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PDB: 45910 件

3OMH
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Crystal structure of PTPN22 in complex with SKAP-HOM pTyr75 peptide
分子名称: Src kinase-associated phosphoprotein 2, Tyrosine-protein phosphatase non-receptor type 22
著者Yu, X, Sun, J.-P, Zhang, S, Zhang, Z.-Y.
登録日2010-08-26
公開日2011-06-29
最終更新日2011-09-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate.
J.Biol.Chem., 286, 2011
6FP5
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Crystal structure of ZAD-domain of CG2712 protein from D.melanogaster
分子名称: CG2712, GLYCEROL, ZINC ION
著者Boyko, K.M, Nikolaeva, A.Y, Bonchuk, A.N, Kachalova, G.S, Georgiev, P.G, Popov, V.O.
登録日2018-02-09
公開日2019-08-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila.
Nucleic Acids Res., 49, 2021
4LN3
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BU of 4ln3 by Molmil
The crystal structure of hemagglutinin from a H7N9 influenza virus (A/Shanghai/1/2013)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J.
登録日2013-07-11
公開日2013-10-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Analysis of the Hemagglutinin from the Recent 2013 H7N9 Influenza Virus.
J.Virol., 87, 2013
4LN4
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The crystal structure of hemagglutinin form a h7n9 influenza virus (a/shanghai/1/2013) in complex with lstb
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J.
登録日2013-07-11
公開日2013-10-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Analysis of the Hemagglutinin from the Recent 2013 H7N9 Influenza Virus.
J.Virol., 87, 2013
4LMD
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Crystal structure of the JCV large t-antigen origin binding domain
分子名称: CITRATE ANION, GLYCEROL, Large T antigen
著者Meinke, G, Bohm, A, Bullock, P.
登録日2013-07-10
公開日2014-04-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
Plos Pathog., 10, 2014
1XUB
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BU of 1xub by Molmil
Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens
分子名称: Phenazine biosynthesis protein phzF, SULFATE ION
著者Blankenfeldt, W, Kuzin, A.P, Skarina, T, Korniyenko, Y, Tong, L, Bayer, P, Janning, P, Thomashow, L.S, Mavrodi, D.V.
登録日2004-10-26
公開日2004-11-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens
PROC.NATL.ACAD.SCI.USA, 101, 2004
4QDP
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BU of 4qdp by Molmil
Joint X-ray and neutron structure of Streptomyces rubiginosus D-xylose isomerase in complex with two Cd2+ ions and cyclic beta-L-arabinose
分子名称: CADMIUM ION, Xylose isomerase, beta-L-arabinopyranose
著者Kovalevsky, A.Y, Langan, P.
登録日2014-05-14
公開日2014-09-03
最終更新日2024-02-28
実験手法NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION
主引用文献L-Arabinose Binding, Isomerization, and Epimerization by D-Xylose Isomerase: X-Ray/Neutron Crystallographic and Molecular Simulation Study.
Structure, 22, 2014
8G55
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Temperature-dependent structures of tau aggregates
分子名称: Microtubule-associated protein tau
著者El Mammeri, N, Duan, P, Dregni, A.J, Hong, M.
登録日2023-02-11
公開日2023-06-07
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Amyloid fibril structures of tau: Conformational plasticity of the second microtubule-binding repeat.
Sci Adv, 9, 2023
4LQ6
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BU of 4lq6 by Molmil
Crystal structure of Rv3717 reveals a novel amidase from M. tuberculosis
分子名称: CHLORIDE ION, N-acetymuramyl-L-alanine amidase-related protein, PLATINUM (II) ION, ...
著者Kumar, A, Kumar, S, Kumar, D, Mishra, A, Dewangan, R.P, Shrivastava, P, Ramachandran, S, Taneja, B.
登録日2013-07-17
公開日2013-12-04
最終更新日2014-01-15
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 69, 2013
7X5L
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BU of 7x5l by Molmil
Tir-dsDNA complex, the initial binding state
分子名称: DNA (5'-D(*AP*TP*AP*AP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*TP*AP*AP*TP*TP*AP*A)-3'), Flax rust resistance protein
著者Tan, Y, Xu, C, Yu, D, Song, W, Wu, B, Schulze-Lefert, P, Chai, J.
登録日2022-03-04
公開日2022-06-01
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death.
Cell, 185, 2022
3OM4
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Crystal structure of B. megaterium levansucrase mutant K373A
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Levansucrase, ...
著者Strube, C.P, Homann, A, Gamer, M, Jahn, D, Seibel, J, Heinz, D.W.
登録日2010-08-26
公開日2011-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of B. megaterium levansucrase mutant K373A
To be Published
4QE1
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BU of 4qe1 by Molmil
Room temperature X-ray structure of D-xylose isomerase in complex with two Cd2+ ions and L-ribulose
分子名称: CADMIUM ION, Xylose isomerase, alpha-L-ribulofuranose
著者Kovalevsky, A.Y, Langan, P.
登録日2014-05-15
公開日2014-09-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献L-Arabinose Binding, Isomerization, and Epimerization by D-Xylose Isomerase: X-Ray/Neutron Crystallographic and Molecular Simulation Study.
Structure, 22, 2014
8DB3
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BU of 8db3 by Molmil
Crystal structure of KaiC with truncated C-terminal coiled-coil domain
分子名称: ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC
著者Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D.
登録日2022-06-14
公開日2023-03-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献From primordial clocks to circadian oscillators.
