7ZU1
 
 | | Crystal structure of mutant AR-LBD (V758A) bound to dihydrotestosterone | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ... | | 著者 | Alegre-Marti, A, Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P. | | 登録日 | 2022-05-11 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
Sci Adv, 9, 2023
|
|
1TND
 | | THE 2.2 ANGSTROMS CRYSTAL STRUCTURE OF TRANSDUCIN-ALPHA COMPLEXED WITH GTP GAMMA S | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CACODYLATE ION, MAGNESIUM ION, ... | | 著者 | Noel, J.P, Hamm, H.E, Sigler, P.B. | | 登録日 | 1994-03-31 | | 公開日 | 1994-07-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S.
Nature, 366, 1993
|
|
6PYF
 | | Sex Hormone-binding globulin mutant E176K in complex with Estradiol | | 分子名称: | CALCIUM ION, ESTRADIOL, Sex hormone-binding globulin | | 著者 | Round, P.W, Wu, T.S, Das, S, Van Petegem, F. | | 登録日 | 2019-07-29 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity.
J.Biol.Chem., 295, 2020
|
|
8T5L
 | |
7BLV
 | |
2LIA
 | | Solution NMR structure of a DNA dodecamer containing the 7-aminomethyl-7-deaza-2'-deoxyguanosine adduct | | 分子名称: | DNA (5'-D(*GP*AP*GP*AP*(2LA)P*CP*GP*CP*TP*CP*TP*C)-3') | | 著者 | Szulik, M.W, Ganguly, M, Wang, R, Gold, B, Stone, M.P. | | 登録日 | 2011-08-26 | | 公開日 | 2012-08-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Site-Specific Stabilization of DNA by a Tethered Major Groove Amine, 7-Aminomethyl-7-deaza-2'-deoxyguanosine.
Biochemistry, 52, 2013
|
|
7TBF
 | | Locally refined region of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-61.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ... | | 著者 | Zhou, T, Tsybovsky, T, Kwong, P.D. | | 登録日 | 2021-12-21 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
|
|
7BM0
 | | Crystal structure of the tick-borne encephalitis virus NS3 helicase in complex with AMPPNP | | 分子名称: | MANGANESE (II) ION, NS3 helicase domain, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Anindita, P.D, Grinkevich, P, Franta, Z. | | 登録日 | 2021-01-19 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanistic insight into the RNA-stimulated ATPase activity of tick-borne encephalitis virus helicase.
J.Biol.Chem., 298, 2022
|
|
4NHH
 | | Structure of 2G12 IgG Dimer | | 分子名称: | 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein | | 著者 | Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J. | | 登録日 | 2013-11-05 | | 公開日 | 2014-02-26 | | 実験手法 | X-RAY DIFFRACTION (6.5 Å) | | 主引用文献 | Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Cell Rep, 5, 2013
|
|
4IS4
 | |
1O4M
 | | CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH MALONICACID. | | 分子名称: | MALONIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC | | 著者 | Lange, G, Loenze, P, Liesum, A. | | 登録日 | 2003-06-15 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
J.Med.Chem., 46, 2003
|
|
3GZQ
 | | HUMAN SOD1 A4V Metal-free Variant | | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn] | | 著者 | Galaleldeen, A, Taylor, A.B, Whitson, L.J, Hart, P.J. | | 登録日 | 2009-04-07 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | | 主引用文献 | Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A.
Arch.Biochem.Biophys., 492, 2009
|
|
6G79
 | | Coupling specificity of heterotrimeric Go to the serotonin 5-HT1B receptor | | 分子名称: | 2-[5-[2-[4-(4-cyanophenyl)piperazin-1-yl]-2-oxidanylidene-ethoxy]-1~{H}-indol-3-yl]ethylazanium, 5-hydroxytryptamine receptor 1B, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Garcia-Nafria, J, Nehme, R, Edwards, P, Tate, C.G. | | 登録日 | 2018-04-05 | | 公開日 | 2018-06-20 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Cryo-EM structure of the serotonin 5-HT1Breceptor coupled to heterotrimeric Go.
Nature, 558, 2018
|
|
4BR9
 | | Legionella pneumophila NTPDase1 crystal form II, closed, apo | | 分子名称: | ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, GLYCEROL, SULFATE ION | | 著者 | Zebisch, M, Schaefer, P, Lauble, P, Straeter, N. | | 登録日 | 2013-06-04 | | 公開日 | 2013-07-17 | | 最終更新日 | 2017-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
|
|
7TC9
 | |
1EB3
 | | YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 4,7-DIOXOSEBACIC ACID COMPLEX | | 分子名称: | 4,7-DIOXOSEBACIC ACID, 5-AMINOLAEVULINIC ACID DEHYDRATASE, ZINC ION | | 著者 | Erskine, P.T, Coates, L, Newbold, R, Brindley, A.A, Stauffer, F, Wood, S.P, Warren, M.J, Cooper, J.B, Shoolingin-Jordan, P.M, Neier, R. | | 登録日 | 2001-07-18 | | 公開日 | 2001-08-02 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors
FEBS Lett., 503, 2001
|
|
8VCV
 | | Lineage IV Lassa virus glycoprotein (Josiah) in complex with rabbit polyclonal antibody (GPC-C epitope) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Brouwer, P.J.M, Perrett, H.R, Ward, A.B. | | 登録日 | 2023-12-14 | | 公開日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.
