1LQV
| Crystal structure of the Endothelial protein C receptor with phospholipid in the groove in complex with Gla domain of protein C. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Endothelial protein C receptor, ... | 著者 | Oganesyan, V, Oganesyan, N, Terzyan, S, Dongfeng, Q, Dauter, Z, Esmon, N.L, Esmon, C.T. | 登録日 | 2002-05-13 | 公開日 | 2002-06-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of the endothelial protein C receptor and a bound phospholipid. J.Biol.Chem., 277, 2002
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1L8J
| Crystal Structure of the Endothelial Protein C Receptor and Bound Phospholipid Molecule | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, ... | 著者 | Oganesyan, V, Oganesyan, N, Terzyan, S, Dongfeng, Q, Dauter, Z, Esmon, N.L, Esmon, C.T. | 登録日 | 2002-03-20 | 公開日 | 2002-06-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of the endothelial protein C receptor and a bound phospholipid. J.Biol.Chem., 277, 2002
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1T8B
| Crystal structure of refolded PHOU-like protein (gi 2983430) from Aquifex aeolicus | 分子名称: | Phosphate transport system protein phoU homolog | 著者 | Oganesyan, V, Kim, S.-H, Oganesyan, N, Jancarik, J, Adams, P.D, Kim, R, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2004-05-11 | 公開日 | 2004-12-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | 主引用文献 | Crystal structure of the "PhoU-like" phosphate uptake regulator from Aquifex aeolicus. J.Bacteriol., 187, 2005
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1T72
| Crystal structure of phosphate transport system protein phoU from Aquifex aeolicus | 分子名称: | Phosphate transport system protein phoU homolog | 著者 | Oganesyan, V, Kim, S.-H, Oganesyan, N, Jancarik, J, Adams, P.D, Kim, R, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2004-05-07 | 公開日 | 2004-12-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the "PhoU-like" phosphate uptake regulator from Aquifex aeolicus. J.Bacteriol., 187, 2005
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1EUE
| RAT OUTER MITOCHONDRIAL MEMBRANE CYTOCHROME B5 | 分子名称: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Oganesyan, V, Zhang, X. | 登録日 | 2000-04-19 | 公開日 | 2001-04-04 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Modulation of redox potential in electron transfer proteins: effects of complex formation on the active site microenvironment of cytochrome b5. FARADAY DISC.CHEM.SOC, 116, 2001
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8SUO
| BA.2/AZD1061/AZD3152 structure analysis | 分子名称: | AZD1061 heavy chain, AZD1061 light chain, AZD3152 heavy chain, ... | 著者 | Oganesyan, V, van Dyk, N, Dippel, A, Barnes, A, O'Connor, E. | 登録日 | 2023-05-12 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | X-ray crystal structure of BA.2 RBD bound by two neutralizing antibodies To Be Published
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2QL1
| Structural Characterization of a Mutated, ADCC-Enhanced Human Fc Fragment | 分子名称: | IGHM protein, ZINC ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Oganesyan, V, Wu, H, Dall'Acqua, W.F. | 登録日 | 2007-07-12 | 公開日 | 2008-04-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.534 Å) | 主引用文献 | Structural characterization of a mutated, ADCC-enhanced human Fc fragment Mol.Immunol., 45, 2008
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4YPG
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7R8U
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4N0F
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4N0U
| Ternary complex between Neonatal Fc receptor, serum albumin and Fc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Ig gamma-1 chain C region, ... | 著者 | Oganesyan, V, Wu, H, Dall'Acqua, W.F. | 登録日 | 2013-10-02 | 公開日 | 2014-02-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms. J.Biol.Chem., 289, 2014
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8TBB
| F9S, novel TIM-3 targeting antibody, bound to IgV domain of TIM-3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F9S Fab heavy chain, F9S Fab light chain, ... | 著者 | Oganesyan, V, van Dyk, N, Mazor, Y, Yang, C. | 登録日 | 2023-06-28 | 公開日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Generation of AZD7789, a novel PD-1 and TIM-3 targeting bispecific antibody, which binds to a differentiated epitope of TIM-3 To be published
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2HEK
