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PDB: 414 results

3V6R
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BU of 3v6r by Molmil
Discovery of potent and selective covalent inhibitors of JNK
Descriptor: 4-{[4-(dimethylamino)butanoyl]amino}-N-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10
Authors:Park, H, LoGrasso, P.V, Laughlin, J.D.
Deposit date:2011-12-20
Release date:2012-02-01
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of potent and selective covalent inhibitors of JNK.
Chem.Biol., 19, 2012
3V6S
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BU of 3v6s by Molmil
Discovery of potent and selective covalent inhibitors of JNK
Descriptor: 3-{[4-(dimethylamino)butanoyl]amino}-N-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10
Authors:Park, H, Laughlin, J.D, LoGrasso, P.V.
Deposit date:2011-12-20
Release date:2012-02-01
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Discovery of potent and selective covalent inhibitors of JNK.
Chem.Biol., 19, 2012
5GLG
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BU of 5glg by Molmil
The novel function of Osm1 under anaerobic condition in the ER was revealed by crystal structure of Osm1, a soluble fumarate reductase in yeast
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Fumarate reductase 2, SUCCINIC ACID
Authors:Park, H.H, Choi, J.Y.
Deposit date:2016-07-11
Release date:2017-07-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular basis of maintaining an oxidizing environment under anaerobiosis by soluble fumarate reductase.
Nat Commun, 9, 2018
3QF2
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BU of 3qf2 by Molmil
Crystal structure of NALP3 PYD
Descriptor: NACHT, LRR and PYD domains-containing protein 3
Authors:Park, H.H, Bae, J.Y.
Deposit date:2011-01-21
Release date:2011-08-31
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly
J.Biol.Chem., 286, 2011
3RF3
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BU of 3rf3 by Molmil
Shigella IpaA-VBS3 in complex with human vinculin
Descriptor: CACODYLATE ION, Invasin ipaA, Vinculin
Authors:Park, H, Sharff, A, Izard, T.
Deposit date:2011-04-05
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Novel vinculin binding site of the IpaA invasin of Shigella.
J.Biol.Chem., 286, 2011
7XHZ
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BU of 7xhz by Molmil
Crystal structure of SAV2152 from MRSA
Descriptor: Phosphatase, SAV2152
Authors:Park, H.J, Seok, S.H, Kim, J.H.
Deposit date:2022-04-11
Release date:2023-04-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of SAV2152 from MRSA
To Be Published
3TJ5
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BU of 3tj5 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii
Descriptor: Antigenic heat-stable 120 kDa protein, GLYCEROL, Vinculin
Authors:Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
Deposit date:2011-08-23
Release date:2011-09-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
6N2U
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BU of 6n2u by Molmil
IL-8 Structure from Bacterial Expression Source
Descriptor: Interleukin-8
Authors:Park, H, Jung, J.H, Luo, J.L.
Deposit date:2018-11-14
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.254 Å)
Cite:IL-8 Structure from Bacterial Expression Source
To Be Published
3TJ6
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BU of 3tj6 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii
Descriptor: Antigenic heat-stable 120 kDa protein, Vinculin
Authors:Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
Deposit date:2011-08-23
Release date:2011-09-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
7BR9
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BU of 7br9 by Molmil
Crystal structure of mus musculus IRG1
Descriptor: Cis-aconitate decarboxylase
Authors:Park, H.H, Chun, H.L.
Deposit date:2020-03-27
Release date:2021-02-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of mouse IRG1 suggests that cis-aconitate decarboxylase has an open and closed conformation.
Plos One, 15, 2020
7D1I
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BU of 7d1i by Molmil
Crystal structure of acinetobacter baumannii MurG
Descriptor: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Authors:Park, H.H, Jeong, k.H.
Deposit date:2020-09-14
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.487 Å)
Cite:Putative hexameric glycosyltransferase functional unit revealed by the crystal structure of Acinetobacter baumannii MurG
Iucrj, 8, 2021
7D27
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BU of 7d27 by Molmil
Structure of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase
Descriptor: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
Authors:Park, H.H, Jeong, K.H.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Wide-open conformation of UDP-MurNc-tripeptide ligase revealed by the substrate-free structure of MurE from Acinetobacter baumannii.
Febs Lett., 595, 2021
7BRA
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BU of 7bra by Molmil
Bacillus subtilis IRG1
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Bacillus subtilis IRG1, SULFATE ION
Authors:Park, H.H, Chun, H.L.
Deposit date:2020-03-27
Release date:2021-02-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.785 Å)
Cite:Enzymatic reaction mechanism of cis-aconitate decarboxylase based on the crystal structure of IRG1 from Bacillus subtilis.
