2Y4Z
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![BU of 2y4z by Molmil](/molmil-images/mine/2y4z) | Structure of the amino-terminal capsid restriction escape mutation N- MLV L10W | Descriptor: | CAPSID PROTEIN P30, GLYCEROL | Authors: | Goldstone, D.C, Holden-Dye, K, Ohkura, S, Stoye, J.P, Taylor, I.A. | Deposit date: | 2011-01-11 | Release date: | 2011-11-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Novel Escape Mutants Suggest an Extensive Trim5Alpha Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein. Plos Pathog., 7, 2011
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8SFC
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![BU of 8sfc by Molmil](/molmil-images/mine/8sfc) | Crystal structure of the engineered SsoPox variant IVA4 in alternate state | Descriptor: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION, ... | Authors: | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | Deposit date: | 2023-04-10 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase To Be Published
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8SFK
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![BU of 8sfk by Molmil](/molmil-images/mine/8sfk) | Crystal structure of the engineered SsoPox variant IVE2 | Descriptor: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION, ... | Authors: | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | Deposit date: | 2023-04-11 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase To Be Published
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1WA7
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![BU of 1wa7 by Molmil](/molmil-images/mine/1wa7) | SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND | Descriptor: | HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1), TYROSINE-PROTEIN KINASE LYN | Authors: | Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H. | Deposit date: | 2004-10-25 | Release date: | 2005-07-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck. Biochemistry, 41, 2002
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2XS8
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![BU of 2xs8 by Molmil](/molmil-images/mine/2xs8) | Crystal Structure of ALIX in complex with the SIVagmTan-1 AYDPARKLL Late Domain | Descriptor: | PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN, SIVAGMTAN-1 GAG P6 | Authors: | Zhai, Q, Landesman, M, Robinson, H, Sundquist, W.I, Hill, C.P. | Deposit date: | 2010-09-24 | Release date: | 2010-11-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Identification and Structural Characterization of the Alix-Binding Late Domains of Sivmac239 and Sivagmtan-1. J.Virol., 85, 2011
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2XQB
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![BU of 2xqb by Molmil](/molmil-images/mine/2xqb) | Crystal Structure of anti-IL-15 Antibody in Complex with human IL-15 | Descriptor: | ANTI-IL-15 ANTIBODY, INTERLEUKIN 15, SULFATE ION | Authors: | Lowe, D.C, Gerhardt, S, Ward, A, Hargreaves, D, Anderson, M, StGallay, S, Vousden, K, Ferraro, F, Pauptit, R.A, Cochrane, D, Pattison, D.V, Buchanan, C, Popovic, B, Finch, D.K, Wilkinson, T, Sleeman, M, Vaughan, T.J, Cruwys, S, Mallinder, P.R. | Deposit date: | 2010-09-01 | Release date: | 2010-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Engineering a High Affinity Anti-Il-15 Antibody: Crystal Structure Reveals an Alpha-Helix in Vh Cdr3 as Key Component of Paratope. J.Mol.Biol., 406, 2011
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2XS1
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![BU of 2xs1 by Molmil](/molmil-images/mine/2xs1) | Crystal Structure of ALIX in complex with the SIVmac239 PYKEVTEDL Late Domain | Descriptor: | GAG POLYPROTEIN, PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN | Authors: | Zhai, Q, Landesman, M, Robinson, H, Sundquist, W.I, Hill, C.P. | Deposit date: | 2010-09-24 | Release date: | 2010-11-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.296 Å) | Cite: | Identification and Structural Characterization of the Alix-Binding Late Domains of Sivmac239 and Sivagmtan-1. J.Virol., 85, 2011
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4U2A
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![BU of 4u2a by Molmil](/molmil-images/mine/4u2a) | Structure of a lectin from the seeds of Vatairea macrocarpa complexed with GalNAc | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, CITRIC ACID, ... | Authors: | Sousa, B.L, Silva-Filho, J.C, Kumar, P, Lyskowski, A, Bezerra, G.A, Delatorre, P, Rocha, B.A.M, Nagano, C.S, Gruber, K, Cavada, B.S. | Deposit date: | 2014-07-16 | Release date: | 2014-12-31 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | High-resolution structure of a new Tn antigen-binding lectin from Vatairea macrocarpa and a comparative analysis of Tn-binding legume lectins. Int.J.Biochem.Cell Biol., 59C, 2014
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2Y30
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![BU of 2y30 by Molmil](/molmil-images/mine/2y30) | Simocyclinone D8 bound form of TetR-like repressor SimR | Descriptor: | CHLORIDE ION, PUTATIVE REPRESSOR SIMREG2, SIMOCYCLINONE D8 | Authors: | Le, T.B.K, Stevenson, C.E.M, Fiedler, H.-P, Maxwell, A, Lawson, D.M, Buttner, M.J. | Deposit date: | 2010-12-17 | Release date: | 2011-03-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of the Tetr-Like Simocyclinone Efflux Pump Repressor, Simr, and the Mechanism of Ligand-Mediated Derepression. J.Mol.Biol., 408, 2011
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2Y3P
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![BU of 2y3p by Molmil](/molmil-images/mine/2y3p) | Crystal structure of N-terminal domain of GyrA with the antibiotic simocyclinone D8 | Descriptor: | DNA GYRASE SUBUNIT A, MAGNESIUM ION, SIMOCYCLINONE D8 | Authors: | Edwards, M.J, Flatman, R.H, Mitchenall, L.A, Stevenson, C.E.M, Le, T.B.K, Clarke, T.A, McKay, A.R, Fiedler, H.-P, Buttner, M.J, Lawson, D.M, Maxwell, A. | Deposit date: | 2010-12-22 | Release date: | 2010-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase. Science, 326, 2009
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5VFE
