1C55
 
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8HGI
 | | Crystal structure of VNAR aGFP14 in complex with GFP | | 分子名称: | GFP, VNAR aGFP14, [2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC ACID | | 著者 | Zheng, P, Zhu, C, Jin, T. | | 登録日 | 2022-11-14 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Selection, identification and crystal structure of shark-derived single-domain antibodies against a green fluorescent protein.
Int.J.Biol.Macromol., 247, 2023
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5MYB
 | | Homodimerization of Tie2 Fibronectin-like domains 2 and 3 in space group P21 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiopoietin-1 receptor, ... | | 著者 | Leppanen, V.-M, Saharinen, P, Alitalo, K. | | 登録日 | 2017-01-26 | | 公開日 | 2017-04-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1XP1
 | | HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 15 | | 分子名称: | (2S,3R)-2-(4-{2-[(3R,4R)-3,4-DIMETHYLPYRROLIDIN-1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6- OL, Estrogen receptor | | 著者 | Fitzgerald, P.M.D, Sharma, N. | | 登録日 | 2004-10-07 | | 公開日 | 2004-12-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers.
Bioorg.Med.Chem.Lett., 15, 2005
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5MGB
 | | Crystal Structure of Rat Peroxisomal Multifunctional enzyme Type-1 (RPMFE1) Complexed with Acetoacetyl-CoA and NAD | | 分子名称: | ACETOACETYL-COENZYME A, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Kasaragod, P, Kiema, T.-R, Schmitz, W, Hiltunen, J.K, Wierenga, R.K. | | 登録日 | 2016-11-21 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural enzymology comparisons of multifunctional enzyme, type-1 (MFE1): the flexibility of its dehydrogenase part.
FEBS Open Bio, 7, 2017
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2P38
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1XRQ
 | | Crystal structure of active site F1-mutant E245Q soaked with peptide Phe-Leu | | 分子名称: | LEUCINE, Proline iminopeptidase | | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | | 登録日 | 2004-10-15 | | 公開日 | 2005-07-12 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum
J.Biol.Chem., 280, 2005
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5BRF
 | | Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor HPOP-GlcN | | 分子名称: | 2-deoxy-2-{[3-(4-hydroxyphenyl)propanoyl]amino}-alpha-D-glucopyranose, Glucokinase 1, putative | | 著者 | D'Antonio, E.L, Perry, K, Deinema, M.S, Kearns, S.P, Frey, T.A. | | 登録日 | 2015-05-30 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | | 主引用文献 | Structure-based approach to the identification of a novel group of selective glucosamine analogue inhibitors of Trypanosoma cruzi glucokinase.
Mol.Biochem.Parasitol., 204, 2016
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1C90
 | | Endo-Beta-N-Acetylglucosaminidase H, E132Q Mutant | | 分子名称: | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE H | | 著者 | Rao, V, Tao, C, Guan, C, Van Roey, P. | | 登録日 | 1999-07-30 | | 公開日 | 1999-11-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Mutations of endo-beta-N-acetylglucosaminidase H active site residues Assp130 and Glu132: activities and conformations.
Protein Sci., 8, 1999
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1FFS
 | | CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY FROM CRYSTALS SOAKED IN ACETYL PHOSPHATE | | 分子名称: | CHEMOTAXIS PROTEIN CHEA, CHEMOTAXIS PROTEIN CHEY, MANGANESE (II) ION | | 著者 | Gouet, P, Chinardet, N, Welch, M, Guillet, V, Birck, C, Mourey, L, Samama, J.-P. | | 登録日 | 2000-07-26 | | 公開日 | 2001-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Further insights into the mechanism of function of the response regulator CheY from crystallographic studies of the CheY--CheA(124--257) complex.
Acta Crystallogr.,Sect.D, 57, 2001
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1JZO
 | | DsbC C101S | | 分子名称: | THIOL:DISULFIDE INTERCHANGE PROTEIN DSBC | | 著者 | Haebel, P.W, Goldstone, D, Katzen, F, Beckwith, J, Metcalf, P. | | 登録日 | 2001-09-17 | | 公開日 | 2003-03-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | The Disulfide Bond Isomerase DsbC is Activated by an
Immunoglobulin-fold Thiol Oxidoreductase: Crystal Structure of the
DsbC-DsbDalpha complex.
Embo J., 21, 2002
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4YCU
 | | Crystal structure of cladosporin in complex with human lysyl-tRNA synthetase | | 分子名称: | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, GLYCEROL, LYSINE, ... | | 著者 | Fang, P, Wang, J, Guo, M. | | 登録日 | 2015-02-20 | | 公開日 | 2015-06-10 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor.
