6NHJ

Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development

This is a large structure.

Summary for 6NHJ

EMDB information9367 9368 9369 9366
DescriptorMajor capsid protein, Tegument protein, Small capsomere-interacting protein, ... (5 entities in total)
Functional Keywordscryoem, beta-herpesvirus, murine cytomegalovirus, human cytomegalovirus, pp150, pul32, pm32, bacterial artificial chromosome-based mutagenesis, virus
Biological sourceMurine cytomegalovirus (strain Smith) (MuHV-1)
Total number of polymer chains55
Total molecular weight3727300.42
Authors
Liu, W.,Dai, X.H.,Jih, J.,Chan, K.,Trang, P.,Yu, X.K.,Balogun, R.,Mei, Y.,Liu, F.Y.,Zhou, Z.H. (deposition date: 2018-12-22, release date: 2019-03-06)
Primary citation
Liu, W.,Dai, X.,Jih, J.,Chan, K.,Trang, P.,Yu, X.,Balogun, R.,Mei, Y.,Liu, F.,Zhou, Z.H.
Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development.
PLoS Pathog., 15:e1007615-e1007615, 2019
PubMed: 30779794 (PDB entries with the same primary citation)
DOI: 10.1371/journal.ppat.1007615
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers17 0.4% 1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

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More Biological unit images

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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6nhj-assembly1.cif.gz [261.08 MB])