Nature, 616, 2023
8G54
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BU of 8g54 by Molmil
Temperature-dependent structures of tau aggregates
分子名称: Microtubule-associated protein tau
著者El Mammeri, N, Duan, P, Dregni, A.J, Hong, M.
登録日2023-02-11
公開日2023-06-07
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Amyloid fibril structures of tau: Conformational plasticity of the second microtubule-binding repeat.
Sci Adv, 9, 2023
4LRO
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BU of 4lro by Molmil
Crystal structure of spermidine inhibited Ribosome inactivating protein from Momordica balsamina
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SPERMIDINE, ...
著者Yamini, S, Pandey, S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
登録日2013-07-20
公開日2013-08-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure of spermidine inhibited Ribosome inactivating protein from Momordica balsamina
To be Published
8GBE
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BU of 8gbe by Molmil
Structure of a viral gasdermin protein A47 from Eptesipox virus
分子名称: Protein A47
著者Johnson, A.G, Kranzusch, P.J.
登録日2023-02-25
公開日2023-03-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses.
Biorxiv, 2023
8GBD
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BU of 8gbd by Molmil
Homo sapiens Zalpha mutant - P193A
分子名称: Double-stranded RNA-specific adenosine deaminase
著者Langeberg, C.J, Vogeli, B, Nichols, P.J, Henen, M, Vicens, Q.
登録日2023-02-25
公開日2023-03-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Differential Structural Features of Two Mutant ADAR1p150 Z alpha Domains Associated with Aicardi-Goutieres Syndrome.
J.Mol.Biol., 435, 2023
1URC
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BU of 1urc by Molmil
Cyclin A binding groove inhibitor Ace-Arg-Lys-Leu-Phe-Gly
分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, PEPTIDE INHIBITOR
著者Kontopidis, G, Andrews, M, McInnes, C, Cowan, A, Powers, H, Innes, L, Plater, A, Griffiths, G, Paterson, D, Zheleva, D, Lane, D, Green, S, Walkinshaw, M, Fischer, P.
登録日2003-10-28
公開日2003-10-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Design, synthesis, biological activity and structural analysis of cyclic peptide inhibitors targeting the substrate recruitment site of cyclin-dependent kinase complexes.
Org. Biomol. Chem., 2, 2004
8DIP
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BU of 8dip by Molmil
The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023030
分子名称: (2P)-5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-oxo-2-[3-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ...
著者Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W.
登録日2022-06-29
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
Eur.J.Med.Chem., 247, 2023
3ZHH
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BU of 3zhh by Molmil
X-ray structure of the full-length beta-lactamase from M.tuberculosis
分子名称: BETA-LACTAMASE, SULFATE ION
著者Feiler, C, Fisher, A.C, Marrichi, M.J, Wright, L, Schmidpeter, P.A.M, Blankenfeldt, W, Pavelka, M, DeLisa, M.P.
登録日2012-12-21
公開日2013-09-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Directed Evolution of Mycobacterium Tuberculosis Beta-Lactamase Reveals Gatekeeper Residue that Regulates Antibiotic Resistance and Catalytic Efficiency.
Plos One, 8, 2013
8GBC
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Homo sapiens Zalpha mutant - N173S
分子名称: Double-stranded RNA-specific adenosine deaminase
著者Langeberg, C.J, Nichols, P.J, Henen, M, Vicens, Q, Vogeli, B.
登録日2023-02-25
公開日2023-03-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Differential Structural Features of Two Mutant ADAR1p150 Z alpha Domains Associated with Aicardi-Goutieres Syndrome.
J.Mol.Biol., 435, 2023
3T22
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BU of 3t22 by Molmil
Crystal structure of OxyR mutant from Porphyromonas gingivalis
分子名称: Redox-sensitive transcriptional activator OxyR
著者Svintradze, D.V, Wright, H.T, Lewis, J.P.
登録日2011-07-22
公開日2013-04-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of the Porphyromonas gingivalis OxyR regulatory domain explain differences in expression of the OxyR regulon in Escherichia coli and P. gingivalis.
Acta Crystallogr.,Sect.D, 69, 2013
5A7R
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BU of 5a7r by Molmil
Human poly(ADP-ribose) glycohydrolase in complex with synthetic dimeric ADP-ribose
分子名称: BETA-MERCAPTOETHANOL, GLYCEROL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, ...
著者Lambrecht, M.J, Brichacek, M, Barkauskaite, E, Ariza, A, Ahel, I, Hergenrother, P.J.
登録日2015-07-09
公開日2015-07-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Synthesis of Dimeric Adp-Ribose and its Structure with Human Poly(Adp-Ribose) Glycohydrolase.
J.Am.Chem.Soc., 137, 2015
5A22
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Structure of the L protein of vesicular stomatitis virus from electron cryomicroscopy
分子名称: VESICULAR STOMATITIS VIRUS L POLYMERASE, ZINC ION
著者Liang, B, Li, Z, Jenni, S, Rameh, A.A, Morin, B.M, Grant, T, Grigorieff, N, Harrison, S.C, Whelan, S.P.J.
登録日2015-05-06
公開日2015-08-19
最終更新日2019-04-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.
Cell(Cambridge,Mass.), 162, 2015
5PMD
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BU of 5pmd by Molmil
PanDDA analysis group deposition -- Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 171)
分子名称: 1,2-ETHANEDIOL, Lysine-specific demethylase 4D, MAGNESIUM ION, ...
著者Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Szykowska, A, Burgess-Brown, N, Brennan, P.E, Cox, O, Oppermann, U, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F.
登録日2017-02-07
公開日2017-03-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Nat Commun, 8, 2017

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