3CPF

Crystal structure of human eukaryotic translation initiation factor EIF5A

Summary for 3CPF

Entry DOI	10.2210/pdb3cpf/pdb
Descriptor	Eukaryotic translation initiation factor 5A-1, UNKNOWN ATOM OR ION (3 entities in total)
Functional Keywords	structural genomics consortium, leukemia, apoptosis, sgc, hypusine, initiation factor, nucleus, protein biosynthesis, cell cycle
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P63241
Total number of polymer chains	2
Total formula weight	30340.85
Authors	Nedyalkova, L.,Tong, Y.,Tempel, W.,Hong, B.,MacKenzie, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2008-03-31, release date: 2008-04-15, Last modification date: 2024-11-20)
Primary citation	Tong, Y.,Park, I.,Hong, B.S.,Nedyalkova, L.,Tempel, W.,Park, H.W. Crystal structure of human eIF5A1: insight into functional similarity of human eIF5A1 and eIF5A2. Proteins, 75:1040-1045, 2009 Cited by PubMed: 19280598 DOI: 10.1002/prot.22378 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation