4APA

Crystal structure of Mycobacterium tuberculosis fumarase (Rv1098c) S318A in apo form

Summary for 4APA

• Entry DOI: 10.2210/pdb4apa/pdb
• Related: 4ADL 4ADM 4APB
• Descriptor: FUMARATE HYDRATASE CLASS II (2 entities in total)
• Functional Keywords: hydrolase, metabolism
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Cellular location: Cytoplasm (By similarity): O53446
• Total number of polymer chains: 4
• Total formula weight: 200406.64

Authors

Bellinzoni, M.,Haouz, A.,Mechaly, A.E.,Alzari, P.M. (deposition date: 2012-03-31, release date: 2012-04-25, Last modification date: 2023-12-20)

• Primary citation: Mechaly, A.E.,Haouz, A.,Miras, I.,Barilone, N.,Weber, P.,Shepard, W.,Alzari, P.M.,Bellinzoni, M.; Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.; FEBS Lett., 586:1606-, 2012; PubMed: 22561013; DOI: 10.1016/J.FEBSLET.2012.04.034

Experimental method

X-RAY DIFFRACTION (2.04 Å)