7ZU1
| Crystal structure of mutant AR-LBD (V758A) bound to dihydrotestosterone | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ... | 著者 | Alegre-Marti, A, Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P. | 登録日 | 2022-05-11 | 公開日 | 2023-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance. Sci Adv, 9, 2023
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1TND
| THE 2.2 ANGSTROMS CRYSTAL STRUCTURE OF TRANSDUCIN-ALPHA COMPLEXED WITH GTP GAMMA S | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CACODYLATE ION, MAGNESIUM ION, ... | 著者 | Noel, J.P, Hamm, H.E, Sigler, P.B. | 登録日 | 1994-03-31 | 公開日 | 1994-07-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S. Nature, 366, 1993
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6PYF
| Sex Hormone-binding globulin mutant E176K in complex with Estradiol | 分子名称: | CALCIUM ION, ESTRADIOL, Sex hormone-binding globulin | 著者 | Round, P.W, Wu, T.S, Das, S, Van Petegem, F. | 登録日 | 2019-07-29 | 公開日 | 2019-12-25 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity. J.Biol.Chem., 295, 2020
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8T5L
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7BLV
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2LIA
| Solution NMR structure of a DNA dodecamer containing the 7-aminomethyl-7-deaza-2'-deoxyguanosine adduct | 分子名称: | DNA (5'-D(*GP*AP*GP*AP*(2LA)P*CP*GP*CP*TP*CP*TP*C)-3') | 著者 | Szulik, M.W, Ganguly, M, Wang, R, Gold, B, Stone, M.P. | 登録日 | 2011-08-26 | 公開日 | 2012-08-29 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Site-Specific Stabilization of DNA by a Tethered Major Groove Amine, 7-Aminomethyl-7-deaza-2'-deoxyguanosine. Biochemistry, 52, 2013
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7TBF
| Locally refined region of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-61.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ... | 著者 | Zhou, T, Tsybovsky, T, Kwong, P.D. | 登録日 | 2021-12-21 | 公開日 | 2022-03-30 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529. Science, 376, 2022
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7BM0
| Crystal structure of the tick-borne encephalitis virus NS3 helicase in complex with AMPPNP | 分子名称: | MANGANESE (II) ION, NS3 helicase domain, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Anindita, P.D, Grinkevich, P, Franta, Z. | 登録日 | 2021-01-19 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic insight into the RNA-stimulated ATPase activity of tick-borne encephalitis virus helicase. J.Biol.Chem., 298, 2022
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4NHH
| Structure of 2G12 IgG Dimer | 分子名称: | 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein | 著者 | Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J. | 登録日 | 2013-11-05 | 公開日 | 2014-02-26 | 実験手法 | X-RAY DIFFRACTION (6.5 Å) | 主引用文献 | Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12. Cell Rep, 5, 2013
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4IS4
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1O4M
| CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH MALONICACID. | 分子名称: | MALONIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC | 著者 | Lange, G, Loenze, P, Liesum, A. | 登録日 | 2003-06-15 | 公開日 | 2004-02-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
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3GZQ
| HUMAN SOD1 A4V Metal-free Variant | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn] | 著者 | Galaleldeen, A, Taylor, A.B, Whitson, L.J, Hart, P.J. | 登録日 | 2009-04-07 | 公開日 | 2009-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | 主引用文献 | Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A. Arch.Biochem.Biophys., 492, 2009
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6G79
| Coupling specificity of heterotrimeric Go to the serotonin 5-HT1B receptor | 分子名称: | 2-[5-[2-[4-(4-cyanophenyl)piperazin-1-yl]-2-oxidanylidene-ethoxy]-1~{H}-indol-3-yl]ethylazanium, 5-hydroxytryptamine receptor 1B, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Garcia-Nafria, J, Nehme, R, Edwards, P, Tate, C.G. | 登録日 | 2018-04-05 | 公開日 | 2018-06-20 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Cryo-EM structure of the serotonin 5-HT1Breceptor coupled to heterotrimeric Go. Nature, 558, 2018
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4BR9
| Legionella pneumophila NTPDase1 crystal form II, closed, apo | 分子名称: | ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, GLYCEROL, SULFATE ION | 著者 | Zebisch, M, Schaefer, P, Lauble, P, Straeter, N. | 登録日 | 2013-06-04 | 公開日 | 2013-07-17 | 最終更新日 | 2017-08-23 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases Structure, 21, 2013
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7TC9
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1EB3
| YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 4,7-DIOXOSEBACIC ACID COMPLEX | 分子名称: | 4,7-DIOXOSEBACIC ACID, 5-AMINOLAEVULINIC ACID DEHYDRATASE, ZINC ION | 著者 | Erskine, P.T, Coates, L, Newbold, R, Brindley, A.A, Stauffer, F, Wood, S.P, Warren, M.J, Cooper, J.B, Shoolingin-Jordan, P.M, Neier, R. | 登録日 | 2001-07-18 | 公開日 | 2001-08-02 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors FEBS Lett., 503, 2001
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8VCV
| Lineage IV Lassa virus glycoprotein (Josiah) in complex with rabbit polyclonal antibody (GPC-C epitope) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Brouwer, P.J.M, Perrett, H.R, Ward, A.B. | 登録日 | 2023-12-14 | 公開日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses. Cell Rep, 43, 2024
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7ZLF
| Mutant L39Y-L58F of recombinant bovine beta-lactoglobulin in complex with endogenous fatty acid | 分子名称: | 1,2-ETHANEDIOL, Beta-lactoglobulin, CHLORIDE ION, ... | 著者 | Loch, J.I, Kurpiewska, K, Bonarek, P. | 登録日 | 2022-04-14 | 公開日 | 2023-04-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | beta-Lactoglobulin variants as potential carriers of pramoxine: Comprehensive structural and biophysical studies. J.Mol.Recognit., 36, 2023
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1TRJ
| Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome | 分子名称: | Guanine nucleotide-binding protein beta subunit-like protein, Helix 39 of 18S rRNA, Helix 40 of 18S rRNA | 著者 | Sengupta, J, Nilsson, J, Gursky, R, Spahn, C.M, Nissen, P, Frank, J. | 登録日 | 2004-06-21 | 公開日 | 2004-09-28 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (11.7 Å) | 主引用文献 | Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM Nat.Struct.Mol.Biol., 11, 2004
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4BRG
| Legionella pneumophila NTPDase1 crystal form II (closed) in complex with MG GMPPNP | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, ... | 著者 | Zebisch, M, Schaefer, P, Lauble, P, Straeter, N. | 登録日 | 2013-06-04 | 公開日 | 2013-07-17 | 最終更新日 | 2013-12-25 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases Structure, 21, 2013
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2I60
| Crystal structure of [Phe23]M47, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 GP120 envelope glycoprotein and anti-HIV-1 antibody 17B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B HEAVY CHAIN, ANTIBODY 17B LIGHT CHAIN, ... | 著者 | Huang, C.-C, Kwong, P.D. | 登録日 | 2006-08-26 | 公開日 | 2006-10-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein. J.Mol.Biol., 382, 2008
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4CBT
| Design, synthesis, and biological evaluation of potent and selective Class IIa HDAC inhibitors as a potential therapy for Huntington's disease | 分子名称: | (1R,2R,3R)-2-[4-(5-fluoranylpyrimidin-2-yl)phenyl]-N-oxidanyl-3-phenyl-cyclopropane-1-carboxamide, HISTONE DEACETYLASE 4, ZINC ION | 著者 | Burli, R.W, Luckhurst, C.A, Aziz, O, Matthews, K.L, Yates, D, Lyons, K.A, Beconi, M, McAllister, G, Breccia, P, Stott, A.J, Penrose, S.D, Wall, M, Lamers, M, Leonard, P, Mueller, I, Richardson, C.M, Jarvis, R, Stones, L, Hughes, S, Wishart, G, Haughan, A.F, O'Connell, C, Mead, T, McNeil, H, Vann, J, Mangette, J, Maillard, M, Beaumont, V, Munoz-Sanjuan, I, Dominguez, C. | 登録日 | 2013-10-16 | 公開日 | 2013-12-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Design, synthesis, and biological evaluation of potent and selective class IIa histone deacetylase (HDAC) inhibitors as a potential therapy for Huntington's disease. J. Med. Chem., 56, 2013
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6PU5
| MicroED structure of proteinase K recorded on CetaD | 分子名称: | CALCIUM ION, Proteinase K | 著者 | Hattne, J, Martynowycz, M.W, Penzcek, P.A, Gonen, T. | 登録日 | 2019-07-17 | 公開日 | 2019-08-28 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.7 Å) | 主引用文献 | MicroED with the Falcon III direct electron detector. Iucrj, 6, 2019
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8VE8
| Lineage IV Lassa virus glycoprotein (Josiah) in complex with rabbit polyclonal antibody (GP1-A epitope) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Brouwer, P.J.M, Perrett, H.R, Ward, A.B. | 登録日 | 2023-12-18 | 公開日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses. Cell Rep, 43, 2024
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7ZPN
| Crystal Structure of IscR from Dinoroseobacter shibae | 分子名称: | GLYCEROL, HTH-type transcriptional regulator, SULFATE ION | 著者 | Lukat, P, Ploetzky, L, Blankenfeldt, W, Jahn, D, Haertig, E. | 登録日 | 2022-04-28 | 公開日 | 2023-04-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Dinoroseobacter shibae IscR homolog acts as a repressor for iron acquisition genes To Be Published
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