Cell Rep, 43, 2024
|
|
7ZLF
 | | Mutant L39Y-L58F of recombinant bovine beta-lactoglobulin in complex with endogenous fatty acid | | 分子名称: | 1,2-ETHANEDIOL, Beta-lactoglobulin, CHLORIDE ION, ... | | 著者 | Loch, J.I, Kurpiewska, K, Bonarek, P. | | 登録日 | 2022-04-14 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | beta-Lactoglobulin variants as potential carriers of pramoxine: Comprehensive structural and biophysical studies.
J.Mol.Recognit., 36, 2023
|
|
1TRJ
 | | Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome | | 分子名称: | Guanine nucleotide-binding protein beta subunit-like protein, Helix 39 of 18S rRNA, Helix 40 of 18S rRNA | | 著者 | Sengupta, J, Nilsson, J, Gursky, R, Spahn, C.M, Nissen, P, Frank, J. | | 登録日 | 2004-06-21 | | 公開日 | 2004-09-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (11.7 Å) | | 主引用文献 | Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM
Nat.Struct.Mol.Biol., 11, 2004
|
|
4BRG
 | | Legionella pneumophila NTPDase1 crystal form II (closed) in complex with MG GMPPNP | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, ... | | 著者 | Zebisch, M, Schaefer, P, Lauble, P, Straeter, N. | | 登録日 | 2013-06-04 | | 公開日 | 2013-07-17 | | 最終更新日 | 2013-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
|
|
2I60
 | | Crystal structure of [Phe23]M47, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 GP120 envelope glycoprotein and anti-HIV-1 antibody 17B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B HEAVY CHAIN, ANTIBODY 17B LIGHT CHAIN, ... | | 著者 | Huang, C.-C, Kwong, P.D. | | 登録日 | 2006-08-26 | | 公開日 | 2006-10-10 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein.
J.Mol.Biol., 382, 2008
|
|
4CBT
 | | Design, synthesis, and biological evaluation of potent and selective Class IIa HDAC inhibitors as a potential therapy for Huntington's disease | | 分子名称: | (1R,2R,3R)-2-[4-(5-fluoranylpyrimidin-2-yl)phenyl]-N-oxidanyl-3-phenyl-cyclopropane-1-carboxamide, HISTONE DEACETYLASE 4, ZINC ION | | 著者 | Burli, R.W, Luckhurst, C.A, Aziz, O, Matthews, K.L, Yates, D, Lyons, K.A, Beconi, M, McAllister, G, Breccia, P, Stott, A.J, Penrose, S.D, Wall, M, Lamers, M, Leonard, P, Mueller, I, Richardson, C.M, Jarvis, R, Stones, L, Hughes, S, Wishart, G, Haughan, A.F, O'Connell, C, Mead, T, McNeil, H, Vann, J, Mangette, J, Maillard, M, Beaumont, V, Munoz-Sanjuan, I, Dominguez, C. | | 登録日 | 2013-10-16 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Design, synthesis, and biological evaluation of potent and selective class IIa histone deacetylase (HDAC) inhibitors as a potential therapy for Huntington's disease.
J. Med. Chem., 56, 2013
|
|
6PU5
 | | MicroED structure of proteinase K recorded on CetaD | | 分子名称: | CALCIUM ION, Proteinase K | | 著者 | Hattne, J, Martynowycz, M.W, Penzcek, P.A, Gonen, T. | | 登録日 | 2019-07-17 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.7 Å) | | 主引用文献 | MicroED with the Falcon III direct electron detector.
Iucrj, 6, 2019
|
|
8VE8
 | | Lineage IV Lassa virus glycoprotein (Josiah) in complex with rabbit polyclonal antibody (GP1-A epitope) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Brouwer, P.J.M, Perrett, H.R, Ward, A.B. | | 登録日 | 2023-12-18 | | 公開日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.
Cell Rep, 43, 2024
|
|
7ZPN
 | | Crystal Structure of IscR from Dinoroseobacter shibae | | 分子名称: | GLYCEROL, HTH-type transcriptional regulator, SULFATE ION | | 著者 | Lukat, P, Ploetzky, L, Blankenfeldt, W, Jahn, D, Haertig, E. | | 登録日 | 2022-04-28 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Dinoroseobacter shibae IscR homolog acts as a repressor for iron acquisition genes
To Be Published
|
|
