6HIV
 
 | | Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the complete mitoribosome | | 分子名称: | 12S rRNA, 50S ribosomal protein L13, putative, ... | | 著者 | Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boerhringer, D, Schneider, A, Ban, N. | | 登録日 | 2018-08-31 | | 公開日 | 2018-10-03 | | 最終更新日 | 2018-11-07 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018
|
|
6TRA
 | | Cryo- EM structure of the Thermosynechococcus elongatus photosystem I in the presence of cytochrome c6 | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | | 著者 | Koelsch, A, Radon, C, Baumert, A, Buerger, J, Miehlke, T, Lisdat, F, Zouni, A, Wendler, P. | | 登録日 | 2019-12-18 | | 公開日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Current limits of structural biology: The transient interaction between cytochrome c6 and photosystem I
Curr.Opin.Struct.Biol., 2, 2020
|
|
6NKL
 | | 2.2 A resolution structure of VapBC-1 from nontypeable Haemophilus influenzae | | 分子名称: | Antitoxin VapB1, Ribonuclease VapC | | 著者 | Lovell, S, Kashipathy, M.M, Battaile, K.P, Molinaro, A.L, Daines, D.A. | | 登録日 | 2019-01-07 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of VapBC-1 from Nontypeable Haemophilus influenzae and the Effect of PIN Domain Mutations on Survival during Infection.
J.Bacteriol., 201, 2019
|
|
4A3M
 | | RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP | | 分子名称: | 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP* TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*GP*GP*A)-3', ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
|
|
6GYM
 | | Structure of a yeast closed complex with distorted DNA (CCdist) | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | | 登録日 | 2018-06-30 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Promoter Distortion and Opening in the RNA Polymerase II Cleft.
Mol. Cell, 73, 2019
|
|
7UZ9
 | |
8R5V
 | | Crystal structure of bovine pancreatic ribonuclease A in complex with [Sp-PS]-mU-dT dinucleotide | | 分子名称: | 1-[(2~{R},4~{S},5~{R})-5-[[[(2~{R},6~{S})-2-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-6-(hydroxymethyl)morpholin-4-yl]-oxidanyl-phosphinothioyl]oxymethyl]-4-oxidanyl-oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione, DICHLORO-ACETIC ACID, Ribonuclease pancreatic | | 著者 | Dolot, R, Jastrzebska, K, Antonczyk, P. | | 登録日 | 2023-11-17 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synthesis of P-stereodefined morpholino dinucleoside-3',6'-thiophosphoramidates using unexpected activator.
To Be Published
|
|
7UZ8
 | |
7UZA
 | |
6H12
 | | Crystal structure of TcACHE complexed to 1-(6-Oxo-1,2,3,4,6,10b-hexahydropyrido[2,1-a]isoindol-10-yl)-3-(4-(((1-(2-((1,2,3,4-tetrahydroacridin-9-yl)amino)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)methyl)pyridin-2-yl)urea | | 分子名称: | 1,2-ETHANEDIOL, 1-[4-[[1-[2-(1,2,3,4,4~{a},9~{a}-hexahydroacridin-9-ylamino)ethyl]-1,2,3-triazol-4-yl]methoxymethyl]pyridin-2-yl]-3-[(10~{b}~{R})-6-oxidanylidene-2,3,4,10~{b}-tetrahydro-1~{H}-pyrido[2,1-a]isoindol-10-yl]urea, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | 著者 | Coquelle, N, Colletier, J.P. | | 登録日 | 2018-07-10 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3.
Eur.J.Med.Chem., 168, 2019
|
|
7UZ5
 | |
4AME
 | | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T18A | | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | | 登録日 | 1999-01-24 | | 公開日 | 1999-04-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function.
J.Biol.Chem., 274, 1999
|
|
7UZ6
 | |
5GRO
 | | Crystal structure of the N-terminal anticodon-binding domain of non-discriminating aspartyl-tRNA synthetase from Helicobacter pylori | | 分子名称: | Aspartate--tRNA(Asp/Asn) ligase, GLYCEROL, IMIDAZOLE, ... | | 著者 | Songsiriritthigul, C, Fuengfuloy, P, Chen, C.-J, Suebka, S, Chuawong, P. | | 登録日 | 2016-08-12 | | 公開日 | 2017-02-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the N-terminal anticodon-binding domain of the nondiscriminating aspartyl-tRNA synthetase from Helicobacter pylori
Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
7UZ4
 | |
7UZ7
 | |
6T7L
 | | Crystal structure of AmpC from E.coli with Nacubactam (OP0595) | | 分子名称: | (2S,5R)-N-(2-aminoethoxy)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-lactamase, ... | | 著者 | Lang, P.A, Leissing, T.M, Schofield, C.J, Brem, J. | | 登録日 | 2019-10-22 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Structural Investigations of the Inhibition of Escherichia coli AmpC beta-Lactamase by Diazabicyclooctanes.