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![BU of 5vfe by Molmil](/molmil-images/mine/5vfe) | Synaptotagmin 1 C2A domain, lead-bound | Descriptor: | LEAD (II) ION, SULFATE ION, Synaptotagmin-1 | Authors: | Taylor, A.B, Hart, P.J, Igumenova, T.I. | Deposit date: | 2017-04-07 | Release date: | 2018-04-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | High affinity interactions of Pb2+with synaptotagmin I. Metallomics, 10, 2018
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4UBK
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![BU of 4ubk by Molmil](/molmil-images/mine/4ubk) | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 7.40 MGy at 100K | Descriptor: | DIETHYL HYDROGEN PHOSPHATE, E3 | Authors: | Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G. | Deposit date: | 2014-08-13 | Release date: | 2015-08-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
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4U3Y
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![BU of 4u3y by Molmil](/molmil-images/mine/4u3y) | |
4U41
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![BU of 4u41 by Molmil](/molmil-images/mine/4u41) | MAP4K4 Bound to inhibitor compound 1 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[(3S)-3-(4-methyl-1H-pyrazol-3-yl)piperidin-1-yl]pyrido[3,2-d]pyrimidin-4-amine, MAGNESIUM ION, ... | Authors: | Harris, S.F, Wu, P, Coons, M. | Deposit date: | 2014-07-23 | Release date: | 2016-01-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Plasticity and Kinase Activation in a Cohort of MAP4K4 Structures to be published
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4U0O
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![BU of 4u0o by Molmil](/molmil-images/mine/4u0o) | Crystal structure of Thermosynechococcus elongatus Lipoyl Synthase 2 complexed with MTA and DTT | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 5'-DEOXY-5'-METHYLTHIOADENOSINE, IRON/SULFUR CLUSTER, ... | Authors: | Harmer, J.E, Hiscox, M.J, Dinis, P.C, Sandy, J, Roach, P.L. | Deposit date: | 2014-07-13 | Release date: | 2014-08-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions. Biochem.J., 464, 2014
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2XUB
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![BU of 2xub by Molmil](/molmil-images/mine/2xub) | Human RPC62 subunit structure | Descriptor: | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 | Authors: | Lefevre, S, Legrand, P, Fribourg, S. | Deposit date: | 2010-10-18 | Release date: | 2011-03-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Function Analysis of Hrpc62 Provides Insights Into RNA Polymerase III Transcription Nat.Struct.Mol.Biol., 18, 2011
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4U1F
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![BU of 4u1f by Molmil](/molmil-images/mine/4u1f) | |
2XEN
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![BU of 2xen by Molmil](/molmil-images/mine/2xen) | Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module. | Descriptor: | 1,2-ETHANEDIOL, METHANOL, NI1C MUT4, ... | Authors: | Kramer, M, Wetzel, S.K, Pluckthun, A, Mittl, P, Grutter, M. | Deposit date: | 2010-05-17 | Release date: | 2010-08-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module. J.Mol.Biol., 404, 2010
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4UBJ
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![BU of 4ubj by Molmil](/molmil-images/mine/4ubj) | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 5.55 MGy at 100K | Descriptor: | DIETHYL HYDROGEN PHOSPHATE, E3 | Authors: | Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G. | Deposit date: | 2014-08-13 | Release date: | 2015-08-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
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4UBM
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![BU of 4ubm by Molmil](/molmil-images/mine/4ubm) | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 11.11 MGy at 100K | Descriptor: | DIETHYL HYDROGEN PHOSPHATE, E3 | Authors: | Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G. | Deposit date: | 2014-08-13 | Release date: | 2015-08-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
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4U2U
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![BU of 4u2u by Molmil](/molmil-images/mine/4u2u) | |
8S2E
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![BU of 8s2e by Molmil](/molmil-images/mine/8s2e) | Fab4251-DS-SOSIP complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Nortier, P, Perez, L. | Deposit date: | 2024-02-17 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | RAIN: a Machine Learning-based identification for HIV-1 bNAbs. Res Sq, 2024
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2YD9
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![BU of 2yd9 by Molmil](/molmil-images/mine/2yd9) | Crystal structure of the N-terminal Ig1-3 module of Human Receptor Protein Tyrosine Phosphatase Sigma | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Coles, C.H, Shen, Y, Tenney, A.P, Siebold, C, Sutton, G.C, Lu, W, Gallagher, J.T, Jones, E.Y, Flanagan, J.G, Aricescu, A.R. | Deposit date: | 2011-03-18 | Release date: | 2011-04-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension. Science, 332, 2011
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2YGW
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![BU of 2ygw by Molmil](/molmil-images/mine/2ygw) | Crystal structure of human MCD | Descriptor: | 1,2-ETHANEDIOL, MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL, ... | Authors: | Vollmar, M, Puranik, S, Krojer, T, Savitsky, P, Allerston, C, Yue, W.W, Chaikuad, A, von Delft, F, Gileadi, O, Kavanagh, K, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Oppermann, U. | Deposit date: | 2011-04-21 | Release date: | 2012-02-15 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structures of Malonyl-Coenzyme a Decarboxylase Provide Insights Into its Catalytic Mechanism and Disease-Causing Mutations. Structure, 21, 2013
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8RQJ
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![BU of 8rqj by Molmil](/molmil-images/mine/8rqj) | |