3RIX
 
 | | 1.7A resolution structure of a firefly luciferase-Aspulvinone J inhibitor complex | | 分子名称: | (5Z)-4-hydroxy-3-[(2R)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]-5-{[(2R)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methylidene}furan-2(5H)-one, Luciferin 4-monooxygenase | | 著者 | Lovell, S, Battaile, K.P, Lopez, P.C, Auld, D.S, Schultz, P.J, MacArthur, R, Shen, M, Tamayo, G, Inglese, J, Sherman, D.H. | | 登録日 | 2011-04-14 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors.
Chem.Biol., 18, 2011
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3S3Y
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3RUN
 | | New strategy to analyze structures of glycopeptide antibiotic-target complexes | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Economou, N.J, Townsend, T.M, Loll, P.J. | | 登録日 | 2011-05-05 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A carrier protein strategy yields the structure of dalbavancin.
J.Am.Chem.Soc., 134, 2012
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3SI7
 | | The crystal structure of the NBD1 domain of the mouse CFTR protein, deltaF508 mutant | | 分子名称: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... | | 著者 | Brautigam, C.A, Caspa, E, Thomas, P.J. | | 登録日 | 2011-06-17 | | 公開日 | 2012-02-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Requirements for efficient correction of DeltaF508 CFTR revealed by analyses of evolved sequences
Cell(Cambridge,Mass.), 148, 2012
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3SMR
 | | Crystal structure of human WD repeat domain 5 with compound | | 分子名称: | 1,2-ETHANEDIOL, 2-chloro-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide, UNKNOWN ATOM OR ION, ... | | 著者 | Dong, A, Dombrovski, L, Wasney, G.A, Tempel, W, Senisterra, G, Bolshan, Y, Smil, D, Nguyen, K.T, Hajian, T, Poda, G, Al-Awar, R, Bountra, C, Weigelt, J, Edwards, A.M, Brown, P.J, Schapira, M, Arrowsmith, C.H, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2011-06-28 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
Biochem. J., 449, 2013
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3SMQ
 | | Crystal structure of protein arginine methyltransferase 3 | | 分子名称: | 1-(1,2,3-benzothiadiazol-6-yl)-3-[2-(cyclohex-1-en-1-yl)ethyl]urea, CHLORIDE ION, Protein arginine N-methyltransferase 3, ... | | 著者 | Dobrovetsky, E, Dong, A, Walker, J.R, Siarheyeva, A, Senisterra, G, Wasney, G.A, Smil, D, Bolshan, Y, Nguyen, K.T, Allali-Hassani, A, Hajian, T, Poda, G, Bountra, C, Weigelt, J, Edwards, A.M, Al-Awar, R, Brown, P.J, Schapira, M, Arrowsmith, C.H, Vedadi, M, Structural Genomics Consortium (SGC) | | 登録日 | 2011-06-28 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An allosteric inhibitor of protein arginine methyltransferase 3.
Structure, 20, 2012
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3S2Z
 | | Crystal structure of the Lactobacillus johnsonii cinnamoyl esterase LJ0536 S106A mutant in complex with caffeic acid | | 分子名称: | CAFFEIC ACID, CHLORIDE ION, Cinnamoyl esterase | | 著者 | Stogios, P.J, Lai, K.K, Vu, C, Xu, X, Cui, H, Molloy, S, Gonzalez, C.F, Yakunin, A, Savchenko, A. | | 登録日 | 2011-05-17 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | An inserted alpha/beta subdomain shapes the catalytic pocket of Lactobacillus johnsonii cinnamoyl esterase.
Plos One, 6, 2011
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3RUM
 | | New strategy to analyze structures of glycopeptide antibiotic-target complexes | | 分子名称: | 3-amino-2,3,6-trideoxy-alpha-L-ribo-hexopyranose, ISOPROPYL ALCOHOL, Maltose-binding periplasmic protein, ... | | 著者 | Economou, N.J, Weeks, S.D, Grasty, K.C, Nahoum, V, Loll, P.J. | | 登録日 | 2011-05-05 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | | 主引用文献 | A carrier protein strategy yields the structure of dalbavancin.
J.Am.Chem.Soc., 134, 2012
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3S3Z
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3RUL
 | | New strategy to analyze structures of glycopeptide-target complexes | | 分子名称: | 10-METHYLUNDECANOIC ACID, 2-amino-2-deoxy-beta-D-glucopyranuronic acid, CHLORIDE ION, ... | | 著者 | Economou, N.J, Nahoum, V, Weeks, S.D, Grasty, K.C, Loll, P.J. | | 登録日 | 2011-05-05 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A carrier protein strategy yields the structure of dalbavancin.
J.Am.Chem.Soc., 134, 2012
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3S4G
 | | Low Resolution Structure of STNV complexed with RNA | | 分子名称: | Capsid protein, RNA (5'-R(P*AP*AP*A)-3'), RNA (5'-R(P*UP*UP*UP*U)-3') | | 著者 | Lane, S.W, Dennis, C.A, Lane, C.L, Trinh, C.H, Rizkallah, P.J, Stockley, P.G, Phillips, S.E.V. | | 登録日 | 2011-05-19 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (6 Å) | | 主引用文献 | Construction and crystal structure of recombinant STNV capsids.
J.Mol.Biol., 413, 2011
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3SED
 | | Crystal Structure of Ketosteroid Isomerase Variant M105A from Pseudomonos putida | | 分子名称: | Steroid Delta-isomerase | | 著者 | Somarowthu, S, Brodkin, H.R, D'Aquino, J.A, Ringe, D, Ondrechen, M.J, Beuning, P.J. | | 登録日 | 2011-06-10 | | 公開日 | 2011-08-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | | 主引用文献 | A tale of two isomerases: compact versus extended active sites in ketosteroid isomerase and phosphoglucose isomerase.