Antimicrob.Agents Chemother., 65, 2021
|
|
6NHJ
 | | Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development | | 分子名称: | Major capsid protein, Minor capsid protein, Small capsomere-interacting protein, ... | | 著者 | Liu, W, Dai, X.H, Jih, J, Chan, K, Trang, P, Yu, X.K, Balogun, R, Mei, Y, Liu, F.Y, Zhou, Z.H. | | 登録日 | 2018-12-22 | | 公開日 | 2019-03-06 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development.
PLoS Pathog., 15, 2019
|
|
1BA3
 | | FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM | | 分子名称: | LUCIFERASE, TRIBROMOMETHANE | | 著者 | Franks, N.P, Jenkins, A, Conti, E, Lieb, W.R, Brick, P. | | 登録日 | 1998-04-21 | | 公開日 | 1998-11-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the inhibition of firefly luciferase by a general anesthetic.
Biophys.J., 75, 1998
|
|
8AI6
 | | Crystal structure of radical SAM epimerase EpeE D210A mutant from Bacillus subtilis with [4Fe-4S] clusters, S-adenosyl-L-homocysteine and persulfurated cysteine bound | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... | | 著者 | Polsinelli, I, Legrand, P, Fyfe, C.D, Benjdia, A, Berteau, O. | | 登録日 | 2022-07-25 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme.
Nat.Chem.Biol., 20, 2024
|
|
8AI1
 | | Crystal structure of radical SAM epimerase EpeE from Bacillus subtilis with [4Fe-4S] clusters and S-adenosyl-L-homocysteine bound. | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... | | 著者 | Kubiak, X, Polsinelli, I, Chavas, L.M.G, Legrand, P, Fyfe, C.D, Benjdia, A, Berteau, O. | | 登録日 | 2022-07-25 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme.
Nat.Chem.Biol., 20, 2024
|
|
8AI4
 | | Crystal structure of radical SAM epimerase EpeE C223A mutant from Bacillus subtilis with [4Fe-4S] clusters, S-adenosyl-L-homocysteine and RiPP peptide 5 bound | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Polsinelli, I, Fyfe, C.D, Legrand, P, Kubiak, X, Chavas, L.M.G, Berteau, O, Benjdia, A. | | 登録日 | 2022-07-25 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme.
Nat.Chem.Biol., 20, 2024
|
|
6T35
 | | Crystal structure of AmpC from E.coli with Enmetazobactam (AAI-101) | | 分子名称: | Beta-lactamase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Lang, P.A, Leissing, T.M, Schofield, C.J, Brem, J. | | 登録日 | 2019-10-10 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Studies on enmetazobactam clarify mechanisms of widely used beta-lactamase inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
8AI3
 | | Crystal structure of radical SAM epimerase EpeE C223A mutant from Bacillus subtilis with [4Fe-4S] clusters and S-adenosyl-L-methionine bound | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, IRON/SULFUR CLUSTER, ... | | 著者 | Kubiak, X, Chavas, L.M.G, Legrand, P, Polsinelli, I, Fyfe, C.D, Benjdia, A, Berteau, O. | | 登録日 | 2022-07-25 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme.
Nat.Chem.Biol., 20, 2024
|
|
8AI2
 | | Crystal structure of radical SAM epimerase EpeE from Bacillus subtilis with [4Fe-4S] clusters, S-adenosyl-L-homocysteine and RiPP peptide 5 bound | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... | | 著者 | Polsinelli, I, Fyfe, C.D, Legrand, P, Kubiak, X, Chavas, L.M.G, Berteau, O, Benjdia, A. | | 登録日 | 2022-07-25 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | | 主引用文献 | Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme.
Nat.Chem.Biol., 20, 2024
|
|