Chem. Biol., 22, 2015
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5BRH
 | | Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor DBT-GlcN | | 分子名称: | 2-deoxy-2-({[(1,1-dioxido-1-benzothiophen-2-yl)methoxy]carbonyl}amino)-beta-D-glucopyranose, Glucokinase 1, putative | | 著者 | D'Antonio, E.L, Perry, K, Deinema, M.S, Kearns, S.P, Frey, T.A. | | 登録日 | 2015-05-30 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-based approach to the identification of a novel group of selective glucosamine analogue inhibitors of Trypanosoma cruzi glucokinase.
Mol.Biochem.Parasitol., 204, 2016
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1XP9
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1XQW
 | | Crystal structure of F1-mutant S105A complex with PHE-LEU | | 分子名称: | LEUCINE, PHENYLALANINE, Proline iminopeptidase | | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | | 登録日 | 2004-10-13 | | 公開日 | 2005-07-12 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum
J.Biol.Chem., 280, 2005
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4A66
 | | Mutations in the neighbourhood of CotA-laccase trinuclear site: D116A mutant | | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, PEROXIDE ION, ... | | 著者 | Silva, C.S, Lindley, P.F, Bento, I. | | 登録日 | 2011-10-31 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The Role of Asp116 in the Reductive Cleavage of Dioxygen to Water in Cota Laccase: Assistance During the Proton Transfer Mechanism
Acta Crystallogr.,Sect.D, 68, 2012
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1N4R
 | | Protein Geranylgeranyltransferase type-I Complexed with a Geranylgeranylated KKKSKTKCVIL Peptide Product | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, ... | | 著者 | Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S. | | 登録日 | 2002-11-01 | | 公開日 | 2003-11-18 | | 最終更新日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
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4AMJ
 | | Turkey beta1 adrenergic receptor with stabilising mutations and bound biased agonist carvedilol | | 分子名称: | (2S)-1-(8H-CARBAZOL-4-YLOXY)-3-[2-(2-METHOXYPHENOXY)ETHYLAMINO]PROPAN-2-OL, BETA-1 ADRENERGIC RECEPTOR, HEGA-10, ... | | 著者 | Warne, T, Edwards, P.C, Leslie, A.G, Tate, C.G. | | 登録日 | 2012-03-12 | | 公開日 | 2012-05-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of a Stabilized Beta1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol
Structure, 20, 2012
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4B71
 | | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | | 分子名称: | (1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propan-1-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3 | | 著者 | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
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4APA
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1C92
 | | Endo-Beta-N-Acetylglucosaminidase H, E132A Mutant | | 分子名称: | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE H | | 著者 | Rao, V, Cui, T, Guan, C, Van Roey, P. | | 登録日 | 1999-07-30 | | 公開日 | 1999-11-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Mutations of endo-beta-N-acetylglucosaminidase H active site residues Asp130 and Glu132: activities and conformations.
Protein Sci., 8, 1999
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3ZS2
 | | TyrB25,NMePheB26,LysB28,ProB29-insulin analogue crystal structure | | 分子名称: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | | 著者 | Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A. | | 登録日 | 2011-06-21 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface.
J.Biol.Chem., 286, 2011
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5M6H
 | | Small Molecule inhibitors of IAP | | 分子名称: | 1-[3,3-dimethyl-6-(phenylmethyl)-2~{H}-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2~{R},5~{R})-5-methyl-2-morpholin-4-ylcarbonyl-piperazin-4-ium-1-yl]ethanone, E3 ubiquitin-protein ligase XIAP, SODIUM ION, ... | | 著者 | Williams, P.A. | | 登録日 | 2016-10-25 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP).
J. Med. Chem., 60, 2017
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7RXQ
 | | Crystal structure of junctophilin-2 in complex with a CaV1.1 peptide | | 分子名称: | ETHANOL, Junctophilin-2 N-terminal fragment, SULFATE ION, ... | | 著者 | Yang, Z, Panwar, P, Van Petegem, F. | | 登録日 | 2021-08-23 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1JAW
 | | AMINOPEPTIDASE P FROM E. COLI LOW PH FORM | | 分子名称: | ACETATE ION, AMINOPEPTIDASE P, MANGANESE (II) ION | | 著者 | Wilce, M.C.J, Bond, C.S, Lilley, P.E, Dixon, N.E, Freeman, H.C, Guss, J.M. | | 登録日 | 1997-12-22 | | 公開日 | 1999-04-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 95, 1998
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