Biochemistry, 50, 2011
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3SLB
 | | Crystal structure of BA2930 in complex with AcCoA and cytosine | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-AMINOPYRIMIDIN-2(1H)-ONE, ... | | 著者 | Klimecka, M.M, Chruszcz, M, Porebski, P.J, Cymborowski, M, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2011-06-24 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of BA2930 in complex with AcCoA and cytosine
TO BE PUBLISHED
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3SLF
 | | Crystal structure of BA2930 in complex with AcCoA and uracil | | 分子名称: | ACETYL COENZYME *A, Aminoglycoside N3-acetyltransferase, CHLORIDE ION, ... | | 著者 | Klimecka, M.M, Chruszcz, M, Porebski, P.J, Cymborowski, M, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2011-06-24 | | 公開日 | 2011-07-20 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of BA2930 in complex with AcCoA and uracil
TO BE PUBLISHED
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3S0P
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3RPI
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3QXX
 | | Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with GDP and 8-aminocaprylic acid | | 分子名称: | 1,2-ETHANEDIOL, 8-aminooctanoic acid, Dethiobiotin synthetase, ... | | 著者 | Porebski, P.J, Klimecka, M.M, Chruszcz, M, Murzyn, K, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2011-03-02 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members.
Febs J., 279, 2012
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3SX0
 | | Crystal structure of Dot1l in complex with a brominated SAH analog | | 分子名称: | (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)butanoic acid (non-preferred name), Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... | | 著者 | Yu, W, Tempel, W, Smil, D, Schapira, M, Li, Y, Vedadi, M, Nguyen, K.T, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2011-07-14 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Bromo-deaza-SAH: a potent and selective DOT1L inhibitor.
Bioorg. Med. Chem., 21, 2013
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3T7B
 | | Crystal Structure of N-acetyl-L-glutamate kinase from Yersinia pestis | | 分子名称: | Acetylglutamate kinase, GLUTAMIC ACID, S,R MESO-TARTARIC ACID | | 著者 | Demas, M.W, Solberg, R.G, Cooper, D.R, Chruszcz, M, Porebski, P.J, Zheng, H, Onopriyenko, O, Skarina, T, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2011-07-29 | | 公開日 | 2011-09-14 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of N-acetyl-L-glutamate kinase from Yersinia pestis
To be Published
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6CNY
 | | 2.3 Angstrom Structure of Phosphodiesterase treated Vivid (complex with FMN) | | 分子名称: | FLAVIN MONONUCLEOTIDE, Vivid PAS protein VVD | | 著者 | Zoltowski, B.D, Shabalin, I.G, Kowiel, M, Porebski, P.J, Crane, B.R, Bilwes, A.M. | | 登録日 | 2018-03-09 | | 公開日 | 2018-03-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conformational switching in the fungal light sensor Vivid.
Science, 316, 2007
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6CIG
 | | CRYSTAL STRUCTURE ANALYSIS OF SELENOMETHIONINE SUBSTITUTED ISOFLAVONE O-METHYLTRANSFERASE | | 分子名称: | GLYCEROL, Isoflavone-7-O-methyltransferase 8, N-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINOPROPANESULFONIC ACID, ... | | 著者 | Zubieta, C, Dixon, R.A, Shabalin, I.G, Kowiel, M, Porebski, P.J, Noel, J.P. | | 登録日 | 2018-02-23 | | 公開日 | 2018-03-07 | | 最終更新日 | 2022-03-23 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases.
Nat. Struct. Biol., 8, 2001
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3QE5
 | | Complete structure of Streptococcus mutans Antigen I/II carboxy-terminus | | 分子名称: | CALCIUM ION, MAGNESIUM ION, Major cell-surface adhesin PAc, ... | | 著者 | Larson, M.R, Rajashankar, K.R, Crowley, P.J, Kelly, C, Mitchell, T.J, Brady, L.J, Deivanayagam, C. | | 登録日 | 2011-01-19 | | 公開日 | 2011-04-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of the C-terminal Region of Streptococcus mutans Antigen I/II and Characterization of Salivary Agglutinin Adherence Domains.
J.Biol.Chem., 286, 2011
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3RAV
 | | Horse spleen apo-ferritin with bound Pentobarbital | | 分子名称: | 5-ethyl-5-[(2S)-pentan-2-yl]pyrimidine-2,4,6(1H,3H,5H)-trione, CADMIUM ION, Ferritin light chain, ... | | 著者 | Oakley, S.H, Vedula, L.S, Xi, J, Liu, R, Eckenhoff, R.G, Loll, P.J. | | 登録日 | 2011-03-28 | | 公開日 | 2011-05-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | High resolution view of barbiturate recognition by a protein binding site
to be published
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6COA
 | | 1.2 A Structure of Thaumatin Crystallized in Gel | | 分子名称: | L(+)-TARTARIC ACID, Thaumatin-1 | | 著者 | Sauter, C, Lorber, B, Shabalin, I.G, Porebski, P.J, Brzezinski, D, Giege, R. | | 登録日 | 2018-03-12 | | 公開日 | 2018-03-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Towards atomic resolution with crystals grown in gel: the case of thaumatin seen at room temperature.
Proteins, 48, 2002
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3TLU
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-24' oxidized mutant in a locally-closed conformation (LC1 subtype) | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-08-30 | | 公開日 | 2012-05-16 | | 最終更新日 | 2012-06-27 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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