4LMD
Crystal structure of the JCV large t-antigen origin binding domain
Summary for 4LMD
| Entry DOI | 10.2210/pdb4lmd/pdb |
| Related | 4LIF 4LMD |
| Descriptor | Large T antigen, GLYCEROL, CITRATE ANION, ... (4 entities in total) |
| Functional Keywords | origin binding domain, dna replication, hydrolase |
| Biological source | JC polyomavirus (JCPyV) |
| Cellular location | Host nucleus (By similarity): P03072 |
| Total number of polymer chains | 2 |
| Total formula weight | 30903.17 |
| Authors | Meinke, G.,Bohm, A.,Bullock, P. (deposition date: 2013-07-10, release date: 2014-04-02, Last modification date: 2024-02-28) |
| Primary citation | Meinke, G.,Phelan, P.J.,Kalekar, R.,Shin, J.,Archambault, J.,Bohm, A.,Bullock, P.A. Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain. Plos Pathog., 10:e1003966-e1003966, 2014 Cited by PubMed: 24586168DOI: 10.1371/journal.ppat.1003966 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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