6G79
Coupling specificity of heterotrimeric Go to the serotonin 5-HT1B receptor
Summary for 6G79
Entry DOI | 10.2210/pdb6g79/pdb |
EMDB information | 4358 |
Descriptor | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(o) subunit alpha, ... (5 entities in total) |
Functional Keywords | g-protein coupled receptor, 5-ht1b, mini-go, serotonin, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 111964.40 |
Authors | Garcia-Nafria, J.,Nehme, R.,Edwards, P.,Tate, C.G. (deposition date: 2018-04-05, release date: 2018-06-20, Last modification date: 2019-12-11) |
Primary citation | Garcia-Nafria, J.,Nehme, R.,Edwards, P.C.,Tate, C.G. Cryo-EM structure of the serotonin 5-HT1Breceptor coupled to heterotrimeric Go. Nature, 558:620-623, 2018 Cited by PubMed: 29925951DOI: 10.1038/s41586-018-0241-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.78 Å) |
Structure validation
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