| Crystal structure of O67745, a hypothetical protein from Aquifex aeolicus at 2.0 A resolution. | 分子名称: | BROMIDE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Oganesyan, V, Jancarik, J, Adams, P.D, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2006-06-21 | 公開日 | 2006-07-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structure of O67745_AQUAE, a hypothetical protein from Aquifex aeolicus. Acta Crystallogr.,Sect.F, 63, 2007
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6CYF
| PcrV fragment with bound Fab | 分子名称: | IgG1 antibody, heavy chain fragment, kappa light chain, ... | 著者 | Oganesyan, V. | 登録日 | 2018-04-05 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates. J. Infect. Dis., 218, 2018
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6BRB
| Novel non-antibody protein scaffold targeting CD40L | 分子名称: | CD40 ligand, Tn3-like, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Oganesyan, V, Baca, M, Thisted, T, Grinberg, L, Wu, H, Dall'Acqua, W.F. | 登録日 | 2017-11-30 | 公開日 | 2018-12-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity. Sci Transl Med, 11, 2019
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3C2S
| Structural Characterization of a Human Fc Fragment Engineered for Lack of Effector Functions | 分子名称: | IGHM protein, ZINC ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Oganesyan, V, Wu, H, Dall'Acqua, W.F. | 登録日 | 2008-01-25 | 公開日 | 2008-08-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural characterization of a human Fc fragment engineered for lack of effector functions. Acta Crystallogr.,Sect.D, 64, 2008
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3FJT
| Crystal structure of a human Fc fragment engineered for extended serum half-life | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | 著者 | Oganesyan, V, Wu, H, Dall'Acqua, W.F. | 登録日 | 2008-12-15 | 公開日 | 2009-03-24 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural characterization of a human Fc fragment engineered for extended serum half-life. Mol.Immunol., 46, 2009
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6BWV
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1S7O
| Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes | 分子名称: | Hypothetical UPF0122 protein SPy1201/SpyM3_0842/SPs1042/spyM18_1152 | 著者 | Oganesyan, V, Pufan, R, DeGiovanni, A, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2004-01-29 | 公開日 | 2004-06-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structure of the putative DNA-binding protein SP_1288 from Streptococcus pyogenes. Acta Crystallogr.,Sect.D, 60, 2004
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1OZ9
| Crystal structure of AQ_1354, a hypothetical protein from Aquifex aeolicus | 分子名称: | Hypothetical protein AQ_1354 | 著者 | Oganesyan, V, Busso, D, Brandsen, J, Chen, S, Jancarik, J, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2003-04-08 | 公開日 | 2003-09-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.894 Å) | 主引用文献 | Structure of the hypothetical protein AQ_1354 from Aquifex aeolicus. Acta Crystallogr.,Sect.D, 59, 2003
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1T75
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1JFD
| STRUCTURE OF INORGANIC PYROPHOSPHATASE | 分子名称: | INORGANIC PYROPHOSPHATASE, SULFATE ION | 著者 | Oganesyan, V, Avaeva, S.M, Huber, R, Harutyunyan, E.H. | 登録日 | 1997-05-31 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of Escherichia coli inorganic pyrophosphatase complexed with SO4(2-). Ligand-induced molecular asymmetry. FEBS Lett., 410, 1997
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1MJZ
| STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D97N | 分子名称: | INORGANIC PYROPHOSPHATASE | 著者 | Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R. | 登録日 | 1997-02-08 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97. Biochemistry Mosc., 63, 1998
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1MJW
| STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D42N | 分子名称: | INORGANIC PYROPHOSPHATASE, SULFATE ION | 著者 | Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Samygina, V.R, Huber, R. | 登録日 | 1997-02-08 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97. Biochemistry Mosc., 63, 1998
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1MJX
| STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D65N | 分子名称: | INORGANIC PYROPHOSPHATASE, SULFATE ION | 著者 | Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R. | 登録日 | 1997-02-08 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97. Biochemistry Mosc., 63, 1998
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