven cyanobacterial chloride importer (N63A/P118A) Mastigocladopsis repens
分子名称: CHLORIDE ION, Cyanobacterial chloride importer, OLEIC ACID, ...
著者Yun, J.H, Park, J.H, Jin, Z, Ohki, M, Wang, Y, Lupala, C.S, Kim, M, Liu, H, Park, S.Y, Lee, W.
登録日2019-06-03
公開日2020-06-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.197 Å)
主引用文献The crystal structure of light-driven cyanobacterial chloride importer (N63A/P118A) Mastigocladopsis repens
To Be Published
6K6J
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The crystal structure of light-driven cyanobacterial chloride importer from Mastigocladopsis repens with Bromide ion
分子名称: BROMIDE ION, Cyanobacterial chloride importer, OLEIC ACID, ...
著者Yun, J.H, Park, J.H, Jin, Z, Ohki, M, Wang, Y, Lupala, C.S, Kim, M, Liu, H, Park, S.Y, Lee, W.
登録日2019-06-03
公開日2020-06-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of light-driven cyanobacterial chloride importer from Mastigocladopsis repens with Bromide ion
To Be Published

 

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