Sci Rep, 10, 2020
1T4I
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BU of 1t4i by Molmil
Crystal Structure of a DNA Decamer Containing a Thymine-dimer
Descriptor: 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3'
Authors:Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.S, Kang, C.
Deposit date:2004-04-29
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of a DNA Decamer Containing a cis-syn Thymine-dimer
Proc.Natl.Acad.Sci.USA, 99, 2002
7BSO
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BU of 7bso by Molmil
Crystal structure of the human NLRP9 pyrin domain
Descriptor: NACHT, LRR and PYD domains-containing protein 9
Authors:Park, H.H, Ha, H.J.
Deposit date:2020-03-31
Release date:2021-02-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structure of the human NLRP9 pyrin domain reveals a bent N-terminal loop that may regulate inflammasome assembly.
Febs Lett., 594, 2020
7E52
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BU of 7e52 by Molmil
Acinetobacter baumannii Thioredoxin reductase
Descriptor: Thioredoxin reductase
Authors:Park, H.H, Chun, H.L.
Deposit date:2021-02-16
Release date:2022-02-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Acinetobacter baumannii Thioredoxin reductase
To Be Published
5XPC
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BU of 5xpc by Molmil
Crystal Structure of Drep4 CIDE domain
Descriptor: DNAation factor-related protein 4, GLYCEROL
Authors:Park, H.H, Jeong, J.H.
Deposit date:2017-06-01
Release date:2017-07-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:CIDE domains form functionally important higher-order assemblies for DNA fragmentation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5XPB
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BU of 5xpb by Molmil
Crystal Structure of Selenomethionine labelled Drep4 CIDE domain
Descriptor: DNAation factor-related protein 4
Authors:Park, H.H, Jeong, J.H.
Deposit date:2017-06-01
Release date:2018-06-20
Method:X-RAY DIFFRACTION (2.996 Å)
Cite:Crystal Structure of Selenomethionine labelled Drep4 CIDE domain
To Be Published
5YC1
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BU of 5yc1 by Molmil
TRAF4_GPIb complex
Descriptor: GPIb peptide, TNF receptor-associated factor 4
Authors:Park, H.H, Kim, C.M.
Deposit date:2017-09-06
Release date:2017-10-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Molecular basis for unique specificity of human TRAF4 for platelets GPIb beta and GPVI
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W3D
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BU of 5w3d by Molmil
The structure of kinesin-14 wild-type Ncd-ADP dimer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein claret segregational
Authors:Park, H.W, Ma, Z, Chacko, J, Jiang, S.M, Robinson, R.C, Endow, S.A.
Deposit date:2017-06-07
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
Sci Rep, 7, 2017
2MCY
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BU of 2mcy by Molmil
CR1 Sushi domains 2 and 3
Descriptor: Complement receptor type 1
Authors:Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P.
Deposit date:2013-08-27
Release date:2013-11-13
Last modified:2014-01-22
Method:SOLUTION NMR
Cite:Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
2MCZ
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BU of 2mcz by Molmil
CR1 Sushi domains 1 and 2
Descriptor: Complement receptor type 1
Authors:Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P.
Deposit date:2013-08-27
Release date:2013-11-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
2OF5
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BU of 2of5 by Molmil
Oligomeric Death Domain complex
Descriptor: Death domain-containing protein CRADD, Leucine-rich repeat and death domain-containing protein
Authors:Park, H.H, Logette, E, Raunser, S, Cuenin, S, Walz, T, Tschopp, J, Wu, H.
Deposit date:2007-01-02
Release date:2007-04-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex.
Cell(Cambridge,Mass.), 128, 2007
8HJJ
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BU of 8hjj by Molmil
Anti-CRISPR protein AcrIC9
Descriptor: Anti-CRISPR protein Type I-C9
Authors:Kang, Y.J, Park, H.H.
Deposit date:2022-11-23
Release date:2023-09-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of AcrIC9 revealing the putative inhibitory mechanism of AcrIC9 against the type IC CRISPR-Cas system.
Iucrj, 10, 2023
3CPF
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BU of 3cpf by Molmil
Crystal structure of human eukaryotic translation initiation factor EIF5A
Descriptor: Eukaryotic translation initiation factor 5A-1, UNKNOWN ATOM OR ION
Authors:Nedyalkova, L, Tong, Y, Tempel, W, Hong, B, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-03-31
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human eIF5A1: insight into functional similarity of human eIF5A1 and eIF5A2.
Proteins, 75, 2009

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